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RISS 인기검색어
- 검색키워드
- 저자 : ( Shahzad Amin Sheikh ) (검색결과 3 건)
- 무료
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An Adaptive Companding Scheme for Peak-to-average Power Ratio Reduction in OFDM Systems
( Sana Mazahir ),( Shahzad Amin Sheikh ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.12
Orthogonal frequency division multiplexing (OFDM) signals suffer from the problem of high peak-to-average power ratio (PAPR), which complicates the design of analog front-end of the system. Companding is a well-known PAPR reduction technique that involves transforming signal amplitudes using a deterministic function. OFDM signal amplitude, on average, is Rayleigh distributed but the distribution can vary significantly from symbol to symbol, especially when constellation size increases. In this paper, a new adaptive companding scheme is proposed along with its design methodology aiming at optimizing the compander performance by accommodating this variation in its design. This is achieved by designing compander parameters separately for statistically dissimilar symbols in OFDM waveform and making the compander select from these parameters, during run-time, according to the features of input symbols.
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Optimal Design of Piecewise Linear Companding Transforms for PAPR Reduction in OFDM Systems
( Sana Mazahir ),( Shahzad Amin Sheikh ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.1
Orthogonal frequency division multiplexing (OFDM) signals suffer from the problem of large peak-to-average power ratio (PAPR) which complicates the design of the analog front-end of the system. Companding is a well-known PAPR reduction technique that reduces the PAPR by transforming the signal amplitude using a deterministic function. In this paper, a novel piecewise linear companding transform is proposed. The design criteria for the proposed transform is developed by investigating the relationships between the compander and decompander`s profile and parameters with the system`s performance metrics. Using analysis and simulations, we relate the companding parameters with the bit error rate (BER), out-of-band interference (OBI), amount of companding noise, computational complexity and average power. Based on a set of criteria developed thereof, we formulate the design of the proposed transform. The main aim is to preserve the signal`s attributes as much as possible for a predetermined amount of PAPR reduction. Simulations are carried out to evaluate and compare the proposed scheme with the existing companding transforms to demonstrate the enhancement in PAPR, BER and OBI performances.
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Cassia Angustifolia Primed ASCs Accelerate Burn Wound Healing by Modulation of Inflammatory Response
Tasneem Saba,Ghufran Hafiz,Azam Maryam,Arif Amna,Bin Umair Musab,Yousaf Muhammad Amin,Shahzad Khurrum,Mehmood Azra,Malik Kausar,Riazuddin Sheikh 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.1
Background: Thermal traumas impose a huge burden on healthcare systems. This merits the need for advanced but cost-effective remedies with clinical prospects. In this context, we prepared a regenerative 3D-construct comprising of Cassia angustifolia extract (SM) primed adipose-derived stem cells (ASCs) laden amniotic membrane for faster burn wound repair. Methods: ASCs were preconditioned with SM (30 µg/ml for 24 h), and subsequently exposed to in-vitro thermal injury (51 °C,10 min). In-vivo thermal injury was induced by placing pre-heated copper-disc (2 cm diameter) on dorsum of the Wistar rats. ASCs (2.0 × 105) pre-treated with SM (SM-ASCs), cultured on stromal side of amniotic membrane (AM) were transplanted in rat heat-injury model. Non-transplanted heat-injured rats and non-heat-injured rats were kept as controls. Results: The significantly upregulated expression of IGF1, SDF1A, TGFβ1, VEGF, GSS, GSR, IL4, BCL2 genes and downregulation of BAX, IL6, TNFα, and NFkB1 in SM-ASCs in in-vitro and in-vivo settings confirmed its potential in promoting cell-proliferation, migration, angiogenesis, antioxidant, cell-survival, anti-inflammatory, and wound healing activity. Moreover, SM-ASCs induced early wound closure, better architecture, normal epidermal thickness, orderly-arranged collagen fibers, and well-developed skin appendages in healed rat-skin transplanted with AM+SM-ASCs, additionally confirmed by increased expression of structural genes (Krt1, Krt8, Krt19, Desmin, Vimentin, α-Sma) in comparison to untreated-ASCs laden-AM transplanted in heat injured rats. Conclusion: SM priming effectively enabled ASCs to counter thermal injury by significantly enhancing cell survival and reducing inflammation upon transplantation. This study provides bases for development of effective combinational therapies (natural scaffold, medicine, and stem cells) with clinical prospects for treating burn wounds. Background: Thermal traumas impose a huge burden on healthcare systems. This merits the need for advanced but cost-effective remedies with clinical prospects. In this context, we prepared a regenerative 3D-construct comprising of Cassia angustifolia extract (SM) primed adipose-derived stem cells (ASCs) laden amniotic membrane for faster burn wound repair. Methods: ASCs were preconditioned with SM (30 µg/ml for 24 h), and subsequently exposed to in-vitro thermal injury (51 °C,10 min). In-vivo thermal injury was induced by placing pre-heated copper-disc (2 cm diameter) on dorsum of the Wistar rats. ASCs (2.0 × 105) pre-treated with SM (SM-ASCs), cultured on stromal side of amniotic membrane (AM) were transplanted in rat heat-injury model. Non-transplanted heat-injured rats and non-heat-injured rats were kept as controls. Results: The significantly upregulated expression of IGF1, SDF1A, TGFβ1, VEGF, GSS, GSR, IL4, BCL2 genes and downregulation of BAX, IL6, TNFα, and NFkB1 in SM-ASCs in in-vitro and in-vivo settings confirmed its potential in promoting cell-proliferation, migration, angiogenesis, antioxidant, cell-survival, anti-inflammatory, and wound healing activity. Moreover, SM-ASCs induced early wound closure, better architecture, normal epidermal thickness, orderly-arranged collagen fibers, and well-developed skin appendages in healed rat-skin transplanted with AM+SM-ASCs, additionally confirmed by increased expression of structural genes (Krt1, Krt8, Krt19, Desmin, Vimentin, α-Sma) in comparison to untreated-ASCs laden-AM transplanted in heat injured rats. Conclusion: SM priming effectively enabled ASCs to counter thermal injury by significantly enhancing cell survival and reducing inflammation upon transplantation. This study provides bases for development of effective combinational therapies (natural scaffold, medicine, and stem cells) with clinical prospects for treating burn wounds.
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