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A New Multiobjective Genetic Algorithm for Route Selection
Wen, Feng,Gen, Mitsuo,Yu, Xinjie The Institute of Electrical Engineers of Japan 2011 電氣學會論文誌. IEEJ Transactions on Electronics, Informa Vol.131 No.3
<P>In the area of Intelligent Transport Systems, the multiobjective route selection problem (mRSP) becomes an important key problem that needs to be solved in car navigation system (CNS). In this paper, we propose an effective route selection approach for solving mRSP while minimizing driving distance, driving time and driving cost simultaneously. A new multiobjective genetic algorithm (moGA) called distance Pareto Genetic Algorithm (dpGA) is presented to effectively solve mRSP. The mechanism of the proposed dpGA guarantees good convergence toward the Pareto-optimal front and gives sufficient emphasis on the diversity feature. The fitness function used in dpGA is based on two kinds of distance values, <I>i.e.</I> Pareto distance and crowding distance. Finally, we demonstrate the applicability and evaluate the efficiency of the proposed solution approach by using numerical experiments with the real digital road map data. The experimental results show the effectiveness of the proposed solution approach.</P>
( Yang Liu ),( Yifeng Li ),( Xinjie Yu ),( Leilei Yu ),( Fengwei Tian ),( Jianxin Zhao ),( Hao Zhang ),( Qixiao Zhai ),( Wei Chen ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.1
Lactobacillus casei, one of the most widely used probiotics, has been reported to alleviate multiple diseases. However, the effects of this species on intestinal diseases are strain-specific. Here, we aimed to screen L. casei strains with inflammatory bowel disease (IBD)-alleviating effects based on in vitro physiological characteristics. Therefore, the physiological characteristics of 29 L. casei strains were determined, including gastrointestinal transit tolerance, oligosaccharide fermentation, HT-29 cell adhesion, generation time, exopolysaccharide production, acetic acid production, and conjugated linoleic acid synthesis. The effects of five candidate strains on mice with induced colitis were also evaluated. The results showed that among all tested L. casei strains, only Lactobacillus casei M2S01 effectively relieved colitis. This strain recovered body weight, restored disease activity index score, and promoted anti-inflammatory cytokine expression. Gut microbiota sequencing showed that L. casei M2S01 restored a healthy gut microbiome composition. The western blotting showed that the alleviating effects of L. casei M2S01 on IBD were related to the inhibition of the NF-κB pathway. A good gastrointestinal tolerance ability may be one of the prerequisites for the IBD-alleviating effects of L. casei. Our results verified the efficacy of L. casei in alleviating IBD and lay the foundation for the rapid screening of L. casei strain with IBD-alleviating effects.
Rice Gene OsDSR-1 Promotes Lateral Root Development in Arabidopsis Under High-Potassium Conditions
Xu Ming Yin,Pedro S. C. F. Rocha,Man Ling Wang,Yu Xin Zhu,Luo Ye Li,Shu Feng Song,Xinjie Xia 한국식물학회 2011 Journal of Plant Biology Vol.54 No.3
Rice gene Oryza sativa Drought Stress Response-1 (OsDSR-1) was one of the genes identified to be responsive to drought stress in the panicle of rice at booting and heading stages by both microarray and quantitative real-time PCR analyses. OsDSR-1 encodes a putative calcium-binding protein, and its overexpression in Arabidopsis rendered transgenic plants to produce much shorter lateral roots (LRs) than wild-type (WT) plants in the medium supplemented with abscisic acid (ABA), suggesting that OsDSR-1 may act as a positive regulator during the process of ABA inhibition of LR development. No significant difference was observed in the total LR length between WT and transgenic plants in the media with the increase of only osmotic stress caused by NaCl, LiCl, and mannitol, while transgenic Arabidopsis seedlings appeared to produce larger root systems with longer total LR lengths under highpotassium conditions than WT seedlings. Further analysis showed that external Ca^2+ was required for the production of larger root systems, indicating that the promotion by OsDSR-1 of the LR development of transgenic Arabidopsis seemed to occur in a Ca^2+ -dependent manner under high-potassium conditions. We propose that OsDSR-1 may function as a calcium sensor of the signal transduction pathway controlling the LR development under high-potassium conditions.
Novel driver circuit for switching performance improvements in SiC MOSFETs
Li, Xianyun,Lu, Yi,Ni, Xijun,Wang, Shuzheng,Zhang, Yu,Tang, Xinjie The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.6
Silicon carbide (SiC) metal-oxide-semiconductor field-effect transistors (MOSFETs) are expected to be an attractive replacement for Si MOSFETs in high power applications due to their high blocking voltage, high switching speed, and low switching losses. However, a high switching speed can lead to voltage and current overshoot as well as oscillation during the switching process, which results in additional losses and severe electromagnetic interference. It can also exceed the limit of the SiC MOSFET and cause irreversible damage to the device. Based on an analysis of the SiC MOSFET switching process voltage and current overshoot and oscillation generation mechanism, a voltage-injected active gate driver (AGD) was proposed. The proposed AGD can suppress the voltage and current overshoot and oscillation by injecting voltage into the gate of the SiC MOSFET during specific switching stages. Experimental results show that when compared with the conventional gate driver (CGD), the proposed AGD can suppress the voltage and current overshoot peaks by 16% and 12%, while reducing voltage and current oscillation times by 58% and 31%, respectively.