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( Alina Martynova ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Despite of the gained results in diagnostics and treatment of community- acquired pneumonias (CAP) the pneumococcal infection remains one of the leadingproblems of the modern medicine. Also there are still some discussions in epidemiological peculiarities of pneumococcal CAP in different age groups. The aim was to defi ne role of S. pneumoniae in ethiology. Methods: Our patients with confirmed CAP (400 patients) were divided on 4 age groups of 1-5 years, 6-15 years, adults (18-54), aged adults (55Results: pneumococcus was the leading pathogen in all age groups, and it was the most frequent in 1-5 children (42%), 6-15 (30%), 18-54 (35%), >55 years (60%). In some cases it was defi ned in association with the Chlamydia pneumophilla, Mycoplasma pneumonia and Haemophilus infi uenzae. The resistance of pneumcoocci to macrolides was in all groups, and it was connected with the spread of the mefE and ermB determinants, and there were only 12 penicilline resistant strains. The isolates were distributed among four major serotypes: 23F, 14, 18C, 6B. MLST (30 isolates) showed the spread of sequence types 90, 189, 240 and some others. Conclusions: Pneumococci remains the leading pathogen causing CAP in all age groups, and the epidemiological surveillance with molecular epidemiology study should be the fi rst step for preventive measures and the spread of the pneumococcal vaccines (e. g. Prevnar) among population.