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Bioactive glass-based nanocomposites for personalized dental tissue regeneration
Lee, Jung-Hwan,Seo, Seog-Jin,Kim, Hae-Won JAPANESE SOCIETY FOR DENTAL MATERIALS AND DEVICES 2016 Dental materials journal Vol.35 No.5
<P>Bioactive glass nanoparticles (BGNs) have been used over a range of dental tissue engineering. One main reason is possibly that BGNs strongly interact with hard tissues, while forming a stable interface after implantation. Recently, BGNs have been further diversified and ameliorated by incorporating bio-functional ions into BGNs or by functionally modifying the surface of BGNs. A comprehensive overview of the processes and applications of BGNs and their derivatives for the use in dentistry is thus necessary for their step forward. Therefore, this review focuses on a variety of processes and practical applications of BGNs and their derivatives, which is expected to aid readerships with understanding and employing BGNs and their derivatives for personalized dental treatments.</P>
Park, Hee Chul,Quan, Hongxuan,Yang, Hyeong-Cheol JAPANESE SOCIETY FOR DENTAL MATERIALS AND DEVICES 2017 Dental materials journal Vol.36 No.1
<P>Phosphatidylserine (PS) is known to enhance biomineraliration due to the ability to accumulate calcium ions. In this study, the effects of PS on odontogenic differentiation and mineralisation of human dental pulp cells (HDPCs) were investigated using phosphatidylserine-containing liposomes (PSLs): PSL was slightly cytotoxic at 125 mu M in growth medium, and ALP activity was up-regulated in the PSL-treated HDPCs at non-cytotoxic concentrations. Mineralisation was also enhanced by PSL, while mRNA expressions of DSPP and OCN genes were slightly attenuated. The mRNA expression of Runx2 was not altered by PSL. It is thus likely that PSL selectively affected odontogenic differentiation processes of HDPC. Finally, the interaction between PSL and HDPC was investigated by staining with annexin V-FITC in PSL-treated HDPC. It was found that PS was gradually incorporated into HDPC cytoplasm for several days. The results of this study suggest that PSL is able to stimulate dentin formation in dental pulps.</P>
Chlorhexidine-releasing orthodontic elastomerics.
Jeon, Hyun-Sun,Choi, Choong-Ho,Kang, Si-Mook,Kwon, Ho-Keun,Kim, Baek-Il Japanese Society for Dental Materials and Devices 2015 Dental materials journal Vol.34 No.3
<P>The aim of this study was to identify the best combination of chlorhexidine (CHX) with orthodontic elastomerics for prevention of oral disease in orthodontic patients. We used ethyl cellulose (EC) as the polymer, and experimental groups were divided into five groups according to differences in solvent (i.e., ethanol; EtOH, dichloromethane; DCM). CHX release from the coated elastomerics was evaluated with a UV spectrophotometer and observed by scanning electron microscope (SEM). The antimicrobial release increased over time for 48 h in Group 3 (CDA+EC+30% EtOH/70% DCM), exhibiting the longest sustained-release characteristics (p<0.001). It also showed the highest antimicrobial properties, which was confirmed by inhibition zone testing using S. mutans (p<0.05). All groups were not affected when tensile force was tested in the coated elastomerics. We conclude that the antibacterial effect of CHX can be adjusted according to combinations of polymers and solvents. Group 3 exhibited the best substantivity and antimicrobial properties.</P>
Jeon, Jin-Hun,Jung, Il-Do,Kim, Ji-Hwan,Kim, Hae-Young,Kim, Woong-Chul Japanese Society for Dental Materials and Devices 2015 Dental materials journal Vol.34 No.5
<P>In this study, we evaluated the repeatability of scans of stone models and impressions of abutment teeth using a blue LED scanner and compared the findings between different abutment teeth types. For the stone models as well as impression of the canines, premolars, and molars, we generated 10 color-difference-maps and reports for each tooth type (n=10 per tooth type). One-way analysis of variance (ANOVA) and independent t-tests were performed to evaluate the repeatability of scans of the stone models and impressions obtained from a blue LED scanner. Our results indicate a high repeatability of scans of stone models and impressions of abutment teeth using the blue LED scanner and suggest a possible clinical advantage for scanning impressions of different abutment teeth types.</P>
Uhm, Soo-Hyuk,Kim, Jae-Hong,Jiang, Heng Bo,Woo, Chang-Woo,Chang, Minho,Kim, Kyoung-Nam,Bae, Ji-Myung,Oh, Seunghan JAPANESE SOCIETY FOR DENTAL MATERIALS AND DEVICES 2017 Dental materials journal Vol.36 No.1
<P>The aims of this study were to evaluate the feasibility of 70% reduced inlay and 4-unit bridge models of International Standard (ISO 12836) assessing the accuracy of laboratory scanners to measure the accuracy of intraoral scanner. Four intraoral scanners (CS3500, Trios, Omnicam, and Bluecam) and one laboratory scanner (Ceramill MAP400) were used in this study. The height, depth, length, and angle of the models were measured from thirty scanned stereolithography (STL) images. There were no statistically significant mean deviations in distance accuracy and precision values of scanned images, except the angulation values of the inlay and 4-unit bridge models. The relative errors of inlay model and 4-unit bridge models quantifying the accuracy and precision of obtained mean deviations were less than 0.023 and 0.021, respectively. Thus, inlay and 4-unit bridge models suggested by this study is expected to be feasible tools for testing intraoral scanners.</P>
The effects of restorative composite resins on the cytotoxicity of dentine bonding agents.
Kim, Kyunghwan,Son, Kyung Mi,Kwon, Ji Hyun,Lim, Bum-Soon,Yang, Hyeong-Cheol Japanese Society for Dental Materials and Devices 2013 Dental materials journal Vol.32 No.5
<P>During restoration of damaged teeth in dental clinics, dentin bonding agents are usually overlaid with restorative resin composites. The purpose of this study was to investigate the effects of restorative resin composites on cytotoxicity of dentin bonding agents. Dentin bonding agents were placed on glass discs, pre-cured and uncured resin composite discs. Bonding agents on the glass discs and composite resins discs were light cured and used for agar overlay cytotoxicity testing. Dentin bonding agents on composite resin discs exhibited far less cytotoxicity than that on glass discs. The polymerization of resin composite increased the surface hardness and decreased the cytotoxicity of bonding agents. In conclusion, composite resins in dental restorations are expected to enhance the polymerization of dentin bonding agents and reduce the elution of resin monomers, resulting in the decrease of cytotoxicity.</P>
Yu, Sang-Hui,Ahn, Dae-Hyung,Park, Ji-Su,Chung, Yong Sik,Han, In-Sik,Lim, Jung-Seop,Oh, Seunghan,Oda, Yutaka,Bae, Ji-Myung Japanese Society for Dental Materials and Devices 2013 Dental materials journal Vol.32 No.2
<P>The aim of this study was to evaluate the effect of reinforcing polyaromatic polyamide (aramid) fibers with various orientations on the flexural properties of denture base resin. Aramid fibers with four orientations of unidirectional, woven, non-woven and paper-type were pre-impregnated and placed at the bottom of a specimen mold. Heat-polymerized denture base resin was packed over the fibers and polymerized. A three-point bending test was performed using a universal testing machine at a crosshead speed of 5 mm/min. The flexural strengths and flexural moduli of the unidirectional and woven groups were significantly higher than those of the control and other experimental groups.For the flexural moduli, all experimental groups showed significantly higher reinforcing effects than the control group. In conclusion, the unidirectional group located perpendicular to the direction of the load was most effective in reinforcing the denture base resin, followed by the woven group.</P>
Kim, Hong-Kyun,Woo, Kyung Mi,Shon, Won-Jun,Ahn, Jin-Soo,Cha, Seunghee,Park, Young-Seok JAPANESE SOCIETY FOR DENTAL MATERIALS AND DEVICES 2015 Dental materials journal Vol.34 No.4
<P>The aim of this study was to compare osseointegration and surface characteristics of zirconia implants made by the powder injection molding (PIM) technique against those made by the conventional milling procedure in rabbit tibiae. Surface characteristics of 2 types of implants were evaluated. Sixteen rabbits received 2 types of external hex implants with similar geometry, either machined zirconia implants or PIM zirconia implants, in the tibiae. Removal torque tests and histomorphometric analyses were performed. The roughness of the PIM zirconia implants was higher than that of machined zirconia implants. The PIM zirconia implants exhibited significantly higher bone-implant contact and removal torque values than the machined zirconia implants (p<0.001). The osseointegration of the PIM zirconia implant is promising, and PIM, using the roughened mold etching technique, can produce substantially rougher surfaces on zirconia implants.</P>
Influence of light-curing units on the polymerization of low-shrinkage composite resins.
Lee, Sang-Kyu,Kim, Tae-Wan,Son, Sung-Ae,Park, Jeong-Kil,Kim, Jong-Hwa,Kim, Hyung-Il,Kwon, Yong Hoon Japanese Society for Dental Materials and Devices 2013 Dental materials journal Vol.32 No.5
<P>This study examined the effect of various light-curing units (LCUs) on the polymerization of low-shrinkage composite resins. Two different types of low-shrinkage composite resins (silorane-based and methacrylate-based) were light cured using a quartz-tungsten-halogen (QTH) (HX) unit, a single-peak light-emitting diode (LED) (DM) unit, and a dual-peak LED (GL) unit, respectively. Among the tested LCUs, HX showed the lowest light attenuation within the specimens. Among the specimens, Aelite LS and Venus Diamond showed the highest and lowest light attenuation, respectively. Silorane-based Filtek LS showed the highest degree of conversion both on the top and bottom surfaces. On the bottom surface, Grandio and Aelite LS showed the lowest (4.5-7.1%) and highest (25.0-40.0%) decrease in the degree of conversion compared to their top surface. For different LCUs, within the same resin product, the microhardness was significantly different. The silorane-based composite resin showed significantly less polymerization shrinkage than the methacrylate-based nanofiller-containing composite resins.</P>