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        Graphene derivatives: Properties and potential food applications

        Swati Joshi,Hanuman Bobade,Rajan Sharma,Savita Sharma 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.123 No.-

        Graphene and its derivatives have been recently investigated for their potential applications in food processingindustry. Graphene derivatives have successfully plunged into packaging and electrochemicalsensing trades of the food industry. However, their multitudinous applications in the field of analytics,milk and beverage technology are still unexplored. This bibliographic review aims to enlighten the potentialapplications of graphene derivatives for the food industry. It summarizes derivatives of graphene,their distinctive properties and specific applications in food. A detailed overview of utilization of graphenederivatives as bio-composites; intelligent and active packaging; detection of pesticides, antinutrients;desalination and water treatment; extraction; production of tailored milk is provided. The graphenederivatives possessed several suitable and versatile properties for its potential applications in food processing. Graphene could be used as potent packaging and sensing materials. Also, graphene possessedantifouling properties and are excellent membrane for lactose removal from milk and water desalination. Toxicity studies refuted any major cytotoxicity, thereby escalating their scope in several aspects of foodtechnology. Further detailed research is required to study their migration behavior and design simplifiedmethods for its prevention. Ample scope of research is available for utilizing graphene in various segmentsof food production.

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        Simultaneous Determination of Anthraquinone, Flavonoids, and Phenolic Antidiabetic Compounds from Cassia auriculata Seeds by Validated UHPLC Based MS/MS Method

        ( Aboli Girme ),( Ganesh Saste ),( Ashish Chinchansure ),( Swati Joshi ),( Rahul Kunkulol ),( Lal Hingorani ),( Bhushan Patwardhan ) 한국질량분석학회 2020 Mass spectrometry letters Vol.11 No.4

        A systematic isolation and characterization study for Cassia auriculata (CA) seeds resulted in identifying antidiabetic compounds 1,3,8-trihydroxyanthraquinone and quercetin, quercetin-3-O-rutinoside, gallic acid, caffeic acid, ferulic acid, and ellagic acid. The ultra-high-performance liquid chromatography based triple quadrupole mass spectrometry methodology was developed and validated for simultaneous identification and confirmation of these compounds from CA seeds. Multiple reaction monitoring (MRM) based quantification method was developed with MRM optimizer software for MS<sub>1</sub> and MS<sub>2</sub> mass analysis. The method was optimized on precursor ions and product ions with the ion ratio of each compound. The calibration curves of seven bioactive analytes showed excellent linearity (r<sup>2</sup> ≥ 0.99). The quantitation results found precise (RSD, < 10 %) with good recoveries (84.58 to 101.42%). The matrix effect and extraction recoveries were found within the range (91.66 to 102.11%) for the CA seeds. This is the first MS/MS-based methodology applied to quantifying seven antidiabetic compounds in CA seeds and its extract for quality control purposes.

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