2010 Asian WTO Research Network (AWRN) Seoul Meeting : China`s Strategy and Practice with Free Trade Area

( Wei Qun Yao ),( Bo Chen ) 고려대학교 법학연구원 2010 Korea University Law Review Vol.8 No.-

A Compact Top-View Conformal Optical System Based on a Single Rotating Cylindrical Lens with Wide Field of Regard

Lin yao Yu,Qun Wei,Jinggao Zheng,Mingda Ge,Tian yi Zhang 한국광학회 2016 Current Optics and Photonics Vol.20 No.1

A new compact conformal dome optical system was established, and the aberration characteristics ofthe dome were investigated using Zernike aberration theory. The aberrations induced by the dome atdifferent fields of regard (FORs) from 30° to 100° were effectively balanced by a rotating cylindrical lens. This kind of optical system can be widely used in top-view optical searching devices. A design methodwas introduced and the optimization results analyzed in detail. The results showed that the Zernikeaberrations produced by the conformal dome were decreased dramatically. Also, a complete conformaloptical system was designed, to further illustrate the aberration correction effect of the rotating cylindricallens. Using a cylindrical lens not only provided a large FOR, but also simplified enormously the structureof the conformal optical system.

A Design of Mid-wave Infrared Integral Catadioptric Optical System with Wide FOV

Lin yao Yu,Hong guang Jia,Qun Wei,Hu hai Jiang,Tian yi Zhang,Chao Wang 한국광학회 2013 Current Optics and Photonics Vol.17 No.2

In order to deduce the difficulty of fixing the Ritchey-Chretien (R-C) dual reflective optical system and enhance the stability of the secondary mirror, a compact integral structure is presented here composed of two transmitting and two reflective aspheric surfaces. The four surfaces were manufactured from a single germanium lens and integrated together. The two reflective surfaces formed by coating the inner reflecting films were assembled in one lens. It makes the installation of the two mirrors easier and the structure of the secondary mirror more stable. A design of mid-wave infrared (MWIR) compact imaging system is presented with a spectral range chosen as 3.7-4.8 μm. The effective focal length is f=90 mm. The field of view (FOV) for the lens is 4.88°. It has good imaging capability with Modulation Transfer Function (MTF) of all field of view more than 0.55 close to the diffraction limitation. Outdoor experiments were carried out and it is shown that the integral catadioptric optical system performs well on imaging.

Development and Evaluation of a Patient-Reported Outcome (PRO) Scale for Breast Cancer

Zhang, Jun,Yao, Yu-Feng,Zha, Xiao-Ming,Pan, Li-Qun,Bian, Wei-He,Tang, Jin Hai Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

Background: This study was guided by principles of the theoretical system of evidence-based medicine. In particular, when searching for evidence of breast cancer, a measuring scale is an instrument for evaluating curative effects in accordance with the laws and characteristics of medicine and exploring the establishment of a system for medically assessing curative effects. At present, there exist few tools for evaluating curative effects. Patient-reported outcomes (PROs) refer to outcomes directly reported by patients (without input or explanations from doctors or other intermediaries) with respect to all aspects of their health. Data obtained from PROs provide evidence of treatment effects. Materials and Methods: In accordance with the tenets of theoretical medicine and ancient medical theory regarding breast cancer, principles for developing a PRO scale were established, and a theoretical model was developed and a literature review was performed, items from this pool were combined and split, and an initial scale was constructed. After a pilot survey and additional modifications, a pre-questionnaire scale was formed and used in a field investigation. After the application of statistical methods, the item pool was used to create a formal scale. The reliability, validity and feasibility of this formal scale were then assessed. Results: In a clinical investigation, 479 responses were recovered, with an acceptance rate of 95%. a combination of various methods was employed, and the items that were selected by all methods or more than half of the methods were employed in the questionnaire. In these cases, the screening methods were combined with certain features of the item, A total of four domains and 38 items were reserved. The reliability analysis indicated that the PRO scale was relatively reliable. Conclusions: Scientific assessment proved that the proposed scale exhibited good reliability and validity. This scale was readily accepted and could be used to assess the curative effects of medical therapy. However, given the limited scope of this investigation, the capacity for adapting this scale to incorporate other theories could not be determined.

Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout

Geng Ya-Wei,Zhang Zhen,Jin Han,Da Jun-Long,Zhang Kai,Wang Jian-Qun,Guo Yu-Yao,Zhang Bin,Li Ying 한국유전학회 2022 Genes & Genomics Vol.44 No.2

Background: Fam20c is intimately related to tissue development and diseases. At present, it has been reported that Fam20c regulates the mineralization of osteoblasts, but there are few reports on other effects. Objective: To study the effect of Fam20c on osteoblasts by knocking out the Fam20c gene. Methods: Fam20c knockout osteoblasts were constructed by transfecting mouse osteoblasts with lentivirus. The proliferation, migration and mineralization of Fam20c knockout cells were detected by CCK-8, scratch test and alizarin red staining assays. The subcellular structure was observed by transmission electron microscopy. RT-PCR was used to detect the differential expression of mesenchymal-to-epithelial transition (MET)-related marker genes and core transcription factors. The differential expression of MET-related proteins was detected by immunofluorescence or Western blot. Transcriptome analysis of Fam20c knockout osteoblasts was performed, and real-time PCR was used to verify transcriptome analysis related to MET. Results: The proliferation ability of osteoblasts was not significantly changed after Fam20c deletion, but the migration ability and mineralization ability were significantly weakened. There were tight junctions between Fam20c knockout cells. The expression of mesenchymal cell marker genes and core transcription factors was significantly decreased, and the expression of epithelial cell marker genes was significantly increased. The expression of mesenchymal cell marker proteins was significantly decreased, and the expression of epithelial cell marker proteins was significantly increased. Multiple signalling molecules and pathways involved in MET have changed. Conclusions: Knockdown of Fam20c resulted in MET. Fam20c affects the transcription of key factors in osteoblast MET.

Analysis on Postoperative Efficacy of Radical Hepatectomy for Patients with Non-HBV/HCV Hepatocellular Carcinoma

Zhang, Zhi-Ming,Zhang, Yu-Mei,Yao, Feng,Yi, Ping,Huang, Shang,Liu, Jian-Yong,Xiang, Bang-De,Yuan, Wei-Ping,Li, Le-Qun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

Objective: Patients with hepatocellular carcinoma (HCC) in stage Barcelona Clinic Liver Cancer (BCLC)-A were grouped based on whether they were accompanied with hepatitis B virus (HBV) infection or not so as to explore the clinical characteristics and prognostic conditions of HCC patients with non-HBV/hepatitis C virus (HCV). Materials and Methods: Clinical data of 64 stage BCLC-A HCC patients with non-HBV/HCV infection (observation group) who received radical hepatectomy in the Affiliated Cancer Hospital of Guangxi Medical University from January, 2006 to November, 2014 were retrospectively analyzed and compared with those of 409 stage BCLC-A HCC patients with HBV infection (control group) in corresponding period. Results: The postoperative 1-, 3- and 5-year recurrent rates of the observation group were 25%, 38.6% and 48.8%, with postoperative mean and median disease-free survival time being 49.1 months and 62.0 months, respectively. Additionally, the postoperative 1-, 3- and 5-year survival rates of observation group were 90.1%, 72.7% and 62.0%, with the mean and median survival times being 54.4 months and 70.0 months, respectively. Conclusions: The 1-year recurrent rate is the highest in HCC patients with non-HBV/HCV, and almost half of the patients have recurrence within 1 year, after which the recurrent rate decreases along with the time.