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- 저자 : ( Judith Alvarez Otero ) (검색결과 1 건)
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( Judith Alvarez Otero ),( Lucia Gonzalez Gonzalez ),( Jose Luis Lamas Ferreiro ),( Alexandra Arca Blanco ),( Jose Ramon Bermudez Sanjurjo ),( Maria Rodriguez Conde ),( Javier De La Fuente Aguado ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: The aim of this study was to analyze the prevalence of carbapenem resistant Pseudomonas aeruginosa (CRPA) in urine cultures in our hospital. Moreover, we determined the mortality and risk factors associated to CRPA infection. Methods: Positive urine cultures to Pseudomonas aeruginosa between september 2012 and september 2013 were identified. We excluded repititive cultures from the same patient and episode. We created a database with demographic, clinical and laboratory items, including previous antibiotic therapy and antimicrobial resistance. Results: Forty-three cases with positive urine cultures to Pseudomonas aeruginosa were included. CRPA was observed in 12cases, with a prevalence of 27.9%. Sixty per cent were male with a median age of 73 years (range: 17-102). Sixty-seven per cent of patients were hospitalized when the culture was collected, but only 30% met criteria to nosocomial infection. Twenty-one percent of urine cultures corresponded to asymptomatic bacteriuria and 25% presented with sepsis. Mortality at 30 days was 20.7% in CRPA patients and 13.8% in the other group, without estatistical significance. Obesity (p =0.003), previous treatment with ciprofloxacin (p = 0.004) and quinolones in general (p = 0.001) and previous treatment with more than one antibiotic (p = 0.03) or with more than one family of antibiotics (p = 0.01) were risk factors to CRPA infection in the univariate analysis. Only obesity (p = 0.04) and previous treatment with ciprofloxacin (p = 0.02) showed statistically significant differences in the multivariate analysis, Conclusions: There is a high prevalence of CRPA in urine cultures in our population, wich is a potencial threat. We should assess the presence of risk factors for development of infections by such pathogen, as previous treatment with quinolones or obesity, in order to start appropiate empirical treatment in patients with severe urinary tract infections.
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