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Changes of guidelines diagnosing hepatocellular carcinoma during the last ten-year period
Song, Do Seon,Bae, Si Hyun The Korean Association for the Study of the Liver 2012 Clinical and Molecular Hepatology(대한간학회지) Vol.18 No.3
<P>Hepatocellular carcinoma (HCC) is the third most common cause of cancer deaths in the world. There have been many advances in the diagnosis of HCC during the last ten years, especially in the imaging techniques. The Korean Liver cancer study group (KLCSG), European Association for the Study of the Liver (EASL), American Association for the Study of Liver disease (AASLD), and Asian-Pacific Association for the Study of Liver (APASL) have made and changed the HCC guidelines with the advances in the imaging techniques and according to the results of the researches on HCC. We reviewed the changes of the imaging guidelines in HCC diagnosis according to the advances in the imaging techniques. Further studies will be necessary to resolve the controversies in the diagnosis of HCC smaller than 1 cm in size.</P>
Etiologic and Laboratory Analyses of Ascites in Patients who Underwent Diagnostic Paracentesis
Hwangbo, Y.,Jung, J.H.,Shim, J.,Kim, B.-H.,Jung, S.H.,Lee, C.K.,Jang, J.Y.,Dong, S.H.,Kim, H.J.,Chang, Y.W. KOREAN ASSOCIATION FOR THE STUDY OF THE LIVER 2007 Clinical and Molecular Hepatology(대한간학회지) Vol.13 No.2
Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
Kang, Tae Wook,Lim, Hyo Keun,Cha, Dong Ik The Korean Association for the Study of the Liver 2017 Clinical and Molecular Hepatology(대한간학회지) Vol.23 No.1
<P>Image-guided radiofrequency ablation (RFA) is an evolving and growing treatment option for patients with hepatocellular carcinoma (HCC) and hepatic metastasis. RFA offers significant advantages as it is less invasive than surgery and carries a low risk of major complications. However, serious complications, including aggressive tumor recurrence, may be observed during follow-up, and recently, mechanical or thermal damage during RFA has been proposed to be one of the causes of this kind of recurrence. Although the exact mechanism of this still remains unclear, physicians should be familiar with the imaging features of aggressive tumor recurrence after RFA for HCC and its risk factors. In addition, in order to prevent or minimize this newly recognized tumor recurrence, a modified RFA technique, combined RFA treatments with transarterial chemoembolization, and cryoablation can be used as alternative treatments. Ultimately, combining an understanding of this potential complication of RFA with an understanding of the possible risk factors for aggressive tumor recurrence and choosing alternative treatments are crucial to optimize clinical outcomes in each patient with HCC.</P>
Park, Yun Ji,Lee, Sang Yeon,Kim, Seong Hun,Kim, In Hee,Kim, Sang Wook,Lee, Seung Ok The Korean Association for the Study of the Liver 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3
<P>Therapeutic paracentesis is considered to be a relatively safe procedure and is performed commonly for the control of massive ascites in patients with liver cirrhosis. The commonest puncture site, approximately 4 or 5 cm medial of left anterior superior iliac spine, can be located across the route of the inferior epigastric artery, which is one of the sites of potential massive bleeding. In a 46-year-old woman with liver cirrhosis and refractory ascites, a huge abdominal wall hematoma developed after therapeutic paracentesis. The patient was not stabilized by conservative treatment, and inferior epigastric artery injury was confirmed on angiography. Angiographic coil embolization of the inferior epigastric artery was conducted, after which the bleeding ceased and the hematoma stopped growing. This case indicates that physicians performing paracentesis should be aware of the possibility of inferior epigastric artery injury and consider early angiographic coil embolization when a life-threatening abdominal wall hematoma develops.</P>