Drosophila melanogaster 韓國 自然集團에 있어서 P-M system에 依據한 系統型 轉換

成耆昌,崔喜慶,金溶聲 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.1

Isofemale lines of Drosophila melanogaster were established from Daejon in Korea and were examined in order to investigate the changes of cytotype or strain type by P-M system through 1∼15 generations. The results are as follows: 1. Using π_2 (strong P) strains and bw;st (true M) strains as standard strains, the mean sterility frequencies from Cross A were 20.8%∼34.6% for each generations and the mean sterility frequencies from Cross B were 0.0%∼0.3%. 2. Frequency of strain with P cytotype for each generation was analyzed to be 44.8%(G₁), 59.2%(G₂), 43.7%(G₄), 36.7%(G_7), 29.2%(G_10) and 36.7%(G_15). Therefore it was tend to be low as increased with generation number, but the differencies in percentage of GD sterility between each generation are non-significant statistically. 3. Among the isofemale lines, type conversions were observed. Q→M', M'→Q and M'→M changes have occured with frequency of 18.4%, 8.2% and 4.1%, respectively. The remaining lines (69.3%) were unchanged through several generations. 4. The results suggest that Drosophila melanogaster are appeared temporally as a certain strain type in natural population, but the type conversions were represented by interactions between P elements in each genome and cytoplasm for each generation.

정상교합자와 골격성 Ⅲ급 부정교합자의 저작운동형태의 비교

성기혁,성재현 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.5

정상교합자와 골격성 Ⅲ급 부정교합자의 저작운동형태를 비교연구하기위해서 30명의 정상교합자와 20명의 골격성Ⅲ급 부정교합자를 대상으로 츄잉검을 사용하고 BioPAK system을 이용하여 전두면상에서 저작운동을 기록, 분석하였다. 각 개체마다 대표하는 저작경로를 정하여 저작폭경, 개구거리, 개구각, 폐구각, 최대개구속도, 최대폐구속도를 알아보았다. 또 저작경로의 형태에 따라 특징적인 7가지 패턴으로 분류하여 다음의 결과를 얻었다. 1. 정상교합자군에 비해 골격성Ⅲ급 부정교합자군에서는 좀 더 다양하고 수직적인 저작양상을 나타내었다. 2. 저작폭경의 비교에서는 골격성Ⅲ급 부정교합자군이 정상교합자군에 비해 더 좁게 나타났다(P<0.01). 3. 개구거리에서는 골격성Ⅲ급 부정교합자군이 정상교합자군에 비해 더 작게 나타났으나 통계학적으로 유의성은 없었다(P>0.05). 4. 개구각과 폐구각에서는 골격성Ⅲ급 부정교합자군에서 정상교합자군보다 더욱 예각으로 나타났다(P<0.01). 5. 최대개구속도, 최대폐구속도에서는 정상교합자군에 비해 골격성Ⅲ급 부정교합자군에서 느리게 나타났으나 통계학적으로 유의성은 없었다(P>0.05). 6. 저작운동형태에 따른 분류에서 정상교합자군에서는 Type Ⅱ가 73.4%로 가장 많은 비율을 차지하였으나 골격성 Ⅲ급 부정교합자군에서는 Type Ⅲ가 35.0%, Type Ⅱ가 30.0%로 많은 비율을 차지하였다. 7. 저작운동형태에 따른 분류에서 골격성 Ⅲ급 부정교합자군에서는 Type Ⅳ(chopping type)가 25.0%로 정상교합자군 3.3%에 비해 많은 비율을 차지하였다. A comparative study was made on the chewing movements of normal occlusion and skeletal classⅢ malocclusion. Thirty normal occlusion subjects and twenty skeletal classⅢ malocclusion patients were given chewing gums for the study ; using BioPAK system, the chewing movement on the frontal plane was recorded and analyzed. With a typical chewing path chosen representing each subject, chewing width, opening distance, opening and closing angle, maximum opening and closing velocities were observed. Seven characteristic patterns were classified based on the types of chewing paths. The followings are the results: 1. Compared with the normal occlusion group, the skeletal classⅢ malocclusion group showed more varied and vertical chewing patterns. 2. In comparision of chewing widths, skeletal classⅢ malocclusion group showed narrower path than the normal occlusion group(P<0.01). 3. In opening distance, skeletal classⅢ malocclusion group appeared shorter than the normal occlusion group without statistical significance(P>0.05). 4. In opening and closing angles, skeletal classⅢ malocclusion group showed more acute angles than the normal occlusion group(P<0.01). 5. In maximum opening and closing velocities, skeletal classⅢ malocclusion group was slower than the normal occlusion group but with no statistical significance(P>0.05). 6. In the classification of chewing movement pattern, the normal occlusion group had TypeⅡ as the highest rate at 73.4%; in skeletal classⅢ malocclusion group, the highest rate was TypeⅢ at 35.0%, followed by TypeⅡ at 30.0%. 7. In the classification of chewing movement pattern, Type IV(chopping type) of skeletal classⅢ malocclusion group showed a higher rate with 25.0% over 3.3% of normal occlusion group.

韓國人 指紋型의 遺傳學的 分析

成耆昌,李起俊 성균관대학교 기초과학연구소 1985 論文集 Vol.36 No.2

The finger print pattern of the Korean population has been examined. The predominant finger print type of non-criminal population consisted of 49% Loop type, 45.5% Whorl type, 2.6% Simple arch and 2.5% Tented arch. Among criminal populations, the frequency of occurance of finger print types was found to be 52.2% Loop type, 40.9% Whorl type, 2.5% Tented arch, and 2.8% Simple arch respectively. In addition, criminal population contained 0.3% Accidental type, which was absent in non-criminal population. The total Ridge Number for the non-criminals was 151 for females and 143 for males, while in criminal population it was 127 for females and 138 for males. The atd angle for non-criminal population was 82.29° for males and 83.38° for females. The a-b ridge number was found to be 76.05 for males and 73.24 for females.

Drosophila quinaria Species Group의 遺傳的 近緣關係

成耆昌,金正洙,金大鎰,金彧,金溶聲 성균관대학교 기초과학연구소 1985 論文集 Vol.36 No.2

The genetic relatedness among the Korean Drosophila quinaria species group, including D. nigromaculata, D. unispina, D. brachynephrose, and D. angularis, has been examined by using horizontal starch gel electrophoresis. The results showed that none of the ten isozyme patterns examined for these four species was identical. The average genetic similarity among the four species was found to be 0.440. The similarity among three species. D. unispina, D. brachynephrose, and D. angularis was 0.466. The relatedness was found to be closest between D. nigromaculata and D. unispina, showing 0.640. D. nigromaculata and D. angularis showed relatedness of 0.258. The results suggested that these four species appear to be genetically related at the level of sibling species. The percent polymorphism in D. brachynephrose was found to be 76.9%, showing significant genetic variations.

영암과 심프슨의 종말론 비교 연구

성기호 聖潔大學校 聖潔神學硏究所 1996 聖潔神學硏究 Vol.1 No.-

기저세포암, 피부전이암과 유사한 조직소견을 보인 안검 외 피지선암 1예

김상태,노효진,서기석 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

Backgroud : Extraocular sebaceous carcinoma is a malignant tumor derived from the adnexal epithelium of sebaceous glands. A poorly differentiated sebaceous carcinoma shows variable histopathologic findings and mimics other primary tumor and cutaneous metastases mostly composed of clear cells. Case : Our patient consultation was requested for a 53 year?old female with solitary mild painful tumor on the scalp. The first histopathlogic impression of this case was basal cell carcinoma on the other hospital. After reevaluation, our diagnosis is not basal cell carcinoma but extraocular sebaceous carcinoma. Conclusion : A thorough exact recognition of characteristic histopathologic features of extraocular sebaceous carcinoma is necessary for making diagnosis, treatment plan and determining the prognosis.

Drosophila immigrans Sturtevant에 있어서 同所集團과 異所集團의 性的隔離

成耆昌,金容圭,金溶聲 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.2

한국 Drosophila immigrans 집단의 유전적 구조를 밝히는 연구의 일환으로 5개집단(설악, 대전, 광주, 부산, 제주)을 대상으로 pair-mating시켜 "dissection of sperm"방법을 이용하여 동소집단과 이소집단의 성적격리를 실험하였다. 본 실험의 결과는 다음과 같다. (1) 한국 D. immigrans 집단의 경우 동소집단의 성적격리도가 이소집단보다 높았으며 Ehrman & Parsons^17,18)과는 상반되는 결과를 보였다. (2) 지리적격리가 성적도태 요인이 되지 않는 것 같다. (3) 한국 D. immigrans 집단의 평균성적격리도는 지금까지 조사된 어느 집단보다도 낮았다. (4) 집단간의 성적격리도는 통계적으로 유의한 차를 보였다. (5) 한국 D. immigrans 집단의 성적격리는 "founder effect"로 설며하는 것이 타당하나, 환경여건 및 "habitat selection"에 의해 일어나는 현상도 결코 배제할 수 없을 것 같다. (6) isofemale 계통에 관한 계속적인 연구가 행하여지는 경우, 한국 D. immigrans 집단의 성적격리에 의한 진화문제에 좋은 자료가 될 것으로 기대한다. In order to clarify the genetic structure of Korean populations of Drosophila immigrans, the natural populations of D. immigrans were sampled at 5 localities (Mt. Sorak, Daejon, Kwangju, Pusan, Jeju isl.). By pair-mating and dissection of sperm, sexual isolation in sympatric and allopatric populations was analyzed. The results are as follows: 1. Sexual isolation of sympatric populations is higher than that of allopatric populations and it is opposed to the results of Ehrman and Parsons.^17,18) 2. The degree of isolation does not depend upon the geographic distance. 3. It was noted that the average isolation indices observed in Korean populations of D. immigrans were low as compared with those of several populations of D. immigrans by other workers. 4. Statistically significant sexual isolation occured between populations. 5. It is suggested that the maintenance of sexual isolation in Korean populations of D. immigrans be due to "founder effect" and cannot be excluded that it is due to environmental conditions and "habitat selection". 6. The detailed study of isofemale strains will give an idea of the potential for evolution of sexual isolation in Korean populations of D. immigrans.

目錄 電算化에 관한 硏究

成耆珠 同德女子大學校 1984 同大論叢 Vol.14 No.1

Computerizing of library system is the main subject in our library circles. There are two different methods in library computerization which one is Total System and the other is Piecemeal System. In general, Piecemeal System is being accepted by system librarians. And the Cataloguing System will be the first step in Piecemeal system. Because the Cataloguing system is the very method to making the Bibliographic Data Base. In this paper two kind of methods concerning the cataloguing system is being represented: 1. Program on Card Printing System 2. Program on Retrieval System. Through the method 1 the various kind of cataloguing cards will be printed out automatically and the retrieval of bibliographic information will be achieved by method 2. Comparing with the manual system, we realize the effectiveness of the computerized cataloguing system.

間接螢光抗體法 및 免疫黃金標識法을 이용한 肝吸蟲組織內 抗原性部位에 관한 硏究

成大林,金洙鎭,嚴基善,林漢鍾 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.3

Indirect fluorescent antibody test and immunogold labeling method were accomplished to observe the antigenic localization in the tissues of adult Clonorchis sinesis. Immunoglobulins (IgG) for the reaction were obtained from white rats and rabbits, at eight weeks after experimental infection with 50 and 500 metacercariae of C. sinensis, respectively. Frozen sectioned adult worm antigen (8μm) and FITC-conjugated goat anti-rat, rabbit IgG were used for indirect fluorescent antibody test. On the other hand, sectioned tissue antigen embedded in Lowcryl HM 20 medium and secondary antibody protein A gold complex (particle size:12 nm) were used for immunogold labeling method. In the results, fluorescence or gold particle were not observed on the tissue antigens of the worm when reacted with the noninfected control IgG. However, with the infected animal groups IgG, fluorescence or gold particles were observed on the interstitial matrix (body fluid) between the various organs, such as the tegumental cells, parenchyma, testes, receptaculum seminis. And the cecal epithelium including cecal contents and epithelium of excretory bladder also showed strong reaction. Therefore, antigenic materials which stimulate the IgG antibodies against the host were thought to be fluid substances and digestive enzymes or excretory materials which make up the interstitial matrix in the tissues of the worm.

韓國 노랑초파리의 염색체내 KP element의 分布에 관한 硏究

成耆昌 성균관대학교 기초과학연구소 1992 論文集 Vol.43 No.2

In order to clarify the behavior of KP element in korean population of D. melanogaster, isofemale lines(168) were estabilished at YJ island from September in 1991. (1) It was tested by P-M system for P factor activity and cytotype. Simultaneously, (2) Strain type for population were analysed. (3) After 15 generations, some selected lines tested P factor activity. And then, 5 lines analysed by in situ hybridization with biotin-labeled pπ 25.1 DNA probes(4.7kb and 0.7kb). The results were as follows. (1) The cytotype is widely distributed and P factor activity are very low (3%) in this population. (2) It was analysed that isofemale line was consist of M(0.6%), M'(41%), Q(56.5%) and no P strain. It was mainly consist of M' and Q strain like any other Korea population. (3) The copy number of P element was strong P(43), Q(27) and three M'(33.3) strain per genome on larval polytene chromosome. PstI porbe (0.7 kb) was hybridized only autonomous P element. Therefore, supposed that many KP elements contained on chromosome of YJ island population.