http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Role of Curcuma longa, a traditional ayurvedic medicinal plant, in diabetes
Ameeta RaviKumar,Sudha Ponnusamy,Smita Zinjarde,Shobha Bhargava 셀메드 세포교정의약학회 2012 TANG Vol.2 No.4
Curcuma longa belongs to the family Zingiberaceae and can be found in the tropical and subtropical regions of the world. It is widely used in Asiatic countries, especially India and South East Asia where it is cultivated commercially as a condiment. Its rhizomes exhibit anti-inflammatory, anti-human immunodeficiency virus, anti-bacterial, antioxidant effects, nematocidal activities, antiproliferative and antiangiogenic activities and are of pharmaceutical importance. Another relevant medicinal property exhibited by it is antidiabetic property which is reviewed here. Studies on the efficacy of crude C.longa extracts against type 2 diabetes in murine models reveal that it demonstrates a hypoglycemic effect by lowering the blood glucose levels under in vivo conditions. Clinical studies have revealed the safety of curucmin (major principle component exhibiting pharmaceutical properties from C.longa) on humans but with very low bioavailability. In view of its effective hypoglycemic effect and its low bioavailability, further studies are needed for the characterization of the bioactive principles and formulating the development of C.longa extracts as a novel anti-diabetic therapeutic agent.
Aakanksha Vatsal,Chirag Potdar,Smita S. Zinjarde,V. Ravi Kumar,Bhasker D. Kulkarni,Ameeta RaviKumar 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.41 No.-
Use of persistent organobromines for industrial applications has led to their accumulation inenvironment. Yarrowia lipolytica NCIM 3589, a tropical marine yeast, degrades and detoxifiesbromocompounds by an initial hydrolytic step. By optimizing culture conditions with 1-bromodecaneas reference compound, the dehalogenase involved was remarkably enhanced 13-fold (384.13 U/ml) by ahybrid statistical Plackett–Burman and Box–Behnken design of experiments. Studies bring out in a novelway the role of aliasing and other masked interactions in growth media factors. Importantly, the enzymeacted on C3–C16 bromoalkanes and bromoaromatics, thereby generalizing the ‘green chemistry’applicability of optimized media formulation for biotechnological applications.
( Mahesh Khot ),( Rohini Gupta ),( Kadambari Barve ),( Smita Zinjarde ),( Sanjay Govindwar ),( Ameeta Ravikumar ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.4
This study evaluated the microbial conversion of coconut oil waste, a major agro-residue in tropical countries, into single cell oil (SCO) feedstock for biodiesel production. Copra cake was used as a low-cost renewable substrate without any prior chemical or enzymatic pretreatment for submerged growth of an oleaginous tropical mangrove fungus, Aspergillus terreus IBB M1. The SCO extracted from fermented biomass was converted into fatty acid methyl esters (FAMEs) by transesterification and evaluated on the basis of fatty acid profiles and key fuel properties for biodiesel. The fungus produced a biomass (8.2 g/l) yielding 257 mg/g copra cake SCO with ~98% FAMEs. The FAMEs were mainly composed of saturated methyl esters (61.2%) of medium-chain fatty acids (C12-C18) with methyl oleate (C18:1; 16.57%) and methyl linoleate (C18:2; 19.97%) making up the unsaturated content. A higher content of both saturated FAMEs and methyl oleate along with the absence of polyunsaturated FAMEs with ≥4 double bonds is expected to impart good fuel quality. This was evident from the predicted and experimentally determined key fuel properties of FAMEs (density, kinematic viscosity, iodine value, acid number, cetane number), which were in accordance with the international (ASTM D6751, EN 14214) and national (IS 15607) biodiesel standards, suggesting their suitability as a biodiesel fuel. The low cost, renewable nature, and easy availability of copra cake, its conversion into SCO without any thermochemical pretreatment, and pelleted fungal growth facilitating easier downstream processing by simple filtration make this process cost effective and environmentally favorable.
( Rokhbakhsh Zamin Farokh ),( Dhara Sachdev ),( Nadia Kazemi Pour ),( Anupama Engineer ),( Karishma R. Pardesi ),( Smita Zinjarde ),( Prashant K. Dhakephalkar ),( Balu A. Chopade ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.6
A total of 31 Acinetobacter isolates were obtained from the rhizosphere of Pennisetum glaucum and evaluated for their plant-growth-promoting traits. Two isolates, namely Acinetobacter sp. PUCM1007 and A. baumannii PUCM1029, produced indole acetic acid (10-13 μg/ml). A total of 26 and 27 isolates solubilized phosphates and zinc oxide, respectively. Among the mineral-solubilizing strains, A. calcoaceticus PUCM1006 solubilized phosphate most efficiently (84 mg/ml), whereas zinc oxide was solubilized by A. calcoaceticus PUCM1025 at the highest solubilization efficiency of 918%. All the Acinetobacter isolates, except PUCM1010, produced siderophores. The highest siderophore production (85.0 siderophore units) was exhibited by A. calcoaceticus PUCM1016. Strains PUCM1001 and PUCM1019 (both A. calcoaceticus) and PUCM1022 (Acinetobacter sp.) produced both hydroxamate- and catechol-type siderophores, whereas all the other strains only produced catechol-type siderophores. In vitro inhibition of Fusarium oxysporum under iron-limited conditions was demonstrated by the siderophore-producing Acinetobacter strains, where PUCM1018 was the most potent inhibitor of the fungal phytopathogen. Acinetobacter sp. PUCM1022 significantly enhanced the shoot height, root length, and root dry weights of pearl millet seedlings in pot experiments when compared with controls, underscoring the plant-growth-promoting potential of these isolates.