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- 저자 : Wan-Hsuan Lin (검색결과 2 건)
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Wan-Hsin Chang,Pei-Yi Liu,Chien-Ju Lu,Dai-En Lin,Min-Hsuan Lin,Yuan-Ting Jiang,Yuan-Hao Howard Hsu 한국고분자학회 2020 Macromolecular Research Vol.28 No.12
Biocompatible 2-methacryloyloxyethyl phosphorylcholine (MPC) can enhance the adsorption of water molecules and is therefore used for manufacturing contact lenses. This study investigated the mechanical strength, anti-protein deposition, and anti-lipid adsorption effects of MPC addition to contact lenses. Experimental contact lenses produced by copolymerizing multiple ratios of MPC to 2-hydroxyethyl methacrylate (HEMA) were analyzed. Atomic force microscopy revealed that MPC addition increased surface roughness. The anti-protein deposition and anti-lipid adsorption effects on poly(HEMA-MPC) polymers of various phosphorylcholine quantities were experimentally confirmed. The water content of the contact lenses was proportional to the MPC content in the polymer. The hydrated PC moiety of MPC drastically altered the network of the poly-HEMA polymer by inserting water molecules, which were trapped in the concave region of the surface. MPC addition had negative effects on all examined strength factors because of structural destabilization of the copolymer through water insertion. The anti-deposition effects of MPC were verified by examining the lysozyme and lipid adsorption abilities of the prepared contact lenses. Our results revealed that MPC enhanced interactions of the poly(HEMA-MPC) copolymer with water molecules; these interactions weakened the mechanical strength of the copolymer but markedly improved the anti-adsorption property of the biomolecules. The optimal proportion of HEMA–MPC for contact lenses is in the range 14.9%-28.5%.
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Yi-Kai Juan,Wan-Hsuan Lin 서울시립대학교 도시과학연구원 2023 도시과학국제저널 Vol.27 No.1
Although the overall crime rate in Taiwan has shown a declining trend in recent years, the proportion of burglaries remains high. Most studies regarding the prevention of burglaries proceed from the perspectives of population composition or criminal psychology, and place focus on the internal spatial planning of buildings without mentioning the association between case locations and urban environments. In order to effectively prevent crime and improve the quality of life, this study utilized cases provided by the Taipei City Government Open Platform (Data. Taipei) to confirm the surrounding environmental factors and building data of burglary cases for data mining application. The proposed method consists of two phases: clustering and association rule mining. In the clustering phase, the key substructures of environmental information are collected; then characteristics in each cluster are analyzed based on the association rule. The results of analysis showed that the first group (Group 1) in the classification should give priority to improving the visibility of idle space and streets, while the second group (Group 2) should improve the efficiency of personnel surveillance and solve the problem of crowds caused by business activities. The third group (Group 3), which featured narrow lanes and insufficient street lamps on chaotic streets, should engage in overall planning and design. Some studies have found that the environmental characteristics of burglary cases in Taipei City are different from the characteristics of crime-saddled urban areas defined by international scholars. Such differences deserve further study. The findings of this study can serve as an environmental design model for future urban development.
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