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광열치료의 열 투여량에 따른 세포 자멸사에 대한 수치적 연구
김무중(Moojoong Kim),김관택(Gwantaek Kim),김동혁(Donghyuk Kim),이희진(Heejin Kim),유재석(Jaisuk Yoo),김동권(Dong-Kwon Kim),김현정(Hyun Jung Kim) 대한기계학회 2018 대한기계학회 춘추학술대회 Vol.2018 No.12
Photothermal therapy(PTT) is a therapy for selective ablation of the tumor by using a photothermal effect. However, in spite of using the photothermal effect, which is one of the fields of heat transfer, the research on heat transfer for photothermal therapy is insufficient. In photothermal therapy, GNPs (gold nanoparticles) are used as a photothermal enhancer to selective ablation of tumor. At this time, since the photothermal effect are different depending on the characteristics of the GNPs, and thermal and optical conditions of NIR laser, it is important to find an optimal condition suitable for selective ablation for effective photothermal therapy. In previous photothermal therapy studies, the temperature distribution in tumor tissues has been studied qualitatively. However, the correlation between the death of tumor tissue and thermal and optical conditions of NIR laser has not been quantitatively studied in terms of heat transfer. Therefore, in this study, the conditions (e.g. intensity, beam radius) of the lasers satisfying the apoptosis temperature (43℃ ~ 50℃ , which can effectively ablate tumors) were obtained for various sizes of tumor (width: 2mm ~ 10mm, depth: 0.5mm ~ 4.5mm) using numerical analysis. And quantitative analysis of the apoptosis rate of tumor tissue according to the thermal and optical conditions of photothermal therapy was performed.
탈취필터 내 첨착활성탄의 쏠림 형태와 충전율에 따른 탈취성능에 대한 실험
도수윤(Soo Yun Doh),김관택(Gwantaek Kim),윤백(Baek Youn),김현정(Hyunjung Kim),진유성(Yu-Sung Jin),문연진(Yeon-Jin Moon),김중호(Jung-ho Kim) 대한설비공학회 2021 대한설비공학회 학술발표대회논문집 Vol.2021 No.6
Recently, interest in indoor air quality has been increasing, and purification of various harmful gases generated indoors, along with fine dust, is drawing attention as an important factor. Deodorization filters, which typically use impregnated activated carbon, are used with dust collection filters to remove these harmful gases. Plate deodorization filters using impregnated activated carbon generally consist of small cells of a certain shape, and are made by filling impregnated activated carbon in the form of small grains formed by mixing impregnated activated carbon powder and adhesive, and attaching nets on both sides. This process of charging impregnated activated carbon is usually carried out manually, and therefore, uniform charging is not achieved, which can lead to the concentration of impregnated activated carbon. In this study, the deodorization performance was evaluated by measuring the purification rate of the five major harmful gases (formaldehyde, acetaldehyde, acetic acid, ammonia, and toluene) through experiments on various forms of impregnated activated carbon non-uniform charging forms. We also measure the change in deodorization performance with changes in various charge based on the charge of 220g (100% charge rate). Therefore, the results of this study are considered to be an important reference for establishing criteria for managing processes and quality in the manufacture of deodorized filters in the future by considering the phenomenon of non-uniform charging and the impact of charging rates on performance.