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      • Endoscopy and Imaging Modalities/Basic Science of Gastrointestinal Disorders/Miscellaneous : Hemodynamic Evaluation Of Esophageal Varices Resistant To Injection Sclerotherapy By Endoscopic Ultrasonography

        ( Talcahiro Sato ),( Katsu Yamazaki ),( Jouji Toyota ),( Yoshiyasu Karino ),( Takumi Ohmura ),( Toshihim Suga ) 대한소화기학회 2007 SIDDS Vol.9 No.-

        Background/Aims: We evaluated hemodynamics of esophageal varices that were resistant to endoscopic injection sclerotherapy (EIS) Using 5% ethanolamine oleate with iopamidol (5% EOI) and in need of EIS using absolute alcohol (AA). Methods: Consecutive 490 patients who underwent hemodynamic evaluation using endoseopic color Doppler ultrasonography (ECDUS) and ultrasonic microprobe (UMP) were studied. Results: Nine patients were resistant to EIS using 5% EOI and the additional use of AA in this group was performed (AA group). Various parameters were compared between the 481 patients who had been administered EIS using 5% EOI (EO group) and the 9 patients in AA group. The mean number of EIS treatments in the AA group (6.8±3.4) was significantly greater than in the EO group (4.4±2.1 times) (p<0.01). The mean amount of 5% EOI provided in the AA group (31.1±17.4 mL) was significantly larger than in the EO group (14.9±8.8 mL) (P<0.001). The mean velocity of esophageal varices in the AA group (13.6±3.2 cm/s) was significantly higher than in the EO group (9.4±3.1 cm/s) (P<0.001) determined by ECDUS. The mean diameter of esophageal varices as found by UMP was 8.0±3.5 mm in the AA group and 4.6±2.4 mm in the EO group, with the difference being significant (p<0.01). The mean diameter of the perforating vein was 3.8±1.9 mm in the AA group and 2.1±0.5 mm in the EO group as shown by UMP, a difference that was statistically significant (p<0.01). Conclusions: Hemodynamic evaluation revealed that the esophageal varices were more severe in the AA group than in the EO group.

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