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두피에 단일 윤상 판으로 나타난 것으로 사료되는 2기 매독
구상현 ( Sang Hyeon Ku ),윤종현 ( Jong Hyun Yoon ),조은별 ( Eun Byul Cho ),박경훈 ( Gyeong Hun Park ),박은주 ( Eun Joo Park ),권인호 ( In Ho Kwon ),김광호 ( Kwang Ho Kim ),김광중 ( Kwang Joong Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.12
A 32-year-old man is being presented with a 1-week history of erythematous annular flat plaque with scales on his scalp. He displays only a solitary skin lesion on his scalp without any presence or other histories for other skin lesions or constitutional symptoms. It is difficult to consider the possibilities of syphilis based on such clinical findings. A diagnosis of syphilid is being made on the basis of clinical, serological and histological findings. Herein, we report an interesting case of secondary syphilis which is presented as a solitary annular plaque on the scalp. (Korean J Dermatol 2013;51(12):987∼989)
건강검진자를 대상으로 한 자외선 노출, 체내 지방 분포, 대사 변화와의 관련성에 대한 단면적 관찰 연구
백유진 ( Yu Jin Paek ),구상현 ( Sang Hyeon Ku ),권인호 ( In Ho Kwon ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.12
Background: The age-associated loss of subcutaneous fat with the accumulation of visceral fat consequently leads to several deleterious health outcomes such as dyslipidemia, insulin resistance, and metabolic syndrome. A recent research has shown that acute ultraviolet (UV) irradiation can reduce subcutaneous fat. Objective: The purpose of our study is to investigate whether chronic UV radiation can reduce subcutaneous fat, increase visceral fat, and lead to additional metabolic changes. Methods: We analyzed the abdominal computed tomography images of the 98 subjects attending our health examination center to calculate the amount of subcutaneous fat and visceral fat. Questionnaire surveys were conducted to analyze the degree of daily UV exposure, sunscreen use, and physical activity. Weight, height, blood pressure (BP), liver function test, lipid profiles, and glucose metabolism were also assessed. Results: In the analysis of covariance adjusted for age, sex, and physical activity, the visceral fat amount in the high UV exposure group was significantly higher than that in the low UV exposure group (p=0.043), and the subcutaneous/total fat ratio in the high UV group was significantly lower than that in the low UV group (p=0.048). The high UV group had higher levels of fasting insulin, homeostasis model assessment of insulin resistance, systolic BP, and diastolic BP than the low UV exposure group (p=0.039, 0.012, 0.004, and 0.002, respectively). Conclusion: Our results suggest that chronic UV radiation could change body fat distribution and lead to additional changes, including changes in glucose metabolism and BP. (Korean J Dermatol 2014;52(12):873∼879)