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        Geopolitics and Regionalism : China`s New Silk Road: Where Does It Lead?

        ( Gan Jun Xian ),( Mao Yan ) 경남대학교 극동문제연구소 2016 ASIAN PERSPECTIVE Vol.40 No.1

        We analyze the driving forces behind China’s New Silk Road (NSR) initiative and find that they not only included short-term factors, such as the US “rebalance” of forces in Asia and China’s economic slowdown since 2012, but also long-term factors such as China’s ambition to recover its past glory and integrate itself still further into the global economy. We then look at the external challenges facing China’s initiative, such as geopolitical competition, fear of overdependence, and political instabilities along the old silk routes. We highlight China’s policy dilemmas and discuss the sustainability of China’s NSR initiative and its implications for the world. Our conclusion is that China’s initiative could be in for a rocky road, but if it strikes a good balance between its diplomatic objectives and means and its values and actions, the NSR could speed up regional integration. KEYWORDS: China, the New Silk Road, geopolitical conflicts, regional integration.

      • X-Ray Repair Cross-Complementing Group 1(XRCC1) Genetic Polymorphisms and Thyroid Carcinoma Risk: a Meta-Analysis

        Qian, Ke,Liu, Kui-Jie,Xu, Feng,Chen, Xian-Yu,Chen, Gan-Nong,Yi, Wen-Jun,Zhou, En-Xiang,Tang, Zhong-Hua Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

        A number of studies have been conducted to explore the association of XRCC1 polymorphisms with thyroid cancer risk, but the results have been inconsistent. Thus we performed the present meta-analysis to clarify this issue based on all of the evidence available to date. Relevant studies were retrieved by searching PubMed and statistical analysis conducted using Stata software. Nine studies were included in this meta-analysis (1,620 cases and 3,557 controls). There were 6 studies (932 cases and 2,270 controls) of the Arg194Trp polymorphism, 7 studies (1432 cases and 3356 controls) of the Arg280His polymorphism and 9 studies (1,620 cases and 3,557 controls) for the Arg399Gln polymorphism. No association of XRCC1 Arg194Trp, Arg280His and Arg399Gln polymorphism with thyroid cancer risk was observed in the overall analysis. However, subgroup analysis revealed: 1) an elevated risk in aa vs AA analysis (OR=2.03, 95%CI= 1.24-3.31) and recessive genetic model analysis (OR=1.93, 95%CI= 1.20-3.08) in the larger sample size trials for XRCC1 Arg194Trp polymorphism; 2) a decreased thyroid cancer risk on subgroup analysis based on ethnicity in Aa vs AA analysis (OR=0.84, 95%CI= 0.72-0.98) and in a dominant genetic model (OR=0.84, 95%CI= 0.72-0.97) in Caucasian populations for the XRCC1 Arg399Gln polymorphism; 3) a decreased thyroid cancer risk on subgroup analysis based on design type in Aa vs AA analysis (OR=0.72, 95% CI= 0.54-0.97) among the PCC trials for the Arg399Gln polymorphism. Our results suggest that the XRCC1 Arg399Gln polymorphism may be associated with decreased thyroid cancer risk among Caucasians and XRCC1 Arg194Trp may be associated with a tendency for increased thyroid cancer risk in the two larger sample size trials.

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