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- 저자 : Yunhong Song (검색결과 2 건)
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Anesthetic Management in a Patient with a Tracheal Diverticulum: A Case Report
( Keulame Song ),( Jia Kim ),( Kyoungho Ryu ),( Eunah Cho ),( Wonjun Choi ),( Yunhong Kim ),( Hyunsoo Kim ) 경희대학교 경희의료원 2017 慶熙醫學 Vol.32 No.1
Tracheal diverticulum (TD) could cause difficult tracheal intubation or ventilation. It is also associated with critical complications such as pneumomediastinum during general anesthesia. We report successful anesthetic management of a patient with a TD using a flexible fiberoptic bronchoscope. A 70-year-old man was scheduled for laparoscopic colorectal surgery. Preoperative chest computed tomography revealed the TD located 7 cm cephalad to the carina. To confirm the location of the TD, bronchoscope-guided tracheal intubation was planned. After induction of general anesthesia, the location of the TD was confirmed using a bronchoscope and a 7.5-mm inner diameter endotracheal tube was advanced distally more than the standard position so that the balloon of the endo tracheal tube could pass beyond the opening of the TD. This process enabled isolation of the TD from the positive pressure of mechanical ventilation. The surgery was subsequently completed with no ventilatory disturbance or hemodynamic instability.
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Jingyuan Guan,Xiao Xiao,Shengjuan Xu,Fen Gao,Jianbo Wang,Tietao Wang,Yunhong Song,Junfeng Pan,Xihui Shen,Yao Wang 한국미생물학회 2015 The journal of microbiology Vol.53 No.9
RpoS (σS), the stationary phase/stress σ factor, controls the expression of a large number of genes involved in cellular responses to a variety of stresses. However, the role of RpoS appears to differ in different bacteria. While RpoS is an important regulator of flagellum biosynthesis, it is associated with biofilm development in Edwardsiella tarda. Biofilms are dense communities formed by bacteria and are important for microbe survival under unfavorable conditions. The type VI secretion system (T6SS) discovered recently is reportedly associated with several phenotypes, ranging from biofilm formation to stress sensing. For example, Vibrio anguillarum T6SS was proposed to serve as a sensor for extracytoplasmic signals and modulates RpoS expression and stress response. In this study, we investigated the physiological roles of RpoS in Yersinia pseudotuberculosis, including bacterial survival under stress conditions, flagella formation, biofilm development and T6SS expression. We found that RpoS is important in resistance to multiple stressors–including H2O2, acid, osmotic and heat shock–in Y. pseudotuberculosis. In addition, our study showed that RpoS not only modulates the expression of T6SS but also regulates flagellum formation by positively controlling the flagellar master regulatory gene flhDC, and affects the formation of biofilm on Caenorhabditis elegans by regulating the synthesis of exopolysaccharides. Taken together, these results show that RpoS plays a central role in cell fitness under several adverse conditions in Y. pseudotuberculosis.
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