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      • Selection of Optimal Decomposition Layer for Thresholding Denoising Using Singular Spectrum Analysis and Wavelet Entropy

        Zhi Cui,Xian-pu Cui 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.4

        To optimize the number of decomposition layers in wavelet threshold denoising for ultrasonic signals, we propose a self-adaptive algorithm of determining the number of decomposition layers based on singular spectrum analysis and wavelet entropy. First the noise-containing signals are decomposed by discrete wavelet transform. The slope of the singular value spectrum for each layer is estimated. Then the wavelet entropy over the signal subinterval is calculated for each layer. Finally the optimal number of decomposition layer is determined by combining the entropy ratio of detail coefficients to original signal and the slope of the singular value spectrum. The performance of the algorithm is evaluated using signal-to-noise ratio (SNR) and the relative error of the peak value (REPV). Experiment shows that the algorithm can self-adaptively determine the optimal number of decomposition layers and filter out the noise contained in the ultrasonic signals. It not only increases the SNR, but also preserves valuable components of the original signal.

      • Sparsity Based Denoising of PET-CT Images

        Zhi Cui,Xian-Pu Cui 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.2

        In this paper, we propose an improved method for the removal of additive Gussian white noise from PET-CT images. Different from the traditional sparse representation based denoising methods, our method is composed of two distinctively steps such as the preliminary denoise and the detail compensation. By constructing a sparse representation model, denoising is formulated as an optimization problem that can be solved on an over-complete dictionary. The proposed method effectively trains this dictionary by using K-SVD algorithm with atom replace model. Then the preliminary denoised image is reconstructed through improved OMP algorithm with the fidelity factor of SSIM (Structural Similarity). The detail compensation image is obtained by using the difference between the noisy image and the preliminary de-noised image, and the improved OMP algorithm is employed again to get the denoised detail compensation image. Finally, the final denoised image is reconstructed by adding the denoised detail compensation image to the preliminary denoised image. Experiment results have shown that the proposed method is better than some other denoising methods in terms of PSNR and SSIM.

      • Variants on ESR1 and their Association with Prostate Cancer Risk: A Meta-analysis

        Ding, Xiang,Cui, Feng-Mei,Xu, Song-Tao,Pu, Jin-Xian,Huang, Yu-Hua,Zhang, Jiang-Lei,Wei, Xue-Dong,Hou, Jian-Quan,Yan, Chun-Yin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

        Background: Epidemiological studies evaluating the association of two variants rs9340799 and rs2234693 on estrogen receptor 1 (ESR1) with prostate risk have generated inconsistent results. Methods: A meta-analysis was here conducted to systematically evaluate the relationship of these two variants with prostate cancer susceptibility. Results: For rs9340799, heterozygosity of T/C carriers showed a significant increased prostate cancer risk with a pooled odds ratio (OR) of 1.34 (95% CI = 1.06-1.69) while homozygote C/C carriers showed an increased but not statistically significant association with prostate cancer risk (pooled OR = 1.29, 95% CI = 0.94-1.79). Compared to the homozygous TT carriers, the allele C carriers showed a 31% increased risk for prostate cancer (pooled OR = 1.31, 95% CI = 1.06-1.63). No significant association between the rs2234693 and prostate cancer risk was found with the pooled OR of 1.15 (95% CI = 0.97-1.39, T/C and C/C vs. T/T) under the dominant genetic model. Compared to the homozygote T/T carriers, the heterozygous T/C carriers did not show any significantly different risk of prostate cancer (pooled OR = 1.13, 95% CI = 0.94-1.36) and the homozygous C/C carriers also did not show a significant change for prostate cancer risk compared to the wide-type T/T carriers (pooled OR = 1.26, 95% CI = 0.98-1.62). Conclusion: These data suggested that variant rs9340799, but not rs2234693, on ESR1 confers an elevated risk of prostate cancer.

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