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RISS 인기검색어
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- 저자 : Shohei Mikami (검색결과 3 건)
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( Shohei Sumi ),( Norihisa Ishimura ),( Hironobu Mikami ),( Eiko Okimoto ),( Yuji Tamagawa ),( Tsuyoshi Mishiro ),( Yoshikazu Kinoshita ),( Shunji Ishihara ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2021 Journal of Neurogastroenterology and Motility (JNM Vol.27 No.3
Background/Aims The gastric acid pocket has an important role in gastroesophageal reflux disease development. In this study, we utilized a novel 8-channel pH monitoring system with sensor intervals of 1 cm on the vertical axis for evaluation of postprandial gastric acid pocket in healthy Japanese adults, as well as the effects of vonoprazan and rabeprazole. Methods Twelve healthy volunteers without Helicobacter pylori infection were enrolled. A catheter was inserted transnasally and positioned under X-ray guidance, then postprandial acid pocket formation was monitored over time in a sitting position. Thereafter, acid pocket changes were assessed following administration of vonoprazan (20 mg) or rabeprazole (20 mg). Results The gastric acid pocket was successfully measured by use of the present system in 10 cases, while failure occurred in 2 because of inappropriate catheter positioning. Observed acid pockets were visualized with a mean length of 2.2 ± 0.4 channels on the top layer of food contents approximately 20 minutes after finishing a meal. There were some variations for lasting time of the acid pocket. Complete elimination within 3 hours after administration of vonoprazan was noted in all cases. Likewise, following administration of rabeprazole, the acid pocket was eliminated in 7 cases, while acidity was reduced though the pocket remained observable in 3. Conclusions Gastric acid pocket observations were possible using our novel vertical 8-channel sensor catheter. The present findings showed that vonoprazan strongly suppressed acid secretion within a short period, suggesting its effectiveness for gastroesophageal reflux disease treatment. (J Neurogastroenterol Motil 2021;27:370-376)
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Taku Tsujimura,Kaoru Nakatani,Shohei Mikami,Yoshiroh Tokunaga,Jiro Senda,Hajime Fujimoto 한국자동차공학회 2001 한국자동차공학회 Symposium Vol.- No.-
We focused on the hydrogen fueled, direct-injection diesel engine in an inen gas circulation type co-generation system which had been proposed by WE-NET project. In this study, chemical kinetic analysis with a detailed chemi-cal kinetic model for hydrogen was conducted to understand the characteristic of auto-ignition phenomena with investigating the effects of temperature, pressure, fuel concentration, and third body concentration in hydrogen mixture on auto-ignition delay time. It was found that temperature of mixture had a strong effect on auto-ignition delay especially at less than 1100 K. It is found that richer mixture ignites earlier, and that the increase in third body concentration causes the increase in auto-ignition delay time because third body dilutes chemical species related with auto-ignition. Moreover as supposed that mixture is formed in a cylinder by means of direct-injection method, it is clarified that third body concentration and temperature in the mixture vary with the change in equivalence ratio of the mixture, and it can be supposed that leaner mixture spontaneously ignites earlier because temperature of lean mixture is higher than one of rich mixture.<br/> <br/>
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Funayama, Akinori,Kojima, Taku,Yoshizawa, Michiko,Mikami, Toshihiko,Kanemaru, Shohei,Niimi, Kanae,Oda, Yohei,Kato, Yusuke,Kobayashi, Tadaharu Korean Association of Maxillofacial Plastic and Re 2017 Maxillofacial Plastic Reconstructive Surgery Vol.39 No.-
Background: Mandibular reconstruction is performed after segmental mandibulectomy, and precise repositioning of the condylar head in the temporomandibular fossa is essential for maintaining preoperative occlusion. Methods: In cases without involvement of soft tissue around the mandibular bone, the autopolymer resin in a soft state is pressed against the lower border of the mandible and buccal and lingual sides of the 3D model on the excised side. After hardening, it is shaved with a carbide bar to make the proximal and distal parts parallel to the resected surface in order to determine the direction of mandibular resection. On the other hand, in cases that require resection of soft tissue around the mandible such as cases of a malignant tumor, right and left mandibular rami of the 3D model are connected with the autopolymer resin to keep the preoperative position between proximal and distal segments before surgical simulation. The device is made to fit the lower border of the anterior mandible and the posterior border of the mandibular ramus. The device has a U-shaped handle so that adaptation of the device will not interfere with the soft tissue to be removed and has holes to be fixed on the mandible with screws. Results: We successfully performed the planned accurate segmental mandibulectomy and the precise repositioning of the condylar head by the device. Conclusions: The present technique and device that we developed proved to be simple and useful for restoring the preoperative condylar head positioning in the temporomandibular fossa and the precise resection of the mandible.
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