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Sperm DNA Fragmentation: A Critical Assessment of Clinical Practice Guidelines
Agarwal Ashok,Farkouh Ala'a,Parekh Neel,Zini Armand,Arafa Mohamed,Kandil Hussein,Tadros Nick,Busetto Gian Maria,Ambar Rafael,Parekattil Sijo,Boitrelle Florence,Sallam Hassan N.,Jindal Sunil,Ko Edmund 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.1
Sperm DNA fragmentation (SDF) is implicated in male infertility and adverse reproductive outcomes. With the publication of many studies regarding the etiologies and contributors to SDF, as well as the effects of SDF, guidelines are necessary to aid clinicians in the application of SDF for male fertility evaluation. Two recent clinical practice guidelines were published by Agarwal et al and Esteves et al. In this article, we have evaluated and compared both guidelines. We have found fairly similar recommendations between the two guidelines and have also highlighted the differences between them. Finally, we have summarized and combined the best practice recommendations from both guidelines.