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      • KCI등재

        Cord Dorsum Potentials Evoked by Electroacupuncture Applied to the Hind Limbs of Rats

        Salvador Quiroz-González,Bertha Segura-Alegría,José Carlos Guadarrama-Olmos,Ismael Jiménez-Estrada 사단법인약침학회 2014 Journal of Acupuncture & Meridian Studies Vol.7 No.1

        The longitudinal distribution of the cord dorsum potentials (CDPs) produced by electro- acupuncture (EA) stimulation at acupuncture points (APs) located on the hind limbs of rats was analyzed in this study. Single electrical pulses (0.05 ms, 1 Hz) applied to the bladder (BL) and the gallbladder (GB) APs produced CDPs on several spinal segments and were composed of the following four components: an afferent volley, two negative components (N₁and N₂), and one positive component (P wave). The larger evoked CDPs differed in their rostrocaudal distributions depending on the stimulated AP site, with those evoked by GB32e33 (at L3) and GB36e37 (at L4) being more caudal than those generated by BL58e59 (at L5) and BL37e38 (at L6). The CDPs produced by stimulating nonacupoints (NAPs) showed similar components and rostrocaudal distributions that were smaller in amplitude than those evoked by stimulating APs. The CDPs produced by stimulating NAPs located on a meridian acupuncture area were similar in amplitude and longitudinal distribution to those produced by stimulating APs. Our results suggest that the specificity of EA stimulation for CDPs responses is mainly related to an activa-tion of meridian pathways associated with peripheral nerve routes rather than to a restricted point specificity of APs.

      • KCI등재

        Changes in Heart Rate Variability in Patients with Spleen-Qi Deficiency Syndrome

        Agnese Olivera-Toro,Rubén Fossion,Lei Li,Rosa E. López-Gómez,Emma López-Espinosa,Ismael Jiménez-Estrada,Salvador Quiroz-González 사단법인약침학회 2019 Journal of Acupuncture & Meridian Studies Vol.12 No.4

        Many functional diseases are related to dysautonomia, and heart rate variability has been used to assess dysautonomia. However, heart rate variability has not been studied in Spleen-Qi deficiency syndrome (SQDS). Healthy volunteers (n Z 37) and patients with SQDS (n Z 67), recruited from the Clinic of the State University of Ecatepec Valley were included in the study. Outcome measures were average heart rate, standard deviation of the normal-to-normal heartbeat intervals, low frequency (LF), high frequency (HF) power, and the LF/HF ratio. Also, intestinal peristalsis, gastrointestinal symptoms (GSs), fatigue, and level of attention were measured. Standard deviation of the normal-to-normal heartbeat intervals (17 Æ 2.3%) and HF (14 Æ 3.1%) were lower in SQDS patients (17 Æ 1.3%) than in healthy volunteers. SQDS patients had higher heart rate, LF power, LF/HF ratio, and fatigue scores (9.6 Æ 1.12%, 16 Æ 2.1%, 22 Æ 3.8%, and 21 Æ 4.1%). The fatigue correlated positively with the LF/HF ratio and negatively with HF power. The SQDS group had lower concentration performance (16.2 Æ 1.9%) in the d2 test. The intestinal peristalsis showed a reduction (15 Æ 1.3%) as compared with control. GS score and peristalsis correlated negatively with HF. Our results suggest that the pathology of SDQS could be associated with a low vagal tone which causes a decrease in peristalsis, increased fatigue, reduced attention, and appearance of GSs.

      • KCI등재

        Heart Rate Variability and Psychometric Analysis in Patients with Hyperactive Heart Fire Syndrome

        Oliverio Medina Martínez,Ruben Fossion,Yolanda García Piceno,Rosa E. Lopez-Gomez,Emma López-Espinosa,Ismael Jiménez-Estrada,Salvador Quiroz-González 사단법인약침학회 2021 Journal of Acupuncture & Meridian Studies Vol.14 No.4

        Background: Hyperactive heart fire syndrome is characterized by anxiety, insomnia, dream-disturbed sleep, tongue ulcers, heat in the hands, and palpitations. However, syndrome differentiation is often subjective due to a lack of objective, quantifiable variables. Objectives: To identify changes in heart rate variability (HRV) and psychometric analysis in patients with hyperactive heart fire syndrome. Methods: Healthy controls (n = 33) were compared to patients with hyperactive heart fire syndrome (n = 48) from the Integrative University Clinic of the State University of Ecatepec Valley (CIU-UNEVE). Physiological outcome measures included heart rate (HR), the standard deviation of the normal-to-normal heartbeat intervals (SDNN), low (LF) and high frequency (HF) power, and the LF/HF ratio. Psychometric outcome measures included the Athens Insomnia Scale (AIS) and the Hamilton Anxiety Rating Scale (HARS). Results: Compared to controls, hyperactive heart fire patients had higher HR (9.6 ± 2.62%), LF (22 ± 4.21%) and LF/HF ratio (23 ± 3.14%), and lower SDNN (21 ± 2.33%) and HF (18 ± 4.61%). Patients showed increased anxiety, both with somatic (33 ± 11.2%) and psychic symptoms (39 ± 10.5%) with more difficulty falling asleep (47 ± 9.9%) and diurnal impact of sleep (31 ± 9.6%). Conclusion: Hyperactive heart fire patients may have a sympathovagal imbalance due to a reduced parasympathetic tone and/or adominant sympathetic tone, which may be at the origin of the observed symptoms of insomnia and anxiety.

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