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Design, Fabrication and Vision Based Operational Analysis of Novel Shape Memory Alloy Micro Grippers
Özgür Yurtsever,Haluk Küçük 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.21 No.9
Object grip, grasp, hold and place type of tasks incorporate specific engineering design concepts. Considering such principals, eight gripper mechanisms were designed and produced which can be classified as micro grippers due to their small workspace, precise grasping and holding abilities. Common characteristics of all the designs are that, without using any electric motor, the open–close operation is by virtue of shape-memory alloys. Each gripper is designed for different purposes with different operational principles of which four were initially open and the other four were initially closed configurations. Parametric studies were performed by changing the duty cycle and frequency of pulse width modulation using a signal generator followed by measurement of gripper jaw clearance, open–close period, average open–close velocities, gripping force, holding and lifting abilities of the designed gripper mechanisms. Jaw displacement and velocity parameters were computed by image processing of video records captured during the operation of the gripper mechanisms.
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TORSIONAL RESONANCE MODE ATOMIC FORCE MICROSCOPY OF A PROTEIN–DNA COMPLEX
GILBERTO WEISSMÜLLER,AYHAN YURTSEVER,LILIAN T. COSTA,ANA B. F. PACHECO,PAULO M. BISCH,WOLFGANG M. HECKL,ROBERT W. STARK 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2008 NANO Vol.3 No.6
Precise mapping of protein-binding sites on DNA is an important application of atomic force microscope (AFM) imaging. For a reliable measurement of distances on curved DNA molecules, an image-processing algorithm is required, which extracts the DNA contour from topographic AFM data. To this end we implemented an image analysis method providing an efficient way to obtain the contour together with a physical map of single and multiple protein-binding sites. This method relies on a calculation of the height profile along the DNA fragment, allowing one to determine the DNA length and the relative position of the binding site occupied by a protein. As a first test, complexes of the LexA repressor protein from the Escherichia coli SOS system and DNA fragments containing a specific LexA binding site (recA operator) were imaged by the torsional resonance mode (TR mode) and analyzed using the specialized algorithm. A topographic height of less than 0.5 nm of the DNA molecules indicates repulsive imaging conditions.
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The Quality of Life in Patients With Behçet’s Disease
Özlem Canpolat,Sabire Yurtsever 한국간호과학회 2011 Asian Nursing Research Vol.5 No.4
Purpose: This study aims to evaluate the quality of life (QoL) in patients with Behçet’s disease. Methods: This study is a cross-sectional descriptive study. The sample of the study consists of 94volunteer patients, who were diagnosed with Behçet’s disease at least 3 months before the study, were literate, and never diagnosed with a psychiatric illness. Short Form-36 QoL Scale and personal information form were used to collect data. The mean, percentage distribution of the sample were calculated;one-way analysis of variance, student t test, Mann-Whitney U, Kruskal Wallis, Shapiro-Wilk tests were used to evaluate the data. Results: It was found that QoL scores in patients with Behçet’s disease were low and wasaffected by gender, age, work status, education status as well as complaints of oral and genital ulcerations, arthritis,skin lesions and bodily pain. Patients who were suffering from bodily pain, sleeplessness and fatigue were found to score lower in the QoL scale. Moreover, patients who states that their social relationships are affected by the disease had significantly lower QoL scores. Conclusion: The need for evaluating the patients holistically and of the planning of their care were highlighted.
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Erol Yildirim,Gokhan Erciyes,Mine Yurtsever 한국고분자학회 2013 Macromolecular Research Vol.21 No.9
Poly(ε-caprolactone) grafted polypyrroles (PPy-g-PCL) are an important member of hairy-rod copolymers which have many industrial applications. PPy-g-PCL cooligomers were studied for their electronic, structural and morphological properties by density functional theory (DFT), molecular dynamics and mesoscale dynamics simulation methods. The band gaps of the cooligomers were calculated at the B3LYP/6-31g(d,p) level by varying the grafting position of PCL group. UV spectra was studied by time-dependent DFT methods. The solubility parameters and interaction parameters between the PCL and PPy were calculated via molecular dynamics simulations. The morphological behaviors were studied by the molecular dynamics and dissipative particle dynamics (DPD) methods to understand the role of rigidity of polypyrrole backbone, the chain lengths of PPy and PCL and the incompatibility of the polymers on the formation of layered phase domains observed experimentally for high weight percentages of PCL side chains.
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Kum, Rauf Oguzhan,Ozcan, Muge,Baklaci, Deniz,Kum, Nurcan Yurtsever,Yilmaz, Yavuz Fuat,Gungor, Volkan,Unal, Adnan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17
Background: Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. Despite extensive research, reliable markers with diagnostic and prognostic value are still lacking. It was recently reported that an elevated preoperative neutrophil-to-lymphocyte ratio (NLR) may correlate with an increased risk of recurrence, tumor aggressiveness and poorer prognosis in various malignancies. The aim of this study was to examine whether NLR could be used as an inflammatory marker to differentiate laryngeal squamous cell carcinoma (LSCC) patients from benign laryngeal lesion (BLL) and precancerous laryngeal lesion (PLL) patients. Materials and Methods: This retrospective study was performed on 209 patients admitted to a tertiary referral center with laryngeal lesions and undergoing biopsies to establish their histopathological diagnosis. We reviewed the patient files for their clinical, histopathological and laboratory data. The patients were divided into three groups according to their histopathological findings, as BLL, PLL and LSCC groups. The patients in the PLL group were also divided into three subgroups as mild, moderate and severe dysplasia/carcinoma in situ (CIS) subgroups. The groups were compared for NLR and the other laboratory data. Results: The mean NLRs of the BLL, PLL and the LSCC groups were $2.12{\pm}0.86$, $2.32{\pm}0.68$ and $3.46{\pm}1.51$, respectively, and the difference was statistically significant (p=0.001). The mean NLRs of the patients with PLL and LSCC were significantly higher than the patients with BLL (p=0.031 and p=0.001, respectively). The mean NLRs were similar among mild dysplasia, moderate dysplasia and severe dysplasia / CIS groups (p>0.05). Conclusions: To our knowledge, this is the first study investigating NLR in BLL, PLL and LSCC. NLR is an inexpensive, reproducible and widely available blood test, and could be a useful inflammatory marker to differentiate LSCC from BLL and PLL.
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