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- 저자 : ( Razman Jarmin ) (검색결과 2 건)
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( Hairol Othman ),( Zamri Zuhdi ),( Azlanudin Azman ),( Chik Ian ),( Razman Jarmin ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Significant experience with biodegradable biliary stenting has been reported in the literature. The biodegradable stents are typically made from polymeric materials including Polylac tide (PLA) or Polyglycolide, which have been approved by the FDA and CE as drug carriers, sutures, and bone fixtures. We have embarked on a pilot study to assess the safety and feasi bility of a novel balloon expandable bioresorbable biliary stent. Methods: This is a prospective, pilot, open-label descriptive safety and feasibility study, conducted at UKM Medical Centre, Kuala Lumpur. Patients with benign biliary strictures were re cruited. Patients will be follow-up at interval period of weeks 1 and 2, months 1,3,6,9 and 12. The primary objective was to assess safety of the UNITY stent. The secondary objectives were clinical, technical and procedural success. The novel UNITY-B stent comprised of biodegradable magnesium alloy core with biodegradable polymer coating. It degrades through hydrolysis. Results: 6 patients has been recruited from 1 October 2017 until 30 April 2018. Among the indications include; 4 patients with type-2 benign distal common bile duct (CBD) stricture, 1 patient with post-cholecystectomy (Strasberg type E5) stricture, 1 patient with post-operative end-to-end common bile duct anastomotic stricture. At the primary safety endpoint within 30 days of the index procedure, all patients has remained symp tom free. Only one patient has reached 6 months follow-up. The secondary objectives were achieved in all 6 patients. Serum bilirubin dropped more than 20% at one week and remained low at 1 month in 5 patients. 1 patient did not show reduction in serum bilirubin but reported improvement in symptoms. 1 patient who has reached 6 month follow-up reported pruritus but has normal serum bilirubin. Conclusions: The UNITY stent has fulfil the safety criteria and has demonstrated good radial force to maintain patency of the stricturoplasty at 1 month. It is easy to be deployed and has the potential to replace the role of covered metal stents. None theless, this is an interim result of a small cohort of patients. A long term data on safety and efficacy of a larger number of patients is anticipated.
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Saim Hani Atiqah,Chik Ian,Jaafar Fahrol Fahmy,Zuhdi Zamri,Jarmin Razman,Azman Azlanudin 대한대장항문학회 2023 Annals of Coloproctolgy Vol.39 No.2
An Amyand’s hernia is characterised as the presence of the appendix in an inguinal hernial sac. During laparoscopic cholecystectomy for gallbladder polyps, an incidental Amyand’s hernia was discovered in a 75-year-old female patient. On examination, the hernia contained an appendiceal mucocele but no evidence of perforation. An open appendicectomy with tension-free mesh repair was performed for the hernia. The histopathological report of the appendix was a low-grade appendiceal mucinous neoplasm (LAMN), an entity that is just as rare as an Amyand’s hernia. The patient had the right inguinal swelling for over 10 years but it was thought to be an inguinal intramuscular cyst as reported on a previous abdominal ultrasound. Mucocele of the appendix may have a benign or malignant appendiceal progress, leading to individualised diagnosis and treatment. We review an Amyand’s hernia with LAMN and discuss the asymptomatic tendency yet malignant potential of appendiceal mucoceles along with treatment strategies.
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