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- 저자 : ( Rajaram Deepak Madi ) (검색결과 1 건)
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( Rajaram Deepak Madi ),( Sathish V ),( Basavaprabhu Achappa ),( Sathish Rao ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: Highly active antiretroviral therapy (HAART) is available free of cost in India as a part of our national ART programme since 2004.Early diagnosis and initiation of HAART are key components for the success of HIV control programmes. Late presentation with low baseline CD4 cell count is a strong prognostic marker for early mortality among HIV patients. The main aim of our study was to identify late presenters based on initial CD4 cell count testing. We also wanted to identify factors associated with late presentation. Methods: This retrospective hospital based study was carried out at Kasturba Medical College. The study group included 474 newly diagnosed HIV patients registered in the ART clinic of KMC between February 2012 and February2013. Subjects with CD4 T cell count below 200 cells per cubic millimetre were classifi ed as late presenters. Subjects with CD4 T cell counts less than 50 cells per cubic millimetre were termed as very late presenters. Statistical analysis was performed with SPSS software. Results: The mean age of our study population was 41.60±9.28years. Majority of our study population were males 327(69%). Median CD4 count at diagnosis was 188 cells per cubic millimetre ([IQR] 93-366 ). 208(44%) patients had WHO stage 4 disease at presentation. 251(53%) were late presenters and 223(47%) were early presenters. 47(9.9%) were very late presenters.Male gender(p=.03) and residing in rural area (p=.001) had a signifi cant positive association with late presentation. Conclusions: More than fi fty percent of patients were late presenters despite ART being available free of cost in India. Late presentation poses a signifi cant threat to the success of our national ART programme.HIV/AIDS care intervention programmes must target men and the rural population as they are vulnerable for late presentation as shown in our study.
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