점액성췌장 낭종 1예

황석주,김영운,오성광,김대영,임선재,박승욱,이두용,이헌영 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Pancreatic cystadenoma is very rare, slow growing tumor and generally preoperative differential diagnosis may be difficult. A 43-year-old female was admitted to our hospital with the complaint of abdominal discomfort in the epigastrium for about preceeding 5 years. Ultrasonography and Computed tomography were performed. When endoscopic retrograde cholangio-pancreatogram was performed, displacement of distal pancreatic duct by huge mass was noted and injected dye was drained irregulary into the cavity of mass. Distal pancreatectomy was performed with splenectomy. The mass size of distal pancreas was 7X4cm, and the cyst contained with yellowish thick mucoid fluid. Diagnosis was confirmed the mutinous cystadenoma of the pancreas on histologic examination.

통행분포기법의 적용과 평가에 관한 연구

오재화,황의진,진용선 朝鮮大學校 建設技術硏究所 2001 建設技術硏究 Vol.21 No.1

This study has an object of searching for appropriateness in applying the trip distribution model by studying the changes of the character of parameter which the model contains and by analyzing and evaluating trip distribution technique out of four steps of pre-estimate technique for the traffic demand through computer simulation centering around Kwangju. Method of this study is investigating the basic theory for trip distribution model and with this grounding, I rearranged it as research data for trip distribution model compatible for Kwangju, using data such as research data on actual state, the statistics annual report and basic plan for traffic full equipment of Kwangju. So, The most stable measure of the type of trip distribution of Kwangju city was produced in Fratar and Detroit model, however, gravity model has a little bit low reliance in sharing of estimation and actual survey although it is astringent in short period.

特用資源植物의 硏究 : 한국임학회지에 게재된 논문을 중심으로 Based on the Articles Published in the Journal of Korean Forestry

이재선,김철우,배찬호,송재모,강효진,황석인,문흥규 江原大學校 森林科學硏究所 2003 Journal of Forest Science Vol.19 No.-

한국임학회지 (1962년의 1호~2002년의 91권 6호)에 게재된 특용자원식물 관련 논문에서 식·음용식물, 약용식물, 사료식물, 조경식물, 섬유식물, 산업용식물 및 밀원식물로 분류하고 그 내용에 따라 입지환경, 생태, 생리, 번식, 조림(또는 무육, 재배), 유전·육종, 분류(또는 식별), 병·충해와 방제, 동물피해와 방제, 성분분석, 식생정보, 생물공학, 경영·경제 및 총설로 나누었다. 총 1,434편의 발표 논문 중 유용식물자원을 대상으로 한 논문은 27.6%를 차지하는 396편이었고, 내용은 식생정보 60편(15.2%), 생리 56편(14.1%), 유전·육종 56편(14.1%), 번식 53편(13.4%) 및 생태 37편(9.3%)이었다. 조림(무육·재배)은 11편(2.8%)으로 특용자원식물의 규모경영이 이루어지지 않고 있음을 시사하고 있으며, 이것은 경영·경제 분야가 6편(1.5%)인 것과 맥을 같이 하고 있었다. 연구대상 식물은 잣나무(42편), 아까시나무(23편), 밤나무(14편) 및 은행나무(14편) 순으로 높았고, 이 식물들과 관련한 연구내용은 번식, 생리, 유전·육종, 생태 및 병·충해 순이었다. 연구의 목적, 내용, 결과 및 대상식물 등을 고려하여 보면, 1) 초본식물에 대한 보다 많은 연구, 2) 타산업 또는 학분 분야와의 공동연구, 3) 자원 보전적 연구 및 4) 연구주체자 간의 연구결과의 공유 등이 매우 요망된다. The articles, published in the Journal of Korean Forestry from Number 1(1962) to number 6, Volume 91(2002), were surveyed and investigated for the research trend analysis about resource-plants for special use or purpose, i.e edible plants, medicinal plants, feed resource, landscape plants, fiber plants, industrial usage, and bee plants. If the purpose or subject matter of the research was construction or furniture timber production, mushrooms and/or pulp and Paper, such research was not included in this study. These articles were classified again depending on the content of research into 14 categories : habitat environment, ecology, physiology, propagation, silviculture(tending and culture), genetics and breeding, identification, insect and disease control, animal-related research, cemponent analysis, vegetation survey, biotechnology, management, and review. Among the total 1,434 articles published, 396 ones (27,6%) were related with plants for special use or purpose. Vegetation survey was 60(15.2%) ; physiology 56(04.1%) ; genetics and breeding 56(14.1%) ; propagation 53(13.4%) ; and ecology 37(9.3%). Siviculture research field included 11 articles (2.8%), which indicates that the management of resource-plants is to far from economic income as seen in the low number of management research filed articles, i. e., only 6 reports(1.5%). Korean white Pine was most popular for research and included 42 articles ; Robinia pseudoacacia 23 Castanea crenata 14 : and ginkgo tree 14, Research related with these species had focused mainly or propagation, physiotogy, genetics and breeding, ecology and pest control. Based on this survey and analysis, the followings are suggested : 1. More research is required on forest herbaceous plants. 2. Cooperative research work with other industrial and/or scientific area is recommendable for commercialization including medicine, cosmetics, and food etc. 3. Research resource-plant conservation. which includes biology, social education and policy, should be supported for next generation. 4. Mutual correspondence and information exchange about the research results between researchers and institutes is more necessary than now.

LPE법으로 작성한 산화물초전도체 Bi₂Sr₂-Ca₁+Cu₂ 막(films) 의 초전도특성

신재수,황선아,이종용,이권재 대전대학교 기초과학연구소 1997 自然科學 Vol.8 No.2

LPE(Liquid press epitaxy)법을 이용하여, Sr과 Ca가 서로 상호 치환된 산화물초전도체 Bi₂Sr₂??Ca₁+x??Cu₂O??(x?=0, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6) 막(film)을 작성하여 상호치환 상태와 초전도특성과의 관계를 알아보았다. 작성한 막(film)의 조성비은 융액조성비(x?)와 막(film)속의 조성비(x?)가 비례함을 알 수 있었고, c-축으로 강하게 배향된전형적인 Bi2212상의 단일상(singe-phase)을 보였다. 치환량 x?의 증가에 따라, 임계온도 T??, c-축의 길이, carrier농도 등은 단조로이 감소하고 있음을 알 수 있었다. We investigated the superconductivity of Bi₂Sr₂_Ca₁+x?Cu₂O?+?x?=0, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6) films by liquid phase epitaxial method. X-ray diffraction measurements revealed that films were predominantly oriented with the c-axis perpendicular to the substrate surfaces. The zero-resistance temperature and the lattice parameter c linearly decreased with the increase of x?, corresponding to the decrease of the carrier concentration.

Fermentation-Mediated Enhancement of Ginseng’s Anti-Allergic Activity against IgE-Mediated Passive Cutaneous Anaphylaxis In Vivo and In Vitro

( Seon-weon Hwang ),( Xiao Sun ),( Jun-hyuk Han ),( Tae-yeon Kim ),( Sushruta Koppula ),( Tae-bong Kang ),( Jae-kwan Hwang ),( Kwang-ho Lee ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.10

Ginseng (the root of Panax ginseng Meyer) fermented by Lactobacillus plantarum has been found to attenuate allergic responses in in vitro and in vivo experimental models. Ginseng has been reported to also possess various biological functions including anti-inflammatory activity. The present study was aimed at comparing the anti-allergic effect of ginseng and fermented ginseng extracts on IgE-mediated passive cutaneous anaphylaxis in vitro in a murine cell line and in vivo in mice. Fermented ginseng extract (FPG) showed higher inhibitory effect against in vitro and in vivo allergic responses when compared with ginseng extract (PG). The secretion of β-hexosaminidase and interleukin (IL)-4 from the IgE-DNP-stimulated RBH-2H3 mast cells were significantly (p < 0.05) inhibited by FPG treatment, and this effect was concentration-dependent. Further, MKK4 activation and subsequent JNK phosphorylation were attenuated by FPG treatment. The inhibitory effect of FPG on the in vitro allergic response was verified in vivo against IgE-DNP-induced passive cutaneous anaphylaxis in a mouse model. These data indicated that the fermentation of ginseng with L. plantarum enhanced its anti-allergic effects both in vitro and in vivo. We predict that compositional changes in the ginsenosides caused by the fermentation may contribute to the change in the anti-allergic effects of ginseng. The results of our study highlight the potential of the use of FPG as a potential anti-allergic agent.

Clinical course of patients who developed tuberculosis (TB) after receiving tumor necrosis factor (TNF)-α inhibitors

( Seon-hye Kim ),( Boksoon Chang ),( Jae Joon Hwang ),( In Kyoung Hwang ),( So Hee Park ),( Yee Hyung Kim ),( Cheon Woong Choi ),( Jee Hong Yoo ),( Hong Mo Kang ),( Myung Jae Park ) 대한결핵 및 호흡기학회 2015 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.120 No.-

Background: The uses of the tumor necrosis factor- α inhibitors increase the risk of developing TB. However, there is limited information about the clinical outcomes of active TB followed by TNF inhibitors and the appropriateness of TNF inhibitors readministration. Thus, we analyzed the clinical characteristics and treatment response of patients who developed TB after treating TNF inhibitors. Methods: We retrospectively reviewed all patients diagnosed with active TB after receiving TNF inhibitor from January 2001 through August 2015 at two academic hospitals in Korea. Outcomes were assessed via the medical records, bacteriological and radiologic findings and the response to anti-TB treatment. Results: 23 patients(1.4%) developed TB during a median of 316 days of TNF inhibitors. The LTBI screening was performed in all 23 patients and LTBI was diagnosed in 4 patients. In these patients, TB disease occurred even after LTBI treatment. Favorable course were showed in 21(91%) of 23 patients after administering first-line anti-TB medication, although 2 patients developed MDR TB. The 10 patients were retreated with TNF inhibitors: 6 patients were restarted during anti-TB treatment and the other 4 patients were reinitiated after completion of anti-TB medication. No TB recurrence was reported in the patients of resuming TNF inhibitors during a median follow-up of 26 months. Conclusions: We suggest that more specific protocol for diagnosis of LTBI and TB is required before and during TNF inhibitors. And recommencing TNF inhibitors may be considered and safe during the anti-TB medication

Characterization of Angiogenesis Inhibitor Effect of Green Tea Seed Extract

Hwang, Jae-Ho,Lee, Sung-Hoon,Rha, Sung-Ju,Yoon, Ho-Seop,Shin, Jin-Hyuk,Lee, Jin-Hee,Seo, Myeong-Jin,Kang, Kyeong-Wan,Han, Kyeong-Ho,Kim, Yong-Joo,Kho, Kang-Hee,Kim, Seon-Jae,Shin, Tai-Sun The Korean Society for Integrative Biology 2009 Animal cells and systems Vol.13 No.2

Green tea seed was extracted with absolute ethanol,and the green tea seed extract(GTSE)was subjected to assays for toxicity, antioxidant ability, angiogenesis inhibitory effects and cell adhesion, as well as western blotting, and an in vivo experiment against 4 high-ranking adult cancers in Korea. Our series of experimental data demonstrated that GTSE has an antioxidant ability superior to that of EGCG in the green tea leaf, and also exhibits a profound high tumor growth inhibitory activity on a variety of cancer cell lines, as well as nude mice infected with cancer cells. GTSE was identified as a natural anticancer compound showing excellent angiogenesis inhibition and cancer cell suppression abilities. Our preliminary observations also indicate that GTSE may be another potential source of natural dietary antioxidants and also may be applicable as a novel natural anticancer agent.

Dietary green tea extract improves growth performance, body composition, and stress recovery in the juvenile black rockfish, Sebastes schlegeli

Hwang, Jae-Ho,Lee, Si-Woo,Rha, Sung-Ju,Yoon, Ho-Seop,Park, Eun-Sik,Han, Kyeong-Ho,Kim, Seon-Jae Springer-Verlag 2013 Aquaculture international Vol.21 No.3

군평선이, Hapalogenys mucronatus의 형태 및 골격

민재원(Jae Won Min),윤빛나(Bit Na Youn),한경호(Kyeong Ho Han),김선재(Seon Jae Kim),정현호(Hyun Ho Jeong),황재호(Jae Ho Hwang),이성훈(Sung Hun Lee),라성주(Sung Ju Rha) 전남대학교 수산과학연구소 2012 수산과학연구소논문집 Vol.20 No.-

농어목 하스돔과에 속하는 군평선이의 형태 및 골격을 조사하기 위하여 2008년 4월부터 2008년 6월까지 여수 금오도 주변 해역에서 새우조망에 채포된 어체를 여수 군내리 어판장에서 구입하였다. 표본의 형질을 조사하기 위하여 외부형태를 관찰 한 후 계수ㆍ계측하였으며, 골격의 형태는 삶아서 채골하여 관찰하였다. 군평선이의 외부형태는 몸이 황갈색 바탕에 너비가 넓은 6개의 암갈색 가로줄 무늬가 있으며, 가장 앞의 줄무늬는 눈을 가로 지르고 가장 뒤의 줄무늬는 미병부에 위치하였다. 등지느러미 줄기수는 극조가 11개, 연조가 16~17개였고, 뒷지느러미는 극조가 3개, 연조가 10개였으며, 가슴지느러미는 연조 17~18개, 배지느러미는 극조가 1개, 연조가 5개, 꼬리지느러미 줄기수가 17~18개였다. 두개골을 등쪽에서 보았을 때 형태는 뱀의 머리를 닮아 있고 앞뒤로 길게 늘어져 있으며 앞쪽은 다소 오목한 형태를 띤다. 전상악골은 상행돌기의 위 가장자리는 비교적 넓고 뭉툭하며, 후반부에도 후상행돌기가 있고, 전상악골이 치골보다 조금 더 길며, 이빨이 발달되어 있다. 전새개골은 앞부분이 두텁고 반달모양을 하며, 뒤 부분에는 톱니모양의 날카로운 돌기가 있다. 새궁부에서 새조골은 5개로 이루어져 있고 길이가 길고 두터우며, 각설골과 하설골에 연결되어 있다. 견대부의 상쇄골과 쇄골은 T-자형으로 연결되어 있고, 척추골의 복추골은 9개, 미추골은 총12개이며 각 추체들은 돌기가 있어 견고하게 결합되어 있다. The Belted beard grunt, Hapalogenys mucronatus of the family Pomadasyidae were colleted by Guem-o-do coastal in Yeosu, April~June 2008. This species is color of the body; covered with graybrown and the line on the body is black color. Dosal fin rays 16~17; pectoral fin rays 17~18; anal fin rays 10; caudal fin rays 17~18; ventral fin rays 5. Measurement for ten specimen (144~154mm SL) in hundredths of standard length; head length 33.3%; pectoral fin length 24.4%; dosal fin length 28.6%; caudal peduncle length 15.3%; caudal peduncle depth 13.4%. Skull is looks like snakes head, long and the front of concave. premaxillary dge of bumps is comparatively wide and the latter half premaxillary. premaxillary is dentray than to long. The preopercle has thick semicircular front part and sharp bump at rear. The branchiostegalray is composed thick and long five bones, and connected the ceratohyal and hypohyal in operculum. The supracleithrum and cleitrum are connected T-shape in the shoulder girdle. Nine abdominal and twelve caudal vertebrae are strongly combined and each centrum has bump in vertebrae.

녹차추출물의 Vibrio parahaemolyticus에 대한 항균활성

김선준(Seon-Jun Kim),황재호(Jae-Ho Hwang),한경호(Kyeong-Ho Han),조정용(Jeong-Yong Cho),마승진(Seung-Jin Ma),김두운(Duwoon Kim),문제학(Jae-Hak Moon),박근형(Keun-Hyung Park),김선재(Seon-Jae Kim) 한국차학회 2010 한국차학회지 Vol.16 No.2

Green tea extract was tested to determine its antimicrobial effects against the pathogenic bacteria Vibrio parahaemolyticus. The antimicrobial effect of green tea extract was evaluated by measuring the change in the concentration level of V. parahaemolyticus genomic DNA, which was obtained after treatment of green tea ethanol extract with neutral and acidic solvent-fractionation. Green tea extract of the neutral fraction showed concentration-dependent killing of V. parahaemolyticus, whereas green tea extract of the acidic fraction significantly inhibited the growth of V. parahaemolyticus at the minimum inhibitory concentration of 1,000~1,500 ppm.