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      • Effect of acceptor doping on phase transitions of HfO<sub>2</sub> thin films for energy-related applications

        Park, Min Hyuk,Schenk, Tony,Hoffmann, Michael,Knebel, Steve,,rtner, Jan,Mikolajick, Thomas,Schroeder, Uwe Elsevier 2017 Nano energy Vol.36 No.-

        <P><B>Abstract</B></P> <P>Fluorite structured HfO<SUB>2</SUB> or ZrO<SUB>2</SUB> thin films have been intensively studied for memory- and energy-related applications since their ferroelectricity was first reported in 2011. The phase transition between the nonpolar tetragonal and the polar orthorhombic phase in these new ferroelectric materials is believed to be promising for energy harvesting, energy storage and solid state cooling. The temperature dependent phase transition and resulting strong pyroelectric and electrocaloric effect have been reported for Si-doped HfO<SUB>2</SUB> and (Hf,Zr)O<SUB>2</SUB> thin films. In this study, the effect of acceptor (Al and Gd) doping into HfO<SUB>2</SUB> thin films on their temperature dependent phase transition was systematically examined. The phase transitions in Al- and Gd-doped HfO<SUB>2</SUB> thin films were much broader compared to Si-doped HfO<SUB>2</SUB> and (Hf,Zr)O<SUB>2</SUB> films. The maximum adiabatic temperature change (ΔT) values of Al- and Gd-doped HfO<SUB>2</SUB> film were 5.7 and 3.1K, respectively. A giant negative electrocaloric effect with ΔT of −7.4K could be observed for Al-doped HfO<SUB>2</SUB>. The various factors which can potentially affect the phase transitions of HfO<SUB>2</SUB> films, such as dopant size, grain size distribution, spatial dopant distribution, and oxygen vacancy distribution were carefully examined to understand the different phase transition behavior. From the various factors, the distribution of oxygen vacancies is suggested as the origin of the different phase transitions of HfO<SUB>2</SUB> films doped with trivalent and tetravalent dopants.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Phase transition of Al- and Gd-doped HfO<SUB>2</SUB> films are reported for the first time. </LI> <LI> The effect of acceptor doping on the phase transition of fluorite ferroelectrics is investigated in depth. </LI> <LI> The energy harvesting and storage as well as electrocaloric effect of Al- and Gd-doped HfO<SUB>2</SUB> thin films is examined and compared to other materials. </LI> </UL> </P> <P><B>Graphic abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Whither systems medicine?

        Rolf Apweiler,Tim Beissbarth,Michael R Berthold,Nils Blüthge,Yvonne Burmeister,Olaf Dammann,Andreas Deutsch,Friedrich Feuerhake,Andre Franke,Jan Hasenauer,Steve Hoffmann,Thomas Höfer,Peter LM Jansen,L 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

        New technologies to generate, store and retrieve medical and research data are inducing a rapid change in clinical and translational research and health care. Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from biology, biostatistics, informatics, mathematics and computational modeling to develop methods to use new and stored data to the benefit of the patient. We here provide a critical assessment of the opportunities and challenges arising out of systems approaches in medicine and from this provide a definition of what systems medicine entails. Based on our analysis of current developments in medicine and healthcare and associated research needs, we emphasize the role of systems medicine as a multilevel and multidisciplinary methodological framework for informed data acquisition and interdisciplinary data analysis to extract previously inaccessible knowledge for the benefit of patients.

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