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원저(原著) : 혈소판 농축액 교차시험에서 발견된 항-E+c+Dia의 multiple antibody 검출 1예
이종숙 ( J. S. Lee ),구미숙 ( M. S. Ku ),임연희 ( Y. H. Lim ),박주희 ( J. H. Park ),홍인표 ( I. P. Hong ) 대한임상병리사협회 1997 임상수혈검사학회 발표자료집 Vol.4 No.1
The Diego blood group system is controlled by two allelic genes, Di(a) and Di(b). Di(a) is known to be absent in pure Caucasians but present exclusively among Amerio-can Indians and Mongolians. The incidences of Di(a) antigen among Koreans are reported to be 6.14 to 14.5%. Recently the authors experienced a case with anti-Di(a) in a patient serum, which detected by routine bromelin cross-matching test selected with R1R1 blood for platelet concentrates. The case detected by irregular antibody identification test at an antiglobulin phase. Previously the patient was been detected anti-E and anti-c, had been transfused with R1R1 cells during the treatment for Aplastic Anemia, probably contributing to the presence of irregular antibody "anti ? Di(a)". After the identification of anti-E+c+Di(a) antibody the patient has been transfused with the selected compatible R1R1 Di(a-b+) blood, which could prevent the possible delayed hemolytic transfuion reaction.
이종숙 ( J S Lee ),박희정 ( H J Park ),구미숙 ( M S Ku ),홍인표 ( I P Hong ) 대한임상검사과학회 1991 대한임상검사과학회지(KJCLS) Vol.23 No.1
Autoantibody react on antigen existing on the surface of RBC, itself. Particularly, we considered warm autoantibody. The specificity of autoantibodies associated with warm autoimmune homolytic anemia is compl,~ x. so blood transfusion is very difficult. The authors experienced a case of autoimmune hemolytic anemia that caused by Rh-related antibody. No autoantibody specificity was clear out. But we could prove that the patient``s serum have Rh -related specificity with a difference of intencity of serum reaction. Special test proved major antibody are an ti-E & c. Blood transfusion was unavailable. We were . helped that selected compatible blood with crossmatching of R1 Rt cell in stead of many crossmatching. So we have reported warm autoantibody identification methods and signifirance of transfusion with brief review of literatures.