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      • Analysis and Optimizing Method of Transient Performance for LCL-Based Grid-connected Inverter with Passive Damping

        Minghan. Dong,Hao. Ma,Zhihong. Bai 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        Dynamic currents and voltages in power electronic converters often exceed rating when changing load. In this way, this paper researches on optimizing transient performance of LCL-type gird-connected inverter systems. Resistor connected in series with capacitor as passive damping (RCSCPD), which is widely used to damp resonance of LCL filter, needs to choose an appropriate resistor to acquire accurate and fast transient performance. To meet this requirement, an approach is proposed for analyzing and improving transient performance. It shows that passive resistor could damp resonance and stable system. Limitation of RCSCPD, which could not optimize dominant transient response, is exhibited as well. Hence, mix damping (MD) is proposed to achieve the goal. It could eliminate overshoot and decrease settling time efficiently when comparing with RCSCPD. MD could configure the poles effectively without adding precision sensors because it uses grid current, which used in control loop, to realize active damping resistor. Experimental results based on single-phase LCL-type gird-connected inverter prototype are given to show optimizing effects of transient performance.

      • KCI등재

        Molecular cloning of novel α-gliadin genes from Crithopsis delileana and the evolution analysis with those from Triticeae

        Zhi-Fu Guo,Xiang-Yu Long,Pan Dong,Yu-Ming Wei,Li-Ping Bai,Xiao-Xuan Dang,Hao-Lei Wan,Li-Jun Zhang,You-Liang Zheng 한국유전학회 2011 Genes & Genomics Vol.33 No.2

        The α-gliadins from Crithopsis delileana (Schult) Roshev (2n=2x=14, KK) were investigated by Acid polyacrylamide gel electrophoresis (A-PAGE) analysis. It was indicated that the electrophoresis mobility of gliadins from C.delileana had obvious difference with those from common wheat in α, γand ω region. Using primers designed from published sequences of α-gliadin genes, three α-gliadin genes were isolated from C. delileana, which were designated as gli-ka1,gli-ka2 and gli-ka3, respectively. Two in-frame stop codons were found in the coding sequences of gli-ka3, indicating that gli-ka3 could be a pseudogene. The gli-ka2 was a gliadin with an odd number of cysteines, resulting from a non-synonymous mutation. This change might lead to the interactive behavior of gli-ka2. Three α-gliadin genes of C. delileana had the similar but not identical primary structures to the corresponding gene sequences from other wheat related species. By the alignment of α-gliadin genes from Triticeae,phylogenetic analysis indicated that three α-gliadin genes of C. delileana clustered together with all α-gliadin genes from Ee genome of Lophopyrum elongatum by an interior paralleled branch.

      • SCIESCOPUSKCI등재

        Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay

        ( Bin Xiao ),( Dan-dan Li ),( Ying Wang ),( Eun La Kim ),( Na Zhao ),( Shang-wu Jin ),( Dong-hao Bai ),( Li-dong Sun ),( Jee H. Jung ) 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.5

        In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib to the ligand-binding domain of PPAR-γ showed high binding affinity and relevant binding conformation compared with the PPAR-γ ligand/antidiabetic drug rosiglitazone. Per the docking result, parecoxib showed the best PPAR-γ transactivation in Ac2F rat liver cells. Further docking simulation and a luciferase assay suggested parecoxib would be a selective (and partial) PPAR-γ agonist. PPAR-γ activation by parecoxib induced adipocyte differentiation in 3T3-L1 murine preadipocytes. Parecoxib promoted adipogenesis in a dose-dependent manner and enhanced the expression of adipogenesis transcription factors PPAR-γ, C/EBPα, and C/EBPβ. These data indicated that parecoxib might be utilized as a partial PPAR-γ agonist for drug repositioning study.

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