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Zhang, Mingzi,Ahn, Woosung,Kim, Sumin,Hong, Hyun Sook,Quan, Chengshi,Son, Youngsook John Wiley & Sons Ltd. 2017 Microcirculation Vol.24 No.8
<P><B>Abstract</B></P><P><B>Objective</B></P><P>The aim of this study was to evaluate the angiogenicity of a combination of BM‐EPCs and BM‐MSCs in vitro in the presence of SP and its working mechanism.</P><P><B>Methods</B></P><P>BM‐MSCs and BM‐EPCs were cocultured with or without SP. ELISA and RT‐PCR were performed to detect angiogenic factors such as VEGF and PDGF‐BB. N‐cadherin was detected by Western blot analysis. The tubular network‐forming ability was evaluated by a Matrigel tube‐forming assay.</P><P><B>Results</B></P><P>BM‐EPCs coculture with BM‐MSCs strongly stimulated the recruitment of BM‐MSCs onto the BM‐EPC‐generated endothelial tubular network. Upon SP treatment, endothelial branching point, tubule length, and tubular recruitment of BM‐MSCs were further increased and stabilized. The coculture of BM‐EPCs and BM‐MSCs synergistically stimulated expression of VEGF, VEGF receptor, N‐cadherin, and PDGF‐BB, all of which were further enhanced by SP treatment. Blockade of PDGF‐BB by its functional blocking antibodies markedly reduced the BM‐MSC incorporation into the endothelial tubules. SP‐pretreated BM‐MSCs were preferentially incorporated into the preformed BM‐EPC tubular network.</P><P><B>Conclusions</B></P><P>BM‐EPCs along with SP promote the pericyte‐like coverage of BM‐MSCs on endothelial tubules possibly through the induction of PDGF‐BB.</P>
Wenjun Zhang,Yi Chen,Yanlin Li,Sumin Guan,Yan Chen,Qian-Qian Yang,Lu Liu,Qing-Chen Xue,Yu-Cui Guang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.10
"In this work, organic–inorganic hybrid ultrathin transparent films (UTFs), produced by layer-by-layer (LBL) assembly of the europium inclusion complex of β-cyclodextrin ( β-CD) and Mg–Al layered double hydroxide (MgAl–NO3–LDHs) nanosheets, are reported. UV-visible (UV-Vis) absorption and fluorescence spectroscopy show orderly growth of the europium inclusion complex of β-CD/layered double hydroxide (EICC/LDH) films with an increasing number of deposition cycles. X-ray diffraction and scanning electron microscopy measurements indicate that the films feature periodic layered structures with uniform surface morphology. Moreover, when EICC is assembled with inorganic rigid LDH nanosheets, the lifetimes are prolonged due to the isolation effect, and the UTFs are transparent with high brightness, which indicate that these films could serve as new optical materials."
RESEARCH ON MILLIMETER WAVE RADAR SIMULATION MODEL FOR INTELLIGENT VEHICLE
Xin Li,Weiwen Deng,Sumin Zhang,Yaxin Li,Shiping Song,Shanshan Wang,Guanyu Wang 한국자동차공학회 2020 International journal of automotive technology Vol.21 No.2
Radar simulation models can effectively overcome the drawbacks of real vehicle experiment and speed up the development process of intelligent vehicle technologies based on millimeter wave radar via virtual testing. However, there are still many gaps between the radar model using in the virtual driving environment and the real radar. In this paper, a novel simulation model of intelligent vehicle millimeter wave radar is proposed. Based on the analysis of the real radar performance in typical application scenes, the radar model considers the mechanism and characteristics of the vehicle radar synthetically and a systematic radar modeling architecture with innovation is introduced. The highlights of this radar model include the design of the RCS simulation model for radar targets with both high accuracy and real-time performance, the establishment of the quantitative false alarm model, missed detection model and measurement error simulation model. Vast amounts of data collected by real vehicle radar are applied to fetch model parameters and verify the accuracy of the radar model. Simulation results show that the proposed model can reach both high reliability and computational efficiency.