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RISS 인기검색어
- 검색키워드
- 저자 : 玄武燮 (검색결과 3 건)
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玄武燮,崔日薰,徐舜圭 우석대학교 의과대학 1969 우석의대잡지 Vol.6 No.2
The etiology and pathogenesis of essential hypertension are controversial. Most authorities agree with the hereditary factor and environmental factors in essential hypertension. Mental stress and excessive salt intake have been claimed to be major environmental factors. However, the abnormality of sodium metabolism in essential hypertension is not yet clarified. Since Korean prisoners have been exposed to excessive salt intake and to mental stress, the author studied 506 sentenced prisoners regarding their blood pressure, incidence of hypertension, related family history, physical findings and laboratory examinations. The 24 hour urinary sodium, chloride and potassium Were measured for 3 consecutive days in 30 normotensive and 45 hypertensive prisoners with a regular diet (high salt diet) and with a partial intake of high salt diet (relative high salt diet). The osmotic pressure of plasma and 24 hour urine, osmolal clearance and free water clearance were measured by Fiske's osmometer in 30 normotensive and 45 hypertensive prisoners respectively. For the purpose of studying sodium metabolism, basal sodium excretion test, oral and intravenous salt loading test, and salt deprivation test were carried out in 15 normotensive and 45 hypertensive prisoners. Basal sodium excretion test and oral salt loading test: After supper, no food and drink was allowed for 12 hours. The next morning, the urine was collected (except the first one) followed by the intake of 100 ml of water and 0.15 gm of salt every hour for seven times. Three gm of salt was added to the fourth intake of salt and water, and then Na, Cl and K was measured in the collected urine every hour for seven times. Salt deprivation test: As in the above mentioned basal sodium excretion test, the next morning Na, Cl and K are measured in the collected urine every hour for seven times with the intake of only 100 ml. of water (without salt). The results of studies were as follows: 1. In the total prisoners, the incidence of systolic hypertension was 58.3%, while that of diastolic hypertension was 51.6%; and the former gradually increased with age showing high rate of 81.7% in the age group of 55-59 years, while the latter showed a rate of 74.9% in the age group over 60 years. 2. The family history of hypertension and cerebral hemorrhage was 27.2%, proteinuria 5.6%, abnormal Fishberg's concentration test 35%, abnormal ECG 35% and the eyeground change above Keith-Wagener grade 1 was 47% in the hypertensive prisoners. 3. In the prisoner's daily diet the average content of salt (NaCl) was 46.8 gm, 26.4 gm of which was excreted in the 24 hour urine of normotensive prisoners. In the hypertensive prisoners, the average amount of 24 hour urinary salt excretion was 22.0 gm in the mild cases, 21.9 gm in the moderate cases and 19.4 gm in the severe cases. This was slightly less than in the normotensive prisoners. 4. The plasma osmotic pressure, the daily urinary osmotic pressure, the osmolal clearance and the free water clearance were measured and there was no significant difference between the normotonsive and hypertensive prisoners. 5. a) In the renal excretory function of sodium, there was little difference between the normotensive and hypertensive prisoners in the basal sodium excretion test. b) In the oral salt loading test, the greatest value of urinary sodium excretion was obtained in one hour in the normotensive prisoners and two hours in the hypertensive prisoners. c) The salt deprivation test showed gradual decrease in the excretion of the urinary sodium after 17 hour-fasting in the normotensive prisoners, while the results in the hypertensive cases was indistinct. 6. These data suggested that there was some kind of abnormal sodium metabolism in hypertension.
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崔鎭,金昌烈,玄武燮 中央醫學社 1968 中央醫學 Vol.14 No.3
A case of the granulose cell, tumor in the left side ovary and the papillary serous cyst- adenocarcinoma in the opposite side ovary is reported as follows: After total oophorectomy of the granulosa cell tumor in the left side ovary was performed, the papillary serous cystadenocarcinoma was developed in the opposite side ovary. The carcinoma was extended and implanted to the fallopian tub, omentum, abdominal wall and cul de sac. The literatures on the granulosa cell tumor and serous cystadenocarcinoma of ovary were briefly reviewed.
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