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      • KCI등재

        Superconducting MgB2 Wire Drawing Considering Anisotropic Hardening Behavior and Hydrostatic Effect

        Young‑Seok Oh,Ho Won Lee,Kook‑Chae Chung,Duck‑Young Hwang,Seong‑Hoon Kang,Jeong Whan Yoon 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

        Numerical modeling was conducted to investigate the deformation behavior of powder mixture during multi-pass drawingprocesses for multi-filamentary MgB2wire. A modified Drucker-Prager Cap (DPC) model with an elliptical cap surface usingthe new material characterization method was developed to capture the anisotropic hardening behavior and hydrostatic effectof the powder mixture. A number of uniaxial die compaction, cold isostatic pressing, diametrical compression, and uniaxialcompression tests were conducted using different powder densities to characterize the modified DPC model. A commercialfinite element software ABAQUS with a user subroutine was used to simulate the drawing of the MgB2wire. The densityand area fraction of the powder mixture during the wire-drawing process were verified with experimental results. The differencein packing density at the inner and outer filaments of the MgB2wire was successfully captured by simulation. Inaddition, the effect of the initial packing density on the superconducting properties of MgB2wire was numerically studied. It is shown that the increase in the superconducting area, which results from a high initial packing density, should be moreeffective compared to the increase in the grain connectivity in enhancing the critical current properties for the MgB2wirewhen the final packing density is saturated after a number of drawing processes.

      • 통풍형 방음벽 개발 및 적용에 관한 연구

        윤제원(Je-Won Yoon),김영찬(Young-Chan Kim),김금모(Keum-Mo Kim),장강석(Kang-Seok Jang),구본성(Bon-Sung Ku),엄주용(Joo-Yong Eom) 한국소음진동공학회 2011 한국소음진동공학회 학술대회논문집 Vol.2011 No.10

        The purpose of this study is to develop an air-passing soundproofing panel with more improved structure to reduce the CO2 emission and installation cost. To reduce the emission of CO2 ; it is suggested to choose low CO2 emission material relative to the aluminum and to reduce the materials by developing a specially designed air-passing soundproofing panel structure. First of all, we performed the flow analysis to predict the wind pressure according to the open angle of the air-passing soundproofing panel and the noise level analysis at the receiver point. To verify the simulation, a prototype of the soundproofing panel was made. The flow test in the wind tunnel and load test were performed. The economic evaluation for the installation of the air-passing soundproofing panel was performed and specifications of the installation was prepared. As the results of this research, it was verified that the wind load was reduced about 40% to that of the conventional one at 25m/s wind speed in the wind tunnel test. By applying the 4m span soundproofing wall with air-passing soundproofing panel and under the cost of 250 thousand won/m2 instead of the conventional 2m span panel, the installation cost will always be lowered than the conventional one in the combination of (60:40~50:50) conventional to air-passing soundproofing panel from the economic evaluation. The 20% reduction of CO2 was found by changing the 50% of aluminum soundproof panel to air-passing soundproofing panel.

      • KCI등재

        제주물을 이용한 기능성 및 혼합음료의 개발방향 설정에 관한 연구

        고성보(Ko, Seong-Bo),현창석(Hyun, Chang-Seok),강경원(Kang, Kyung-Won) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.5

        세계적으로 건강기능식품의 주변 환경은 매우 빠르게 변하고 있다. 2012년 세계기능성 음료시장은 269억달 러 규모, 아태지역 시장은 136억달러 규모가 될 것으로 전망하고 있다. 국내 먹는 샘물 시장은 2008년 4,400억원 규 모를 형성하고 있고, 제주삼다수의 매출액은 891억원이다. 그러나 “제주삼다수”라는 브랜드는 한계성을 지니고 있다. 이에 대한 방안으로 제주물의 품질 우수성을 알리는 포괄적인 광고가 필요하며, 제주 물을 이용한 기능성 음료 및 혼 합음료 개발의 성공 가능성을 높이기 위해서 제주워터(Jeju Water)라는 글로벌 통합브랜드 개발이 필요하다. 기능성 및 혼합음료 제품개발시 제주지역의 농산물의 기능성을 적극 활용해 물산업과 제주의 1차산업을 연계해 농산물의 과 잉생산 처리와 고부가가치화를 촉진시킬 필요가 있다. The environment of the health food in the world has been changed very rapidly. The world market volume of functional drinks in 2012 will be estimated at $ 26.9 billion, and Asia-Pacific market is expected to be $ 13.6 billion. The domestic market volume of bottled water in 2008 was 440 billion won, and "Jeju Samdasu" sales was 89.1 billion won. But the brand of "Jeju Samdasu" has the limits. As a solution, the comprehensive advertising of the excellence quality of Jeju water is required. To increase the likelihood of success in development of functional and mixed drinks by the water is necessary to develop a global integrated brand. In developing the functional and mixed drinks by the water, we apply the functionality of the Jeju agricultural products actively, and connect Jeju Water industry with Jeju agricultural industry, which promote the overproduction control and the high value- added agricultural products.

      • SCISCIESCOPUS

        Magnetic Resonant Three-Coil WPT System Between Off/In-Body for Remote Energy Harvest

        Kang, Seok Hyon,Choi, Jung Han,Harackiewicz, Frances J.,Jung, Chang Won THE INSTITUTE OF ELECTRICAL ENGINEERS 2016 IEEE Microwave and Wireless Components Letters Vol. No.

        <P>In this letter, the effect of the human body in a magnetic resonance wireless power transfer (MR-WPT) system for wearable and implantable devices is studied. To implement the experiment, muscle-mimicking liquid is configured with parameters similar to those of the human body. The transmitter part is located outside the human body (in the air), and the receiver part is implanted in the liquid. The proposed 3-coil MR-WPT system, which operates at 6.78 MHz shows effectively higher transfer efficiencies compared with a 4-coil MR-WPT system at near transfer distance which is the predicted position for a pacemaker. The results indicate that the proposed system with optimized receiver using air-pocket has potential applications in off/in-body devices that benefit from remote energy harvesting, especially at near distances such as pacemakers.</P>

      • Postoperative Radiation for Soft Tissue Sarcoma

        Kang,Yong-Koo,Kim,Hyoung-Min,Bahk,Won-Jong,Lee,Seong-Koo,Kim,Yun-Sil,Kim,Jung-Mang,Moon,Myung-Sang,Woo,Young-yun,Chang,Jee-Young,Yoon,Se-Chul,Song,Seok-Whan 가톨릭중앙의료원 가톨릭암센터 1994 암심포지움 Vol.- No.2

        To evaluate the role of radiation and chemotherapy after limb-saving operation in the management of soft tissue sarcoma, the authors analysed retrospectively 33 patients treated in Department of Orthopaedic Surgery and Radiation Therapy, Catholic University Medical College, in terms of survival rate, local recurrence and prognostic factors. The sex distribution was 16 males and 17 females. The age distribution ranged from 16 to 81 year old with mean age of 48. The follow-up period ranged from 1 year to 10 years with average of 5.5 years. The histologic diagnoses were 9 liposarcoma(27.2%), 8 MFH(24.2%), 7 unclassifiable(21.2%), 3 rhabdomyosarcoma(9.1%), and 3 fibrosarcoma(9.1%) in orders. While marginal and intralesional margins were gained in 24 patients(72.2%), wide and radical margins were obtained only in 9 patients(27.3%). On postoperative 3 weeks, local irradiation of 5000-7000 cGy was delivered to all patients by shrinking field technique for 5-8 weeks. Of 33 patients, 16(45.5%) patients were recieved adjuvant chemotherapy in combination of adriamycin, cyclophosphamide & vicristine, or VP16 & ifosfamide based on histologic type and obtained surgical margin. The survival rates at 2 years and 5 years were 58% and 37% respectively. Local recurrences occured in 15 patients(45.5%) at average 16 months after operation. In addition, the authors considered surgical margin, presence of local recurrence and tumor size as a significant prognostic factors.

      • KCI등재

        Expression and Distribution of Free Zinc in Penile Erectile Tissue

        Kang Beom Seok,Suh Sang Won,Yang Dae Yul,Choi Bo Young,Lee Won Ki 대한남성과학회 2023 The World Journal of Men's Health Vol.41 No.1

        Purpose: Several studies have shown that zinc has a significant influence on erectile function. However, no studies evaluating the cellular distribution of free zinc in penile erectile tissue have been performed. Therefore, this study aimed to test whether free zinc is present in penile tissue and whether it may be involved in the electrical stimulation (ES)-induced penile erection. Materials and Methods: The subjects for this study were 26 young (8-week-old) male C57BL/6J mice. After the cavernous nerve was exposed through a midline stomach incision, 14 mice received ES of the cavernous nerve (ES group), whereas 12 mice did not (control group). Intracavernous pressure (ICP) (consisting of 10 V at a duration of 1 min, frequency of 12 Hz and a pulse width of 1 m/s) was recorded during ES. Immediately after ICP was recorded, penile tissues were harvested for histo-logical and biochemical analysis, including analysis of zinc transporter 3 (ZnT3) and intracellular free zinc levels. Results: The expression of neuronal nitric oxide synthase (nNOS) and endothelial NOS (eNOS) in penile tissue was significantly greater in the ES group than in the control group (p=0.036 and 0.016, respectively). And then, ZnT3 and intracellular free zinc were present in the penile tissue of both groups. However, ZnT3 immunofluorescence in the ES group was more intense in the dorsal nerve bundle (22% increase, p=0.032). The ES group also showed higher intensity N-(6-methoxy-8-quinolyl)-para-tolu-enesulfonamide (TSQ) fluorescence signals indicative of intracellular free zinc level in the penile tissue compared to the control group (49% increase in dorsal nerve bundle, p=0.001; 50% increase in corpus cavernosum, p=0.001). Conclusions: The results of the study supported the expression and distribution of free zinc in penile tissue and increased levels after penile erection. Therefore, this study provides anatomical evidence for the potential role of free zinc in penile erection.

      • Molecular Progression Risk Score for Prediction of Muscle Invasion in Primary T1 High-Grade Bladder Cancer

        Kang, Ho Won,Seo, Sung Pil,Byun, Young Joon,Piao, Xuan-Mei,Kim, Ye-Hwan,Jeong, Pildu,Ha, Yun-Sok,Kim, Won Tae,Kim, Yong-June,Lee, Sang-Cheol,Moon, Sung-Kwon,Choi, Yung-Hyun,Yun, Seok-Joong,Kim, Wun-Ja Elsevier 2018 Clinical genitourinary cancer Vol.16 No.4

        <P><B>Abstract</B></P> <P><B>Background</B></P> <P>Pathologic T1 high-grade (pT1HG) bladder cancer (BC) is characterized by a high progression rate and constitutes an important clinical challenge; however, there is no consensus on the prediction of progression in pT1HG BC. The purpose of this study was to validate previously published molecular progression risk score (MoPRS) for predicting muscle-invasive disease in pT1HG BC.</P> <P><B>Materials and Methods</B></P> <P>The expression of an 8-gene progression-related classifier identified from microarray data was analyzed by real-time PCR, and the MoPRS was calculated in 121 newly recruited patients with pT1HG BC. Progression was defined as muscle invasion or metastasis.</P> <P><B>Results</B></P> <P>Overall, the disease of 28 patients (23.1%) progressed to muscle-invasive BC during the median follow-up of 63.7 (interquartile range, 17.6-96.4) months. The MoPRS was significantly higher in 1973 World Health Organization grade 3 than grade 2 tumors (<I>P</I> = .004). Early development of invasive BC was more prevalent in the highest quartile MoPRS group than in the lowest to 75th percentile MoPRS groups according to Kaplan-Meier analysis. Multivariate Cox regression analysis revealed that the MoPRS was an independent predictor of invasive BC, either as a continuous variable (hazard ratio, 1.624; 95% confidence interval, 1.266-2.082; <I>P</I> < .001) or as a categorical variable (hazard ratio, 3.089; 95% confidence interval, 1.335-7.150; <I>P</I> = .008).</P> <P><B>Conclusion</B></P> <P>The MoPRS was an independent prognostic factor for identifying patients at high risk of invasive BC in patients with pT1HG BC. This scale may help identify patients who could benefit from more aggressive therapeutic intervention such as early cystectomy.</P>

      • Effect of Mechanical Ventilation Mode Type on Intra- and Postoperative Blood Loss in Patients Undergoing Posterior Lumbar Interbody Fusion Surgery: A Randomized Controlled Trial

        Kang, Woon-Seok,Oh, Chung-Sik,Kwon, Won-Kyoung,Rhee, Ka Young,Lee, Yun Gu,Kim, Tae-Hoon,Lee, Suk Ha,Kim, Seong-Hyop by 2016, the American Society of Anesthesiologists 2016 Anesthesiology Vol.125 No.1

        <P>Background: The aim of study was to evaluate the effect of mechanical ventilation mode type, pressure-controlled ventilation (PCV), or volume-controlled ventilation (VCV) on intra-and postoperative surgical bleeding in patients undergoing posterior lumbar interbody fusion (PLIF) surgery. Methods: This was a prospective, randomized, single-blinded, and parallel study that included 56 patients undergoing PLIF and who were mechanically ventilated using PCV or VCV. A permuted block randomization was used with a computer-generated list. The hemodynamic and respiratory parameters were measured after anesthesia induction in supine position, 5 min after patients were changed from supine to prone position, at the time of skin closure, and 5 min after the patients were changed from prone to supine position. The amount of intraoperative surgical bleeding, fluid administration, urine output, and transfusion requirement were measured at the end of surgery. The amount of postoperative bleeding and transfusion requirement were recorded every 24 h for 72 h. Results: The primary outcome was the amount of intraoperative surgical bleeding, and 56 patients were analyzed. The amount of intraoperative surgical bleeding was significantly less in the PCV group than that in the VCV group (median, 253.0 [inter-quartile range, 179.0 to 316.5] ml in PCV group vs. 382.5 [328.0 to 489.5] ml in VCV group; P < 0.001). Comparing other parameters between groups, only peak inspiratory pressure at each measurement point in PCV group was significantly lower than that in VCV group. No harmful events were recorded. Conclusion: Intraoperative PCV decreased intraoperative surgical bleeding in patients undergoing PLIF, which may be related to lower intraoperative peak inspiratory pressure.</P>

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