[PF-0018] Analysis of major components of unripe and ripe fruits of radiation mutant micro-tomato population and evaluation of their cytotoxicity in FaDu cells

Jisu Park(Jisu Park ),Trung Huy Ngo(Trung Huy Ngo ),Yeong Deuk Jo(Yeong Deuk Jo ),Chang Hyun Jin(Chang Hyun Jin ),Joo-Won Nam(Joo-Won Nam ),Ah-Reum Han(Ah-Reum Han ) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

벌점회귀를 통한 서울시 미세먼지 예측

원지수(Jisu Won),나종화(Jonghwa Na) 한국데이터정보과학회 2021 한국데이터정보과학회지 Vol.32 No.3

최근 국내 미세먼지 (PM10)의 급증은 일상생활과 국민건강에 큰 영향을 주고 있다. PM10에 대한 원인 규명과 예측 문제는 그 동안 많은 연구자에 의해 수행되어왔으나 뚜렷한 해결책을 제시하지 못하고 있다. 본 연구에서는 PM10의 예측을 위해 기상 및 환경 요인을 예측변수로 하는 다양한 벌점 회귀의 방법을 제시하였다. 특히, 본 연구에서는 기상 및 환경 관련 예측변수의 최대 15일 이전 시점까지의 정보를 활용하였다. 이전 시점의 예측변수들 간에는 다중공선성의 문제가 발생하게 되는데, 이에 대한 해결책으로 본 논문에서는 벌점회귀의 방법을 적용하였다. 벌점회귀로는 Lasso, Adaptive lasso, SCAD와 MCP가 적용되었으며, 분석에는 서울시의 미세먼지농도 자료가 사용되었다. The recent rapid increase in domestic fine dust(PM10) has a great impact on daily life and public health. The problem of determining the cause of and predicting about PM10 has been carried out by many researchers, but has not been able to present a clear solution. In this study, various methods of penalized regression using meteorological and environmental factors as predictors were proposed for the prediction of PM10. In particular, in this study, information of weather and environment-related predictors up to 15 days ago was used. The problem of multicollinearity arises between the predictors at the previous point in time. As a solution to this, in this paper, the method of penalized regression is applied. Lasso, adaptive lasso, SCAD and MCP were applied as the penalty regression, and data from Seoul city were used for analysis.

Prediction of non-exercise activity thermogenesis (NEAT) using multiple linear regression in healthy Korean adults: a preliminary study

( Won-sang Jung ),( Hun-young Park ),( Sung-woo Kim ),( Jisu Kim ),( Hyejung Hwang ),( Kiwon Lim ) 한국운동영양학회 2021 Physical Activity and Nutrition (Phys Act Nutr) Vol.25 No.1

[Purpose] This preliminary study aimed to develop a regression model to estimate the non-exercise activity thermogenesis (NEAT) of Korean adults using various easy-to-measure dependent variables. [Methods] NEAT was measured in 71 healthy adults (male n = 29; female n = 42). Statistical analysis was performed to develop a NEAT estimation regression model using the stepwise regression method. [Results] We confirmed that age^A, weight^B, heart rate (HR)_average^C, weight × HR_average^D, weight × HR_ sum^E, systolic blood pressure (SBP) × HR_rest^F, fat mass ÷ height^2G, gender × HR_average^H, and gender × weight × HR_sum^I were important variables in various NEAT activity regression models. There was no significant difference between the measured NEAT values obtained using a metabolic gas analyzer and the predicted NEAT. [Conclusion] This preliminary study developed a regression model to estimate the NEAT in healthy Korean adults. The regression model was as follows: sitting = 1.431 - 0.013 × (A) + 0.00014 × (D) - 0.00005 × (F) + 0.006 × (H); leg jiggling = 1.102 - 0.011 × (A) + 0.013 × (B) + 0.005 × (H); standing = 1.713 - 0.013 × (A) + 0.0000017 × (I); 4.5 km/h walking = 0.864 + 0.035 × (B) + 0.0000041 × (E); 6.0 km/h walking = 4.029 - 0.024 × (C) + 0.00071 × (D); climbing up 1 stair = 1.308 - 0.016 × (A) + 0.00035 × (D) - 0.000085 × (F) - 0.098 × (G); and climbing up 2 stairs = 1.442 - 0.023 × (A) - 0.000093 × (F) - 0.121 × (G) + 0.0000624 × (E).

Comparison of excess post-exercise oxygen consumption of different exercises in normal weight obesity women

( Won-sang Jung ),( Hyejung Hwang ),( Jisu Kim ),( Hun-young Park ),( Kiwon Lim ) 한국운동영양학회 2019 Physical Activity and Nutrition (Phys Act Nutr) Vol.23 No.2

[Purpose] The purpose of this study was to compare the excess post-exercise oxygen consumption (EPOC) between different types of exercises in women with normal weight obesity (NWO). [Methods] Nine university students with NWO having body mass index < 25 kg/m² and body fat percentage >30% participated in the study. First, continuous exercise (CEx) on an ergometer for 30 minutes at 60% of maximal oxygen consumption (VO_2max) and interval exercise (IEx) at 80% VO_2max for 2 minutes were performed. This was followed by exercise performed at 40% VO_2max for 1 minute and at 80% VO_2max for 3 minutes, performed 6 times repeatedly for a total of 26 minutes. The accumulation of short duration exercise (AEx) was performed for 3-bouts of 10 minutes each at 60% VO_2max. [Results] The major findings were as follows: energy consumption during the exercises showed no significant difference between CEx, IEx, and AEx; EPOC was higher in IEx and AEx as compared to CEx for all dependent variables (e.g. total oxygen consumption, total calorie, summation of heart rate, and EPOC duration); and the lipid profile showed no significant difference. [Conclusions] Our study confirmed that when homogenizing the energy expenditure for various exercises in NWO individuals, EPOC was higher in IEx and AEx than in CEx. Therefore, IEx and AEx can be considered as effective exercise methods for increasing energy expenditure in NWO females.

The effect of epidermal growth factor-containing cream on the postinflammatory hyperpigmentation after Laser treatment

( Jisu Han ),( Do Young Rhee ),( Gyeong Hoon Park ),( Chong Hyun Won ),( Sung Eun Chang ),( Mi Woo Lee ),( Jee Ho Choi ),( Kee Chan Moon ) 대한피부과학회 2012 대한피부과학회 학술발표대회집 Vol.64 No.3

Estimating excess post-exercise oxygen consumption using multiple linear regression in healthy Korean adults: a pilot study

( Won-sang Jung ),( Hun-young Park ),( Sung-woo Kim ),( Jisu Kim ),( Hyejung Hwang ),( Kiwon Lim ) 한국운동영양학회 2021 Physical Activity and Nutrition (Phys Act Nutr) Vol.25 No.1

[Purpose] This pilot study aimed to develop a regression model to estimate the excess post-exercise oxygen consumption (EPOC) of Korean adults using various easy-to-measure dependent variables. [Methods] The EPOC and dependent variables for its estimation (e.g., sex, age, height, weight, body mass index, fat-free mass [FFM], fat mass, % body fat, and heart rate_sum [HR_sum]) were measured in 75 healthy adults ( 31 males, 44 females). Statistical analysis was performed to develop an EPOC estimation regression model using the stepwise regression method. [Results] We confirmed that FFM and HR_sum were important variables in the EPOC regression models of various exercise types. The explanatory power and standard errors of estimates (SEE) for EPOC of each exercise type were as follows: the continuous exercise (CEx) regression model was 86.3% (R²) and 85.9% (adjusted R²), and the mean SEE was 11.73 kcal, interval exercise (IEx) regression model was 83.1% (R²) and 82.6% (adjusted R²), while the mean SEE was 13.68 kcal, and the accumulation of short-duration exercise (AEx) regression models was 91.3% (R²) and 91.0% (adjusted R²), while the mean SEE was 27.71 kcal. There was no significant difference between the measured EPOC using a metabolic gas analyzer and the predicted EPOC for each exercise type. [Conclusion] This pilot study developed a regression model to estimate EPOC in healthy Korean adults. The regression model was as follows: CEx = -37.128 + 1.003 × (FFM) + 0.016 × (HR_sum), IEx = -49.265 + 1.442 × (FFM) + 0.013 × (HR_sum), and AEx = -100.942 + 2.209 × (FFM) + 0.020 × (HR_sum).

Proteomic Reference Map and Comparative Analysis between Streptomyces griseus S4-7 and wbiE2 Transcription Factor-Mutant Strain

Jisu Kim,Young Sang Kwon,Dong-Won Bae,Youn-Sig Kwak 한국식물병리학회 2020 Plant Pathology Journal Vol.36 No.2

Streptomyces griseus S4-7, a well-characterized key- stone taxon among strawberry microbial communi- ties, shows exceptional disease-preventing ability. The whole-genome sequence, functional genes, and bioactive secondary metabolites of the strain have been described in previous studies. However, proteomics studies of not only the S4-7 strain, but also the Streptomyces genus as a whole, remain limited to date. Therefore, in the pres- ent study, we created a proteomics reference map for S. griseus S4-7. Additionally, analysis of differentially expressed proteins was performed against a wblE2 mu- tant, which was deficient in spore chain development and did not express an antifungal activity-regulatory transcription factor. We believe that our data provide a foundation for further in-depth studies of functional keystone taxa of the phytobiome and elucidation of the mechanisms underlying plant-microbe interactions, es- pecially those involving the Streptomyces genus.

The Effect of a Dedicated Intensivist Staffing on Emergency Airway Management by Rapid Response Team in General Ward

( Jisu Yu ),( Da-hye Kim ),( Eun-joo Choi ),( Sang-bum Hong ),( Jin-won Huh ),( Chae-man Lim ),( Younsuck Koh ),( Dong Kyu Oh ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.0

Background Although the rapid response system is widely spreading, many of them are operated without a dedicated staff. We investigated the changes in emergency airway management by rapid response team (RRT) after a dedicated intensivist staffing. Methods A single-center retrospective non-interventional study was performed at a tertiary hospital. Patients who required emergency airway management by RRT between January 2015 and December 2019 were included. We divided the study period into two eras, non-staff-led (from January 2015 to February 2018, n=971) and staff-led (from March 2018 to December 2019, n=651), and compared variables related to airway management. Results Among 1,622 patients, mean age was 63.0 years and male were 64.2% (n=1,042). Difficult airway was assessed in 306 (18.9%) patients. The first pass success rate was significantly higher (85.9% in the non-staff-led era vs. 89.2% in the staff-led era, p=0.047) and the post-intubation hypoxemia was less common (7.2% vs. 4.2%, p=0.018) in the staff-led era. The ROX index at the time of intubation was higher in the staff-led era (median [interquartile range]; 4.6 [3.4-7.6] vs. 5.1 [3.6-8.5], p=0.013), which suggests the decision for intubation was made earlier. In addition, the use of rapid sequence intubation (9.4% vs. 34.4%, p<0.001) and videolaryngoscope (88.2% vs. 97.1%, p<0.001) were also more frequent in the staff-led era. In multivariate analysis, factors associated with first pass success were the experience of clinician (odds ratio [95% confidence interval]; 2.375 [1.662-3.393], p<0.001 for intensive care unit fellows and 14.316 [1.908-107.415], p=0.010 for RRT staff, relative to internal medicine residents), the use of videolaryngoscope (5.462 [3.428-8.701], p<0.001) and rapid sequence intubation (3.325 [1.839- 6.012], p<0.001), and difficult airway (0.331 [0.224-0.489], p<0.001). Conclusions A dedicated intensivist staffing to RRT was associated with improved emergency airway management in general ward.

Effect of interval exercise versus continuous exercise on excess postexercise oxygen consumption during energy-homogenized exercise on a cycle ergometer

( Won-sang Jung ),( Hyejung Hwang ),( Jisu Kim ),( Hun-young Park ),( Kiwon Lim ) 한국운동영양학회 2019 Physical Activity and Nutrition (Phys Act Nutr) Vol.23 No.2

[Purpose] The purpose of this study was to confirm that the difference in excess post-exercise oxygen consumption (EPOC) during exercise of the spending the same calories between the continuous and interval exercise. [Methods] Thirty-four healthy college students who did not regularly exercise volunteered to participate in our study. Continuous exercise was performed on an ergometer for 30 min at 60% of maximal oxygen consumption (VO_{2 max}). Interval exercise was performed on a cycle ergometer at 80% VO_{2 max} for 2 min initially, followed by 40% VO_{2 max} for 1 min, and 80% VO_{2 max} for 3 min. This was repeated six times for a total of 26 min. [Results] The major findings were as follows: (1) energy consumption during exercise was not significantly different between continuous exercise and interval exercise groups; (2) EPOC was higher in interval exercise than in continuous exercise for all dependent variables (i.e., total oxygen consumption, total calories, summation of heart rate); and (3) there were no significant differences in the lipid profile between continuous and interval groups. [Conclusions] Our study confirmed that after equalizing energy expenditure for continuous and interval exercise on a cycle ergometer in subjects in their twenties, interval exercise results in higher EPOC than continuous exercise. These data suggest that interval exercise may be more effective than continuous exercise in reducing body fat, for a given amount of energy expenditure.

Impact of clay minerals on bacterial diversity during the fermentation process of kimchi

Kang, Jisu,Chung, Won-Hyong,Nam, Young-Do,Kim, Daeyoung,Seo, Sung Man,Lim, Seong-Il,Lee, So-Young Elsevier 2018 Applied clay science Vol.154 No.-

<P><B>Abstract</B></P> <P>Kimchi is a popular traditional Korean food and has various beneficial health properties, e.g., it has preventative effects against cancer, obesity, diabetes, and constipation. The characteristics of kimchi, including its texture, flavor, and functionality, are affected by the major and minor ingredients. Bentonite, a clay mineral, is used as a component in functional foods, cosmetics, and pharmaceuticals owing to its physical and chemical characteristics. In this study, different types of cation-substituted forms of bentonite (Na<SUP>+</SUP>, K<SUP>+</SUP> and Mg<SUP>2+</SUP>) were used as kimchi ingredients to analyze their effect on the microbial community during fermentation for 10days. Amplicon sequencing targeting the bacterial 16S rRNA gene was conducted using the ion torrent PGM system and sequencing data were analyzed with Qiime. At the initial stage, kimchi samples exhibited diverse microflora. Lactic acid bacteria (LAB), such as <I>Weissella, Lactobacillus</I>, and <I>Lactococcus</I>, dominated after 10days of fermentation. Seven core LAB species, i.e., <I>Leuconostoc gelidum</I>, <I>Leuconostoc gasicomitatum</I>, <I>Weissella koreensis</I>, <I>Leuconostoc citreum</I>, <I>Leuconostoc lactis</I>, <I>Lactobacillus sakei</I>, and <I>Weissella cibaria</I>, showed differences in abundance among samples treated with different types of bentonite.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The effects of bentonite, a clay mineral, on kimchi properties were examined. </LI> <LI> Kimchi was treated with 6 bentonite types modified with different cations. </LI> <LI> The kimchi microflora was dominated by LAB after a 10-day fermentation. </LI> <LI> Seven LAB species differed according to the cation-substituted form of bentonite. </LI> </UL> </P>