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      • KCI등재

        두경부 암환자의 방사선요법시 구강내 캔디다속에 대한 연구

        Shin Jung Cha(車信正),Eui Wung Lee(李義雄),Jung Ho Yoon(尹仲鎬) 대한구강악안면외과학회 1980 대한구강악안면외과학회지 Vol.6 No.1

        80 cases of head and neck cancer were subjected to oral culture for Candida species during radiotherapy in Yonsei Cancer Institute and Korea atomic Hospital. And 40 cases of healthy People were cultured as a control group. Irradiation was carried out using Co 60 TeleTherapy Units in all patients. Classification of Candida Genus was done using API 20 Candide Kits. The results were as follows, 1. Control group was revealed with 22.5 % positive culture of Candida. 2. Positive culture of Candida species on patients irradiated under 3000R was 30.8%. 3. Positive culture of Candida species on patients irradiated over 3000R was 50.0%. 4. 35 Candida species of eighty irradiated patients were consisted of 28 of C.albicans, 4 of C. tropicalis, each 1 of C.krusei, C. zeylanoids, and undetermined Candide sp. 5. Nine Candida species of forty control group were consisted of 5 of Candida albicans, 2 of C. guilliermondii, each 1 of C. zeylanoids and C. parapsilisis.

      • KCI등재

        ALLOXAN유도 당뇨백서의 혈청과 과립구가 CANDIDA ALBICANS에 미치는 영향에 관한 연구

        신정(Shin Jung Cha) 대한구강악안면외과학회 1984 대한구강악안면외과학회지 Vol.10 No.1

        In the present study, investigations were undertaken whether the growth of Candida albicans is influenced by glucose, altered the serum factors and the granulocytes in diabetes mellitus. The rats were grouped into the normal, alloxan-diabetic, insulin-treated groups and bred with the commercial diets for 8 days. In the normal and insulin-treated groups, the body weights were gained 26 gm and 18 gm respectively, but in the alloxan-diabetic groups, the weights were lost 15 gm. The plasma glucose concentrations in the normal, alloxan-diabetic and insulin-treated groups were 153 ± 5 ㎎%, 386 ± 7㎎%, 114 ± 2㎎%. The growth rates of Candida albicans in the alloxan-diabetic groups were 1.18 ± 0.01 (1hr), 1.36 ± 0.02 (2hrs), 1.67 ± 0.03 (3hrs), 2.01 ± 0.07 (4hrs). These results were significantly higher than those of the normal groups (p < 0.05). In insulin-treated groups, the growth rates of Candida albicans were 1.13 ± 0.01 (1hr), 1.25 ± 0.01 (2hrs), 1.44 ± 0.01 (3hrs), 1.46 ± 0.01 (4hrs). These were significantly lower than those of the alloxan-diabetic groups (p < 0.05). The growth rates of C. albicans showed no significant difference between the normal and the insulin-treated groups. In the high glucose groups (400 ㎎%), the growth rates showed little difference with the normal, alloxan-treated, insulin-treated groups. In the control groups which had no added serum, the growth rates were much higher than those of the other experimental groups. The actual doubling time calculated from the growth curves obtained from the experimental groups revealed that the control groups without added serum (3.52 ± 0.07 hrs) were the shortest of all diet groups and alloxan-diabetic groups were the next. These results suggest that the growth rates of Candida albicans were influenced by some factors in serum and these factors might be decreased or impaired in the diabetic animals and through the administration of the insulin, these factors seemed to be recovered in serum. Also the glucose alone might not be the contributing factor for Candidal growth. The pagocytic capacities of the granulocytes showed no difference between the experimental groups. However, the killing capacities of the granulocytes from alloxan-diabetic groups were significantly lower as compared to the normal and insulin-treated group (p < 0.05). The specific activities of the myeloperoxidase were the same in the normal, alloxan-diabetic and insulin-treated groups. However, the protein volume were significantly lower in the alloxan-treated groups as compared to the normal and insulin-treated groups (p < 0.05). These results suggest that in diabetes mellitus, the phagocytic capacities are not altered but the intracellular killing capacities are decreased. Myeloperoxidase, one of the intracellular defense enzymes, was not changed in diabetes mellitus, but the protein volume in diabetic granulocyte which affectes on the myeloperoxidase concentration were decreased because of the lack of insulin in the alloxan-diabetic rats which leades to the generalized decrease in the intracellular killing activity of the granulocytes.

      • KCI등재

        口腔內 囊尾蟲症 一例

        Shin Jung Cha(車信正),Dai Suck Oh(吳大錫),Han Joon Choi(崔漢俊) 대한구강악안면외과학회 1982 대한구강악안면외과학회지 Vol.8 No.1

        A 37-year-old woman was admitted to dental dept., Seoul Red-Cross Hospital on 14th Oct. 1981 for treatment of small cystic formation on the mucosa of the lower lip. There was no subjective symptoms and 0.9×1.2 cm. sized mass showed mobile, slight hardness and no tenderness on palpation and no tendency to increase for two years. The cystic mass was removed by surgical intervention under clinical diagnosis of retention cyst. Histopathologically, cystic capsule contained a cysticercus of Taenia solium. Internal organ of this worn1 began degeneration and tissue reaction showed a diffuse histiocytic proliferation in inner zone and well formed collagenized capsule in outer zone. Final diagnosis revealed cysticercosis, intermediated stage.

      • KCI등재

        영양염류의 유입농도와 수리학적 체류시간에 따른 달뿌리풀 ( Phragmites japonica Steudel ) 의 질소와 인 제거능

        신정이(Jung Yi Shin),영일(Young Il Cha) 한국환경생물학회 1999 환경생물 : 환경생물학회지 Vol.17 No.2

        Uptakes of N and P by Phragmites japonica Steudel. are dtermined in continuous flow tanks as a function of hydraulic retention time(HRT, days) and nutrient concentration(NC). Results show that the uptake was higher at shorter HRT and higher nutrient concentration, and the regression equations were estimated. Mean above ground biomass of Phragmites japonica in the middle reaches of Sagimak stream was 335.92g/㎡, and estimated uptake by this vegetation were 7.31∼20.15 HN_4∼N, 31.15∼95.84 NO_3∼N, and 4.09∼11.48 PO_4-P ㎎/㎡/day in Sagimak stream, respectively when HRT was 1∼5 days. According to this study, it is concluded that Phragmites japonica Steudel. are suitable for water quality improvement of stream through nutrient uptake at short HRT and high concentration.

      • KCI등재

        갯버들 ( Salix gracilistyla Miq. ) 의 질소와 인 제거능

        신정이(Jung Yi Shin),영일(Young Il Cha) 한국환경생물학회 1999 환경생물 : 환경생물학회지 Vol.17 No.4

        Removal efficiency and potential of N and P by Salix gracilistyla Miq. are determined in continuous flow tanks as a function of hydraulic retention time(HRT, days) and nutrient concentration (NC). Results show that the removal efficiency was longer HRT and lower nutrient solution. And also removal potential was higher at shorter HRT and higher nutrient concentration, and the regression equations were estimated. Mean above ground biomass of Salix gracilistyla Miq. in the middle reaches of Suip stream was 4880.81g/㎡, and estimated removal by this vegetation from biomass and estimated equation above were 0.49∼15.49 NH_4-N ㎏/day, 5.83∼405.39 NO_3-N ㎏/day, 7.57∼23.22 PO_4-P ㎏/day in Suip stream, respectively when HRT was 0.59∼5.21, inflow concentration was 0.05∼0.4, ㎎/L NH_4-N, 1.42∼11.36 ㎎/L NO_3-N, 0.1∼0.27 ㎎/L PO_4-P. According to this study, it is concluded that Salix gracilistyla Miq. are contribute by their high biomass and for water quality improvement of stream through nutrient removal potential. [Salix gracilistyla Miq., Removal efficiency, Uptake, Hydraulic retention time(HRT), Concentration].

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