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Efficient Scheme for Secret Hiding in QR Code by Improving Exploiting Modification Direction
( Peng-cheng Huang ),( Yung-hui Li ),( Chin-chen Chang ),( Yanjun Liu ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.5
QR codes as public patent are widely used to acquire the information in various fields. However, it faces security problem when delivering the privacy message by QR code. To overcome this weakness, we propose a secret hiding scheme by improving exploiting modification direction to protect the private message in QR code. The secret messages will be converted into octal digit stream and concealed to the cover QR code by overwriting the cover QR code public message bits. And the private messages can be faithfully decoded using the extraction function. In our secret hiding scheme, the QR code public message still can be fully decoded publicly from the marked QR codes via any standard QR Code reader, which helps to reduce attackers’ curiosity. Experiments show that the proposed scheme is feasible, with high secret payload, high security protection level, and resistant to common image post-processing attacks.
Efficient secret sharing scheme with cheater identification based on QR code
( Peng-cheng Huang ),( Chin-chen Chang ),( Yung-hui Li ),( Yanjun Liu ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.10
Secret sharing is an effective way of protecting secret messages. However, the traditional secret sharing schemes are considered meaningless due to malicious people attention which might raise risks. To overcome the weakness, this paper presents an effective secret sharing scheme with the functionality of cheater identification, based on meaningful QR code. The secret message will be split and concealed in the padding region of cover QR codes with the assistance of Latin square and it can be completely restored when all the involved participants cooperate. The concealing strategy exploits the characteristic of Reed-Solomon (RS) code to ensure the strong robustness of generated QR code pseudo-shares. The meaningful QR code pseudo-shares help to reduce the curious of unrelated persons. Some experiments were done to evaluate the performance of proposed scheme. The results showed that the proposed scheme is feasible, efficient and secure compared to the other existing schemes. It also achieves a higher secret payload and maintains stronger robustness.
Improved trajectory similarity-based approach for turbofan engine prognostics
Cheng-Geng Huang,Hong-Zhong Huang,Weiwen Peng,Tudi Huang 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.10
Trajectory similarity-based prediction (TSBP) is an emerging real-time remaining useful life (RUL) prediction method that has drawn considerable attention in the field of data-driven prognostics. TSBP is fast, and the corresponding model is easy to train. However, TBSP only provides a point estimation of RUL, which is insufficient for some specific prognostic applications. Hence, this study introduces an improved TSBP method to handle the issue of prognostic uncertainty. On the basis of an adaptive kernel density estimation technique and β-criterion, the improved TSBP method not only provides an accurate and precise point prediction of RUL but also specifies the confidence interval of RUL prediction. The capability of obtaining the confidence interval of RUL can enhance the TSBP method for uncertainty management. The effectiveness of the proposed method is validated through two cases studies, which are related to turbofan engine prognostics.
( Ming-lung Yu ),( Chao-hung Hung ),( Yi-hsiang Huang ),( Cheng-yuan Peng ),( Chun-yen Lin ),( Pin-nan Cheng ),( Rong-nan Chien ),( Shih-jer Hsu ),( Chen-hua Liu ),( Jee-fu Huang ),( Chung-feng Huang 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: The current study aims to elucidate the treatment efficacy (defined as undetectable HCV RNA throughout 12 weeks of post-treatment follow-up, SVR12) and safety DCV/ASV plus ribavirin for 12 weeks in HCV-1b patients without NS5A RAS. Methods: This is a single-arm, open-label phase 2 study. Seventy directly acting antivirals (DAA)-naïve HCV-1b patients without L31/Y93 RAS are planned to receive daclatasvir (60 mg/ day) and asunaprevir (100 mg twice daily) plus weight-based ribavirin (1000-1200 mg/day) for 12 weeks. After treatment they were followed up for 12 weeks. Results: As of 31 Oct 2017, 58 eligible patients are allocated to treatment, with a mean age of 59.3 years and female predominance (67.2%, 39/58). The mean HCV RNA was 5.87+0.77 log10 IU/mL; 23 patients (39.7 %) had significant hepatic fibrosis (>F2). In the modified intention-to-treat analysis, the rate of undetectable HCV at week 1, week 2, week 4, week 8 and endof- treatment was 25 % (14/56), 84.8 % (39/46), 100 % (46/46), 100 % (38/38) and 100 % (27/27), respectively. Undetectable HCV RNA were observed in all of the patients with HCV RNA assessable 4 weeks (SVR4, 18/18) and 12 weeks (SVR12, 12/12) post treatment. None of the 18 patients who completed the 12-week treatment experienced relapse during post-treatment follow-up. The most common adverse event was fatigue (78.3 %), followed by pruritus (65.2 %) and dizziness (52.2 %), of which were considered as ribavirin related. None of the participating subjects withdrew treatment or follow-up throughout the trial peroid. Three serious adverse events were reported which included urosepsis, appendicitis and left ureteral stone. All were unrelated to the investigating drugs. Conclusions: 12 weeks of DCV/ASV plus ribavirin was highly effective and safe in HCV-1b patients without NS5A RAS in the interim analysis. The satisfactory results would be anticipated in the full patient set.
Huang, Tao,Gong, Wei-Hua,Li, Xiu-Cheng,Zou, Chun-Ping,Jiang, Guang-Jian,Li, Xu-Hui,Feng, Dian-Peng Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1
Purpose: To study enhancing effects of paclitaxel in the thermochemotherapy of osteosarcoma cell lines and related mechanisms. Materials and Methods: Paclitaxel and carboplatin were used alone or jointly on OS732 cell lines in the presence of hyperthermia. Inhibition of proliferation was measured by MTT assay and cellular changes were assessed with inverted phase contrast and fluorescence microscopy. Apoptosis was analyzed with flow cytometry (FCM) and Fas expression by immunocytochemistry. Results: At $43^{\circ}C$, one hour after the application of 10ug/ml paclitaxel and $5{\mu}g/ml$ carboplatin on OS732 cells jointly, the survival rate was 15.8% which was significantly lower than with $10{\mu}g/ml$ paclitaxel (45.8%) and $5{\mu}g/ml$ carboplatin (47.7%) respectively (P<0.01). Moreover, changes of morphology and apoptotic rates indicated that the apoptosis-inducing effect of combined application was also much enhanced, as evident also regarding Fas expression. Conclusion: Paclitaxel is conducive to thermochemotherapy of osteosarcoma cell lines, possibly accomplished by up-regulation of Fas expression with induction of apoptosis.
Huang, Peng-Yi,Chen, Liang-Hsiang,Kim, Choongik,Chang, Hsiu-Chieh,Liang, You-jhih,Feng, Chieh-Yuan,Yeh, Chia-Ming,Ho, Jia-Chong,Lee, Cheng-Chung,Chen, Ming-Chou American Chemical Society 2012 ACS APPLIED MATERIALS & INTERFACES Vol.4 No.12
<P>Three benzo[<I>d</I>,<I>d</I>′]thieno[3,2-<I>b</I>;4,5-<I>b</I>′]dithiophene (<B>BTDT</B>) derivatives, end-functionalized with benzothiophenyl (<B>BT-BTDT</B>; <B>2</B>), benzothieno[3,2-b]thiophenyl (<B>BTT-BTDT</B>; 3), and benzo[<I>d</I>,<I>d</I>′]thieno[3,2-<I>b</I>;4,5-<I>b</I>′]dithiophenyl (<B>BBTDT</B>; <B>4</B>), were prepared for bottom-contact/bottom-gate organic thin-film transistors (OTFTs). An improved one-pot [2 + 1 + 1] synthetic method of <B>BTDT</B> with improved synthetic yield was achieved, which enabled the efficient realization of new <B>BTDT</B>-based semiconductors. All of the <B>BTDT</B> compounds exhibited high performance p-channel characteristics with carrier mobilities as high as 0.34 cm<SUP>2</SUP>/(V s) and a current on/off ratio of 1 × 10<SUP>7</SUP>, as well as enhanced ambient stability. The device characteristics have been correlated with the film morphologies and microstructures of the corresponding compounds.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2012/aamick.2012.4.issue-12/am3022448/production/images/medium/am-2012-022448_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am3022448'>ACS Electronic Supporting Info</A></P>
Role of miR-511 in the Regulation of OATP1B1 Expression by Free Fatty Acid
Peng, Jin Fu,Liu, Li,Guo, Cheng Xian,Liu, Shi Kun,Chen, Xiao Ping,Huang, Li Hua,Xiang, Hong,Huang, Zhi Jun,Yuan, Hong,Yang, Guo Ping The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.5
MicroRNAs (miRNAs) are a family of non-coding RNA that are able to adjust the expression of many proteins, including ATP-binding cassette transporter and organic cation transporter. We sought to evaluate the effect of miR-511 on the regulation of OATP1B1 expression by free fatty acids. When using free fatty acids to stimulate Chang liver cells, we found that the expression of miR-511 increased significantly while the expression of OATP1B1 decreased. We also proved that SLCO1B1 is the target gene of miR-511 with a bioinformatics analysis and using the dual luciferase reporter assay. Furthermore, the expressions of SLCO1B1 and OATP1B1 decreased if transfecting Chang liver cells with miR-511, but did not increase when transfecting the inhibitors of miR-511 into steatosis cells. Our study indicates that miR-511 may play an important role in the regulation of OATP1B1 expression by free fatty acids.
A Novel Image Dehazing Algorithm Based on Dual-tree Complex Wavelet Transform
( Changxin Huang ),( Wei Li ),( Songchen Han ),( Binbin Liang ),( Peng Cheng ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.10
The quality of natural outdoor images captured by visible camera sensors is usually degraded by the haze present in the atmosphere. In this paper, a fast image dehazing method based on visible image and near-infrared fusion is proposed. In the proposed method, a visible and a near-infrared (NIR) image of the same scene is fused based on the dual-tree complex wavelet transform (DT-CWT) to generate a dehazed color image. The color of the fusion image is regulated through haze concentration estimated by dark channel prior (DCP). The experiment results demonstrate that the proposed method outperforms the conventional dehazing methods and effectively solves the color distortion problem in the dehazing process.