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Aging of Skeletal Muscle Fibers
Natasa Miljkovic,임재영,Iva Miljkovic,Walter R. Frontera 대한재활의학회 2015 Annals of Rehabilitation Medicine Vol.39 No.2
Aging has become an important topic for scientific research because life expectancy and the number of men and women in older age groups have increased dramatically in the last century. This is true in most countries of the world including the Republic of Korea and the United States. From a rehabilitation perspective, the most important associated issue is a progressive decline in functional capacity and independence. Sarcopenia is partly responsible for this decline. Many changes underlying the loss of muscle mass and force-generating capacity of skeletal muscle can be understood at the cellular and molecular levels. Muscle size and architecture are both altered with advanced adult age. Further, changes in myofibers include impairments in several physiological domains including muscle fiber activation, excitation-contraction coupling, actin-myosin cross-bridge interaction, energy production, and repair and regeneration. A thorough understanding of these alterations can lead to the design of improved preventative and rehabilitative interventions, such as personalized exercise training programs.
Bounce Forward Better: Geriatric and Gerontological Research in the Post-pandemic Future
Jee Hyun Noh,Hidenori Arai,Tung Wai Auyeung,Matteo Cesari,Walter R. Frontera,Hyuk Ga,Hee-Won Jung,Wee Shiong Lim,Jae Young Lim 대한노인병학회 2022 Annals of geriatric medicine and research Vol.26 No.4
In recent years, we have faced challenges in managing coronavirus disease 2019 (COVID-19), especially in older adults. The pandemic has precipitated a global health crisis that impeded older adults from maintaining their health. Disruption of the routine management of chronic diseases, physical inactivity deteriorating physical function and quality of life, malnutrition, and mental disorders have been suggested as major threats to the health of older adults. To address these problems and facilitate reactivation of normal care activities, this article summarizes the contents of a webinar held by the Annals of Geriatric Medicine and Research (AGMR) regarding the future directions of geriatric medicine and research in the post-COVID-19 era.