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        On Efficient Processing of Continuous Reverse Skyline Queries in Wireless Sensor Networks

        ( Bo Yin ),( Siwang Zhou ),( Shiwen Zhang ),( Ke Gu ),( Fei Yu ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.4

        The reverse skyline query plays an important role in information searching applications. This paper deals with continuous reverse skyline queries in sensor networks, which retrieves reverse skylines as well as the set of nodes that reported them for continuous sampling epochs. Designing an energy-efficient approach to answer continuous reverse skyline queries is non-trivial because the reverse skyline query is not decomposable and a huge number of unqualified nodes need to report their sensor readings. In this paper, we develop a new algorithm that avoids transmission of updates from nodes that cannot influence the reverse skyline. We propose a data mapping scheme to estimate sensor readings and determine their dominance relationships without having to know the true values. We also theoretically analyze the properties for reverse skyline computation, and propose efficient pruning techniques while guaranteeing the correctness of the answer. An extensive experimental evaluation demonstrates the efficiency of our approach.

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        Evaluating Pharmacological Effects of Two Major Components of Shuangdan Oral Liquid: Role of Danshensu and Paeonol in Diabetic Nephropathy Rat

        Chen, Ying,Liu, Zhuying,Zhou, Fuxing,Zhao, Hang,Yang, Qian,Li, Hua,Sun, Jiyuan,Wang, Siwang The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5

        Shuangdan oral liquid (SDO) containing radix Salviae miltiorrhizae (Chinese name Danshen) and cortex moutan (Chinese name Mudanpi) is a traditional Chinese medicine using for treating vascular diseases. Danshensu (DSS) is a main effective monomer composition derived from radix Salviae miltiorrhizae and paeonol (Pae) from cortex moutan. Although the two herbs are widely used in traditional Chinese medicine, the pharmacological functions of their active compositions were not reported. Therefore, the research of DSS and Pae in mechanisms and pharmacodynamics interaction can provide scientific evidence to support clinical application. The diabetic nephropathy (DN) rats which were induced by streptozotocin (STZ) were treated with SDO, DSS, Pae, and DSS+Pae for eight weeks. The positive effects on DN animal models were investigated by detection of physiological and biochemical indexes and oxidative stress markers, within five treatments: SDO, DSS, Pae, DSS+Pae and insulin group. Compared with the model group, the DSS+Pae group improved the renal function, blood lipid metabolism and blood viscosity, increased the vitality of T-SOD or T-AOC and decreased the level of MDA or NO after the treatment. The study was successfully showed that the DSS+Pae group could delay the process of DN, especially in the renal injury part of histopathology changes. Our results suggest that the co-administration of DSS and Pae significantly may play a protective role in DN rats through decreasing the oxidative stress and improving the blood lipid metabolism mechanisms.

      • KCI등재

        Evaluating Pharmacological Effects of Two Major Components of Shuangdan Oral Liquid: Role of Danshensu and Paeonol in Diabetic Nephropathy Rat

        ( Ying Chen ),( Zhuying Liu ),( Fuxing Zhou ),( Hang Zhao ),( Qian Yang ),( Hua Li ),( Jiyuan Sun ),( Siwang Wang ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5

        Shuangdan oral liquid (SDO) containing radix Salviae miltiorrhizae (Chinese name Danshen) and cortex moutan (Chinese name Mudanpi) is a traditional Chinese medicine using for treating vascular diseases. Danshensu (DSS) is a main effective monomer composition derived from radix Salviae miltiorrhizae and paeonol (Pae) from cortex moutan. Although the two herbs are widely used in traditional Chinese medicine, the pharmacological functions of their active compositions were not reported. Therefore, the research of DSS and Pae in mechanisms and pharmacodynamics interaction can provide scientific evidence to support clinical application. The diabetic nephropathy (DN) rats which were induced by streptozotocin (STZ) were treated with SDO, DSS, Pae, and DSS+Pae for eight weeks. The positive effects on DN animal models were investigated by detection of physiological and biochemical indexes and oxidative stress markers, within five treatments: SDO, DSS, Pae, DSS+Pae and insulin group. Compared with the model group, the DSS+Pae group improved the renal function, blood lipid metabolism and blood viscosity, increased the vitality of T-SOD or T-AOC and decreased the level of MDA or NO after the treatment. The study was successfully showed that the DSS+Pae group could delay the process of DN, especially in the renal injury part of histopathology changes. Our results suggest that the co-administration of DSS and Pae significantly may play a protective role in DN rats through decreasing the oxidative stress and improving the blood lipid metabolism mechanisms.

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