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      • KCI등재

        Acetabular, Femoral, and Combined Anteversion in a Province in South Korea: Computed Tomography-Based Study

        Youngho Cho,Jaeuk Shin,Sangwoo Kim 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.4

        Background: The purpose of this study was to investigate the femoral, acetabular, and combined anteversion of the hip joint in South Koreans using computed tomography (CT). Methods: We measured anteversion using CT venograms taken from 2016 to 2020. Of the total 1,073 patients, 952 patients were included in the study except for those with pelvic fractures, previous femoral fractures, childhood hip joint disease, osteoarthritis, or hip dysplasia (lateral center-edge angle, < 20), foreigners, and hip and knee replacement patients. Measurements were taken twice by two orthopedic surgeons. Results: The femoral anteversion in women was 10.64° ± 10.26° (≤ 49 years), 15.75° ± 9.40° (50–59 years), 10.81° ± 9.14° (60–69 years), 12.38° ± 8.55° (70–79 years), and 11.23° ± 8.44° (≥ 80 years). The femoral anteversion in men was 12.02° ± 11.38° (≤ 49 years), 10.62° ± 9.11° (50–59 years), 6.09° ± 9.95° (60–69 years), 6.57° ± 9.51° (70–79 years), and 5.53° ± 9.29° (≥ 80 years). The acetabular anteversion in women was 17.65° ± 6.58° (≤ 49 years), 19.24° ± 6.42° (50–59 years), 20.30° ± 6.25° (60–69 years), 22.38° ± 7.36° (70–79 years), and 23.34° ± 6.98° (≥ 80 years). The acetabular anteversion in men was 15.21° ± 8.14° (≤ 49 years), 17.68° ± 6.00° (50–59 years), 17.54° ± 5.93° (60–69 years), 18.68° ± 6.62° (70–79 years), and 18.19° ± 6.94° (≥ 80 years). The combined anteversion in women was 28.29° ± 14.30° (≤ 49 years), 34.99° ± 10.62° (50–59 years), 31.11° ± 11.52° (60–69 years), 34.76° ± 10.86° (70–79 years), and 34.57° ± 11.45° (≥ 80 years). The combined anteversion in men was 27.23° ± 15.11° (≤ 49 years), 28.30° ± 11.23° (50–59 years), 23.63° ± 11.77° (60–69 years), 25.25° ± 12.02° (70–79 years), and 23.72° ± 11.88° (≥ 80 years). Conclusions: Femoral anteversion tended to decrease with age in men and acetabular anteversion tended to increase in both men and women. Combined anteversion showed a tendency to increase slightly in women.

      • KCI등재

        Comparative Study for Osteosynthesis of Femoral Neck Fractures: Cannulated Screws versus Femoral Neck System

        Youngho Cho,Jaeuk Shin,Sangwoo Kim 대한고관절학회 2023 Hip and Pelvis Vol.35 No.1

        Purpose: The purpose of this study is to compare the radiological results of fixation using the femoral neck system (FNS) and cannulated screw (CS) for treatment of femoral neck fractures. Materials and Methods: A retrospective study of patients with femoral neck fractures who underwent internal fixation and had follow-up of more than six months from 2010 to 2020 was conducted. A total of 87 patients were enrolled in the study. The FNS group included 20 patients and the CS group included 67 patients. Classification of fractures was performed according to Garden and Pauwels classification. Operation time, intraoperative blood loss, sliding distance of the implant, lateral soft tissue irritation caused by implants, and complications were evaluated. Results: The mean operation time was 40.30 minutes in the FNS group and 46.84 minutes in the CS group. The mean intraoperative bleeding volume was 51.25 mL in the FNS group and 72.16 mL in the CS group. Bone union was achieved in 18 patients in the FNS group (90.0%) and in 61 patients in the CS group (91.0%). The mean sliding distance of the implant was 4.06 mm in the FNS group and 3.92 mm in the CS group. No patients in the FNS group and 12 patients in the CS group complained of soft tissue irritation. Conclusion: A shorter operative time, less intraoperative bleeding, and less irritation of soft tissue were observed in the FNS group. FNS could be an alternative to CS for fixation of femoral neck fractures.

      • KCI등재

        Osteoperiosteal Decortication and Autogenous Cancellous Bone Graft Combined with Bridge Plating for Non-hypertrophic Diaphyseal Nonunion

        Youngho Cho,Young-Soo Byun,Jeong-Duk Suh,Junhyug Yoo 대한정형외과학회 2021 Clinics in Orthopedic Surgery Vol.13 No.3

        Background: The aim of this study was to evaluate results of osteoperiosteal decortication and autogenous cancellous bone graft combined with a bridge plating technique in atrophic and oligotrophic femoral and tibial diaphyseal nonunion. Methods: We retrospectively reviewed 31 patients with atrophic or oligotrophic femoral and tibial diaphyseal nonunion treated with osteoperiosteal decortication and autogenous cancellous bone graft between January 2008 and December 2018. Patients with hypertrophic nonunion, infected nonunion, and nonunion treated with autogenous cancellous bone graft alone were excluded. The nonunion site was exposed by using the Judet technique of osteoperiosteal decortication. Nonunion with a lack of stability was stabilized with a new plate using a bridge plating technique or augmented by supplemental fixation with a plate. Nonunion with malalignment was stabilized with a new plate after deformity correction. Autogenous cancellous bone graft was harvested from the posterior iliac crest and placed within the area of decortication. A basic demographic survey was conducted, and the type of existing implants, mechanical stability of the implants, the type of implants used for stabilization, the operation time, the time to bone union, and postoperative complications were investigated. Results: The average follow-up period was 33.3 months (range, 8–108 months). The operation time was 207 minutes (range, 100– 351 minutes). All but 1 nonunion (96.7%) were healed at an average of 4.2 months (range, 3–8 months). In 1 patient, bone union failed due to implant loosening with absorbed bone graft, and solid union was achieved by an additional surgery for stable fixation with a new plate, osteoperiosteal decortication, and autogenous cancellous bone graft. There were no other major complications such as neurovascular injuries, infection, loss of fixation, and malunion. Conclusions: Osteoperiosteal decortication and autogenous cancellous bone graft combined with stable fixation by bridge plating showed reliable outcomes in atrophic and oligotrophic diaphyseal nonunion. This treatment modality can be effective for treating atrophic and oligotrophic diaphyseal nonunion because it is very helpful stimulating bone union.

      • KCI등재

        Plate Fixation for Atypical Fractures of the Femoral Diaphysis

        Youngho Cho,Young-Soo Byun,Seongwoo Jo,Jaeuk Shin 대한정형외과학회 2022 Clinics in Orthopedic Surgery Vol.14 No.2

        Background: Plate fixation for atypical femoral fractures has shown high failure rates compared to intramedullary nail fixation. The aim of this study was to evaluate the radiological results of patients treated with a plate and screws for atypical fractures of the femoral diaphysis. Methods: This study was conducted retrospectively on 16 patients who had undergone internal fixation using plates for treatment of atypical femoral complete fractures from 2007 to 2015. Nine patients were treated with lag screws and short plates while 7 patients were treated with position screws and long plates, which covered the whole femur. Radiologic evaluation was performed on all patients. Complications were also evaluated. Results: Bone union was achieved in all patients and the average bone union time was 17.7 weeks (range, 14–28 weeks). There was no correlation between the preoperative use of a bisphosphonate, plate length, postoperative teriparatide use, and the time to bone union. Regarding complications, 2 cases of complete fractures and 1 impending fracture occurred at the end of short plates. Conclusions: Satisfactory results were obtained with use of plates for patients with atypical femoral complete diaphyseal fractures, in whom intramedullary nails could not be applied due to severe bowing. In particular, it seemed advantageous compared with intramedullary nail fixation in that it could maintain the leg length through anatomical reduction and prevent iatrogenic fracture.

      • SCISCIESCOPUS

        Hyperspectral depth-profiling with deep Raman spectroscopy for detecting chemicals in building materials

        Cho, Youngho,Song, Si Won,Sung, Jiha,Jeong, Young-Su,Park, Chan Ryang,Kim, Hyung Min Royal Society of Chemistry 2017 The Analyst Vol.142 No.19

        <P>Toxic chemicals inside building materials have long-term harmful effects on human bodies. To prevent secondary damage caused by the evaporation of latent chemicals, it is necessary to detect the chemicals inside building materials at an early stage. Deep Raman spectroscopy is a potential candidate for on-site detection because it can provide molecular information about subsurface components. However, it is very difficult to spectrally distinguish the Raman signal of the internal chemicals from the background signal of the surrounding materials and to acquire the geometric information of chemicals. In this study, we developed hyperspectral wide-depth spatially offset Raman spectroscopy coupled with a data processing algorithm to identify toxic chemicals, such as chemical warfare agent (CWA) simulants in building materials. Furthermore, the spatial distribution of the chemicals and the thickness of the building material were also measured from one-dimensional (1D) spectral variation.</P>

      • KCI등재

        Changes in Biston robustum and Camellia japonica distributions, according to climate change predictions in South Korea

        Youngho Cho,Tae Guen Kim,한용구,Youngjin Kim,Ohseok KWON 한국생태학회 2015 Journal of Ecology and Environment Vol.38 No.3

        We investigated the current and potential spatial distributions and habitable areas of Biston robustum and Camellia japonica in South Korea in order to provide useful data for the conservation of C. japonica and minimize the damage caused by B. robustum. It was predicted that, by 2070, although B. robustum would be widely distributed throughout the Korean Peninsula, except for the western and eastern coastal areas, it would be narrowly distributed along the Sokcho-si and Goseong-gun coastlines in Gangwon Province. C. japonica is currently located along the southern coastline but its critical habitable area is predicted to gradually disappear by 2070. Assessment of the potential distribution probabilities of B. robustum and C. japonica revealed that the area under the curve (AUC) values were 0.995 and 0.991, respectively, which indicate high precision and applicability of the model. Major factors influencing the potential distribution of B. robustum included precipitation of wettest quarter and annual precipitation (BIO16 and BIO12), whereas annual mean temperature and mean temperature of wettest quarter (BIO1 and BIO8) were important variables for explaining C. japonica distribution. Overlapping areas of B. robustum and C. japonica were 11,782 km2, 5447 km2, and 870 km2 for the current, 2050-predicted, and 2070-predicted conditions, respectively, clearly showing a dramatic decrease in area. Although it is predicted that B. robustum would cause continuous damage to C. japonica in the southern part of the Korean Peninsula, such impacts might diminish over time and become negligible in the future.

      • Genetic Relationships between Mt. Halla and Mongolian Populations of Hipparchia autonoe (Lepidoptera: Nymphalidae)

        Youngho Cho,Jeong Sun Park,Min Jee Kim,Deuk-Soo Choi,Sang-Ho Nam,Iksoo Kim 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.04

        Hipparchia autonoe belongs to the family Nymphalidae (Lepidoptera) and is designated as an endangered insect and national monument in Korea. It only inhabits a very restricted area on Mt. Halla but is widely distributed in several Asian countries including Mongolia. A previous study conducted to understand the genetic relationship between Mt. Halla and Mongolian H. autonoe for conservation purposes suffered from a limited number of samples. Therefore, we sequenced the DNA barcode region of an additional 36 H. autonoe individuals, combined them with previous data from 19 individuals, and performed phylogenetic and population genetic analyses. Furthermore, the internal transcribed spacer 2 (ITS2) region was also sequenced from the 36 samples as a nuclear DNA marker. The existence of independent haplotypes, sequence types, and significant FST estimates (p < 0.05) between Mt. Halla and Mongolian populations indicated hampered gene flow between the populations. Nevertheless, an absence of a reciprocal monophyletic group in Mt. Halla and Mongolian populations by cytochrome oxidase subunit I gene- and ITS2-based phylogeny suggests that the genetic isolation of the Mt. Halla population from the Mongolian populations seemed not large enough to consider them independent genetic entities.

      • Phenotypic Characterization of Peripheral T Cells and Their Dynamics in Scrub Typhus Patients

        Cho, Bon-A,Ko, Youngho,Kim, Yeon-Sook,Kim, Sanguk,Choi, Myung-Sik,Kim, Ik-Sang,Kim, Hang-Rae,Cho, Nam-Hyuk Public Library of Science 2012 PLoS neglected tropical diseases Vol.6 No.8

        <▼1><P><B>Background</B></P><P>Scrub typhus, caused by <I>Orientia tsutsugamushi</I> infection, is one of the main causes of febrile illness in the Asia-Pacific region. Although cell-mediated immunity plays an important role in protection, little is known about the phenotypic changes and dynamics of leukocytes in scrub typhus patients.</P><P><B>Methodology/Principal Findings</B></P><P>To reveal the underlying mechanisms of immunological pathogenesis, we extensively analyzed peripheral blood leukocytes, especially T cells, during acute and convalescent phases of infection in human patients and compared with healthy volunteers. We observed neutrophilia and CD4<SUP>+</SUP> T lymphopenia in the acute phase of infection, followed by proliferation of CD8<SUP>+</SUP> T cells during the convalescent phase. Massive T cell apoptosis was detected in the acute phase and preferential increase of CD8<SUP>+</SUP> T cells with activated phenotypes was observed in both acute and convalescent phases, which might be associated or correlated with elevated serum IL-7 and IL-15. Interestingly, peripheral Treg cells were significantly down-regulated throughout the disease course.</P><P><B>Conclusions/Significance</B></P><P>The remarkable decrease of CD4<SUP>+</SUP> T cells, including Treg cells, during the acute phase of infection may contribute to the loss of immunological memory that are often observed in vaccine studies and recurrent human infection.</P></▼1><▼2><P><B>Author Summary</B></P><P>Scrub typhus is an acute febrile illness caused by <I>Orientia tsutsugamushi</I> infection. It has been estimated that one billion people are at risk and one million new cases arise each year in Asian-pacific region. Despite of aggressive attempts to develop a prophylactic vaccine against scrub typhus during the last several decades, all approaches have failed to generate long lasting immunity. In addition, little is known about the immunological pathogenesis of scrub typhus. To understand the pathogenic mechanisms of this infectious disease, we extensively analyzed peripheral leukocytes, especially T cells, in Korean scrub typhus patients and compared with healthy volunteers. We observed neutrophilia and CD4<SUP>+</SUP>/T lymphopenia in the acute phase of infection, followed by proliferation of CD8<SUP>+</SUP> T cells during the convalescent phase. Massive T cell apoptosis was detected in the acute phase and a preferential increase of CD8<SUP>+</SUP> T cells with activated phenotypes was observed in both acute and convalescent phases. The remarkable decrease of CD4<SUP>+</SUP> T cells, including Treg cells, during the acute phase of infection may contribute to the loss of immunological memory and generate helpless but unregulated cytotoxic T cell responses observed in vaccine studies and recurrent human infection.</P></▼2>

      • KCI등재

        LoRa Network based Parking Dispatching System

        Youngho Cho(조영호),Yeong Geon Seo(서영건),Dae-Yul Jeong(정대율) 한국디지털콘텐츠학회 2017 한국디지털콘텐츠학회논문지 Vol.18 No.7

        The purpose of this study is to develop an intelligent parking dispatching system based on LoRa network technology. During the local festival, many tourists come into the festival site simultaneously after sunset. To handle the traffic jam and parking dispatching, many traffic management staffs are engaged in the main road to guide the cars to available parking lots. Nevertheless, the traffic problems are more serious at the peak time of festival. Such parking dispatching problems are complex and real-time traffic information dependent. We used Queuing theory to predict inbound traffics and to measure parking service performance. Q-learning algorithm is used to find fastest routes and dispatch the vehicles efficiently to the available parking lots.

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