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PARAGONIMUS INVATION OF THE LUNG OF A CAT
Schofield Frank W.,Paik Chong Bum Korean Veterinary Medical Association 1961 대한수의사회지 Vol.5 No.1
The first case in Korea of Paragonimus westermanni(Human lung fluke) in the cat is recorded with gross-histo-pathological findings.
The Comparative Evaluation of Soil Removal
Schofield-Tomschin, Sherryl A.,Kadolph, Sara J.,Kwon, Young-Ah 한국의류학회 2003 한국의류학회지 Vol.27 No.12
본 연구의 목적은 기계에 의한 객관적 오염제거 평가와 육안에 의한 주관적 오염제거에 평가를 비교하기 위한 것이다. 본 연구를 위해 백색의 순면직물과 65%/35% 폴리에스테르/면 직물 시료에 9가지의 오염을 각각 처리한 오염포를 제작한 후, 세탁 실험을 하였다. 주관적 오염제거의 평가는 오염시키지 않은 포를 기준시료로 하여 오염포와 같은 조건으로 세탁한 후, 오염제거도를 AATCC Gray Scale for STaining으로 평가하였다. 세탁 후 오염제거도를 객관적으로 평가하기 위해서 각 시료의 K/S values, CIELAB, CMC, ASTM, E313 Whiteness Index(WI), ASTM E313 Yellowness Index, and CIE tristimulus values를 구하였고 세탁에 의한 control 시료의 반사율 변화에 대한 오염포의 반사율 변화를 비교한 오염제거울(PSR)을 구하였다. 육안에 의한 주관적 평가 결과와 기계에 의한 객관적 평가의 결과와의 관계를 파악하고자 상관분석을 실시하였다. 본 연구결과, 주관적 평가와 객관적 평가 사이에 유의적인 상관관계가 확인되었으며, 주관적 평가 결과 중 WI가 주관적 평가 결과와 가장 상관관계가 높았으며, PSR과 주관적 평가 결과와의 상관이 상대적으로 가장 낮은 것으로 나타났다. 따라서 백색포의 오염 판정이 필요한 산업체에서 현재 많이 사용하고 있는 PSR 보다는 WI나 다른 색차를 이용하여 객관적 오염 평가를 하는 것이 주관적인 오염평가 결과에 더 근접할 수 있음을 알 수 있었다.
Projecting the Radiation Oncology Workforce in Australia
Schofield, Deborah,Callander, Emily,Kimman, Merel,Scuteri, Joe,Fodero, Lisa Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4
Research on radiation oncologists has indicated that there is a shortage in supply of specialist workers in this field internationally, and also within Australia. However, there are no current estimates as to what the future Australian radiotherapy workforce will look like. This paper aims to review the current status and capacity of the three main disciplines that make up the radiation oncology workforce in Australia and project the workforce supply and demand for 2014 and 2019. Using data on the workforce from a survey of all radiotherapy facilities operating in Australia in 2008 a workforce model was constructed. This study found that there will be a future shortfall of radiation oncologists, radiation therapists and radiation oncology medical physicists working in radiation oncology treatment. By 2014 there will be 109 fewer radiation oncologists than what will be demanded, and by 2019 this figure will increase to a shortfall of 155 radiation oncologists. There was a projected shortfall of 612 radiation therapists by 2014, with this figure slightly decreasing to a shortfall of 593 radiation therapists in 2019. In 2014, there was projected to be a deficit of 104 radiation oncology medical physicists with a persisting shortfall of 78 in 2019. This future projected shortage highlights the need for radiation oncology workforce planning.
( Alistair Schofield ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2
A 3D geological model was constructed during development of the design for the Kidston Pumped Storage Hydro Project, located in Northern Queensland, Australia. The project utilises two abandoned open-pits and comprises various dams, tunnels, caverns and shafts. The initial model was constructed using project specific geotechnical data including deep boreholes to provide an indication of subsurface geotechnical conditions. Additional data was required to allow further validation of the geological model. Data sources included information saved from disposal by a previous geologist to the mines and also provided data. Loss of records from the mine was significant and borehole files recovered were formatted for use in obsolete software. Data from such files was extracted and “decoded” to allow its use. A significant number of boreholes were primarily for lithological and ore grade purposes. Extraction of useful pieces of information such as fault locations from a combination of digital data and scanned logs was required. Lineament analysis, field mapping of the pits and drone collected photogrammetry data was also utilised to supplement the model. Lessons in data management were learned such as borehole positional information and understandings of “digital data”. Data usage and intellectual property issues were also navigated successfully. The model has assisted in the location of potential faults through the Paleoproterozoic basement rock and assisted in the optimisation of the design. It has utilised traditional and innovative methods of engineering geological data capture. It is also anticipated that the model will be updated during construction to assist with construction planning.
Desmond M. Schofield,Darren N. Nesbeth 한국생물공학회 2017 Biotechnology and Bioprocess Engineering Vol.22 No.4
The use of laboratory procedures is often inefficient for materialisation of recombinant therapeutic proteins in Escherichia coli (E. coli) for pre-clinical evaluation. Approaches such as scaling out shake flask cultivation can be laborious, inefficient and expensive. These inefficiencies can be compounded if the protein requires post-translational modification such as multimerisation. We previously used laboratory methods to produce the < 60 kDa, recombinant biotherapeutic, RB1. We were aware, a priori, that dimerisation of RB1 could double the molecular weight of the protein and increase its systemic retention in the human body by avoiding renal filtration. Here we modified RB1 by substituting a native residue for an unpaired cysteine, generating eRB1, in order to favour its dimerisation. Laboratory methods failed to achieve > 20% disulphide-bridged homodimerisation or monomer of sufficient purity to enable chemi-dimerisation. As such we established a set of high performance, bench-scale, unit operations for cultivation of E. coli cells expressing eRB1, the isolation of eRB1 inclusion bodies, refolding and disulphide-based dimerisation of ≥ 40% of total eRB1 and finally successful chemi-dimerisation of remaining monomeric eRB1. The establishment of scalable procedures can now enable future investigations of eRB1 and other < 60 kDa biologics for which significant bench-scale production is required for pre-clinical evaluation.
REKHA BHARATI,MIKE SCHOFIELD,AKHLESH K. MATHUR 한국펄프·종이공학회 2006 한국펄프종이학회 기타 간행물 Vol.- No.-
The application of specialty chemicals in a pulp mill system for the purpose of problem solving or process enhancement is often demonstrated and supported by data produced in laboratory testing. Hercules Chemical Solutions Pte Ltd., a major specialty chemical supplier to the Asian pulp and paper industry, partnered with the Asian Institute of Technology (AIT) on several occasions to provide insight into the efficacy of proposed chemical treatments designed for local operating conditions and wood species. This paper presents an example of a chemically-assisted deresination project. The resulting surfactant chemistry proved to be a superior deresinator for plantation grown acacia wood and has been successfully implemented in an Asian pulp and paper mill.