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      저자 : ( Choun Gil Sohn ) (검색결과 1 건)
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      • Endoscopy and Imaging Modalities/Basic Science of Gastrointestinal Disorders/Miscellaneous : Optimal Number Of Endoscopic Biopsy In The Diagnosis Of Advanced Gastric And Colorectal Cancer

        ( Hyo Sun Choi ),( Choun Gil Sohn ),( Dong Il Park ),( Jung Ho Park ),( Woo Kyu Jeon ),( Byung Il Kim ),( Yong Kyun Cho ) 대한소화기학회 2007 SIDDS Vol.9 No.-

        Background/Aims: Endoscopic biopsy is necessary to confirm histopathologic diagnosis. Until now, six to eight biopsies were recommended for optimal diagnosis. Multiple biopsies may produce some problems such as increased risk of bleeding and increased workload to endoscopists, pathologists, and even to patients. The aim of this study was to clarify the optimal number of endoscopic biopsy specimens in the diagnosis of advanced gastric and colonic cancer. Methods: Patients who were diagnosed as advanced gastric or colon cancer endoscopically and pathologically in our hospital were included in this study. Seven biopsy specimens were obtained in serial number, five from the viable tissue of cancer margin and two from the ulcer debris during the endoscopy. An experienced pathologist evaluated each specimen and diagnosed. Results: A total 89 patients were enrolled, 59 advanced gastric cancer patients and 30 advanced colon cancer patients. The positive diagnosis rate of first specimen was 80.9%, and cumulative rates of second and third one were 92.1% and 96.6%. Further additional biopsy did not increase and cumulative rates of pathologic diagnosis. Positive diagnosis rates form the ulcer debris were relatively low, 60.7% and 59.6% and cumulative diagnostic yield was 71.9%. Conclusions: To make diagnosis pathologically in advanced gastric or colon cancer, three biopsy specimens were enough. Further biopsy did not make additional diagnostic yield. We recommend three or four biopsies from the viable tissue in advanced gastric or colon cancer to make efficacious diagnosis and reduce complications.

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