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- 저자 : Wang Wenhang (검색결과 2 건)
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Weijiang Fan,Wenhang Wang,Lan Zhang,Lihong Qi,Anjun Liu,Anjun Liu 대한독성 유전단백체 학회 2016 Molecular & cellular toxicology Vol.12 No.2
This study investigated the effects of treatment with trivalent chromium (Cr3+) on the cytokine levels in mice that had alloxan-induced hepatic injury. The results showed that chromium picolinate (CrPic) may have a protective effect against hepatic injury and that these effects might be related to changes in cytokine expression. Blood ALT and AST levels in the alloxan mice were higher than those in the control and CrPic-treated groups (no significant differences between the latter groups). Luminex assays of cytokines from Th1 (TNF-α, IL-2 and IL-9) and Th2 (IL-3, IL- 5, IL-6, IL-10, IL-13) - as well as G-CSF, M-CSF, and GM-CSF - demonstrated increased levels of TNF-α, IL-2, and IL-9 (55.10%, 1.05-fold, and 2.14-fold, respectively) in alloxan-treated mice compared to control mice. Further, compared to the control group, liver IL- 3, -5, -6, -10, and -13 levels were decreased 2.45-fold, 1.54-fold, 1.01-fold, 12.6% and 37.3%, respectively, in the alloxan-treated mice. In comparison to the control mice, the levels of G-CSF, M-CSF and GM-CSF were decreased in the alloxan-treated mice (25.2%, 49.5%, and 52.9%, respectively). These cytokines were increased 7.91-fold, 43.67% and 34.05%, respectively, in the CrPic-treated group. These findings suggest that Th1/Th2 type cytokines are involved in hepatic injury and induced by alloxan, which may provide a new possible therapeutic approach through CrPic-treatment.
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Ammonia etched petroleum pitch-based porous carbon as efficient catalysts for CO2 electroreduction
Ning Hui,Guo Zhihao,Wang Wenhang,Wang Xiaoshan,Yang Zhongxue,Ma Zhengguang,Tian Yangming,Wu Chenghao,Hao Jian,Wu Mingbo 한국탄소학회 2022 Carbon Letters Vol.32 No.3
Electrochemical reduction of carbon dioxide to valuable chemicals is a promising way of storing renewable energy through electric-to-chemical energy conversion, while its large-scale application is in urgent need of cheap and high-performance catalysts. Herein, we invent a convenient method to synthesize N-doped porous carbon by ammonia etching the pyrolysis carbon of petroleum pitch. We found the ammonia etching treatment not only increase the pyridinic-N content, but also enlarge the specific surface area of the petroleum pitch-based porous carbon. As a cheap and easily available catalyst for carbon dioxide electroreduction, up to 82% of Faradaic efficiency towards carbon monoxide was obtained at − 0.9 V vs the reversible hydrogen electrode in 0.1 M KHCO3. After a long time electrocatalysis of more than 20 h, the Faradaic efficiency of carbon monoxide remains 80%, indicating the porous carbon as made have an ultra-high stability as catalyst for carbon dioxide reduction. Our work provides a new technology to economically prepare efficient electrocatalysts for carbon dioxide reduction.
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