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RISS 인기검색어
- 검색키워드
- 저자 : ( Lihua Pang ) (검색결과 3 건)
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Protective effect of liensinine on periodontitis through its antioxidant effect in mice
Pang, Liang,Zhu, Kai,Feng, Xia,Liu, Weiwei,Peng, Deguang,Qiu, Lihua,Gao, Xiang,Deng, Jiang,Li, Ying,Zhao, Xin 한국응용생명화학회 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.6
Liensinine is the most important functional compound in lotus seeds; its protective effect on periodontitis was determined and the mechanism of its antioxidant effect was also explained. During the experiment, we could observe that liensinine could reduce the gingival index in periodontitis-induced mice, and these effects were similar to that during the treatment of periodontitis with the metronidazole drug. After the treatment with liensinine, the serum Immunoglobulin G1 ($IgG_1$) level was found to increase and $IgG_{2a}$ level was found to decrease compared to the periodontitis control mice. Liensinine and metronidazole could increase the superoxide dismutase (SOD) serum levels in the periodontitis-induced mice, and both the drugs at the same concentration (200 mg/kg) showed similar SOD activities, which was found to increase. Liensinine also increased the oxidation-related factor of catalase (CAT), glutathione peroxidase, and decreased nitric oxide, malondialdehyde, and endothelin in the serum of mice, compared to the periodontitis control mice. The serum cytokine levels of Interleukin-6, tumor necrosis factor-${\alpha}$, and Interferon-${\gamma}$ in liensinine-treated mice were lower than the control mice, but higher than the normal mice. The serum IL-4 cytokine level of liensinine-treated mice was reversed, i.e., higher than the control mice. In the periodontal tissue, the mRNA and protein expressions of inhibitor of kappa B-${\alpha}$, trans-forming growth factor beta 1, Interleukin-10, Mn-SOD, Gu/Zn-SOD, and CAT were increased by the treatment with liensinine compared to the control group mice, and nuclear factor kappa B expressions showed the opposite trend. Liensinine is a good functional compound in the treatment of periodontitis, similar to metronidazole drug. Higher concentration of liensinine had better effects.
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Protective effect of liensinine on periodontitis through its antioxidant effect in mice
Liang Pang,Kai Zhu,Xia Feng,Weiwei Liu,Deguang Peng,Lihua Qiu,Xiang Gao,Jiang Deng,Ying Li,Xin Zhao 한국응용생명화학회 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.6
Liensinine is the most important functional compound in lotus seeds; its protective effect on periodontitis was determined and the mechanism of its antioxidant effect was also explained. During the experiment, we could observe that liensinine could reduce the gingival index in periodontitis-induced mice, and these effects were similar to that during the treatment of periodontitis with the metronidazole drug. After the treatment with liensinine, the serum Immunoglobulin G1 (IgG1) level was found to increase and IgG2a level was found to decrease compared to the periodontitis control mice. Liensinine and metronidazole could increase the superoxide dismutase (SOD) serum levels in the periodontitis-induced mice, and both the drugs at the same concentration (200 mg/kg) showed similar SOD activities, which was found to increase. Liensinine also increased the oxidationrelated factor of catalase (CAT), glutathione peroxidase, and decreased nitric oxide, malondialdehyde, and endothelin in the serum of mice, compared to the periodontitis control mice. The serum cytokine levels of Interleukin-6, tumor necrosis factor-a, and Interferon-c in liensinine-treated mice were lower than the control mice, but higher than the normal mice. The serum IL-4 cytokine level of liensinine-treated mice was reversed, i.e., higher than the control mice. In the periodontal tissue, the mRNA and protein expressions of inhibitor of kappa B-a, transforming growth factor beta 1, Interleukin-10, Mn-SOD, Gu/Zn-SOD, and CAT were increased by the treatment with liensinine compared to the control group mice, and nuclear factor kappa B expressions showed the opposite trend. Liensinine is a good functional compound in the treatment of periodontitis, similar to metronidazole drug. Higher concentration of liensinine had better effects.
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PSO-based Resource Allocation in Software-Defined Heterogeneous Cellular Networks
( Wenrong Gong ),( Lihua Pang ),( Jing Wang ),( Meng Xia ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.5
A heterogeneous cellular network (HCN) is useful to increase the spectral and energy efficiency of wireless networks and to reduce the traffic load from the macro cell. The performance of the secondary user equipment (SUE) is affected by interference from the eNodeB (eNB) in a macro cell. To decrease the interference between the macro cell and the small cell, allocating resources properly is essential to an HCN. This study considers the scenario of a software-defined heterogeneous cellular network and performs the resource allocation process. First, we show the system model of HCN and formulate the optimization problem. The optimization problem is a complex process including power and frequency resource allocation, which imposes an extremely high complexity to the HCN. Therefore, a hierarchical resource allocation scheme is proposed, which including subchannel selection and a particle swarm optimization (PSO)-based power allocation algorithm. Simulation results show that the proposed hierarchical scheme is effective in improving the system capacity and energy efficiency.
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