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        A Comparison of the Compression-Recovery Behavior of Conventional and Double-Base Persian Rugs: Compression Behavior

        Milad Sadeghi-Sadeghabad,Aliasghar Alamdar-Yazdi,Mohammad R. Fazel,Hasan Mashroteh 한국섬유공학회 2020 Fibers and polymers Vol.21 No.6

        One of the most important behaviors of a rug is its compression-recovery effect. This paper compares thecompression properties of a conventional and a new Persian rug. In the new rug, some free spaces are created in the base partwithin the warp sheets. To do the comparison experiments, five rug samples were produced: A conventional Persian rug asthe comparison criterion plus four new types of rugs named Double-base Persian (DBP) rugs. At first, a theoretical analysisof the compression process in both conventional and new rugs is presented for further comparisons and validation. Then,using the tensile tester compression-recovery curves of the rug samples were obtained and experimentally investigated. Results of the theoretical analysis showed that in conventional rug, diameter, length and young’s modulus of pile yarn andapplied load are effective parameters, and in DBP rugs, in addition to those parameters, the gap size and warp yarn diameterare effective parameters on the compression deformation. Also, the experimental results showed that when a gap isintroduced in the rug base, the comfort and compressibility were significantly improved. Besides, increasing the distancebetween the two warp sheets effectively improves the comfort and compressibility of the DBP rugs.

      • Systematic Review of Available Guidelines on Fertility Preservation of Young Patients with Breast Cancer

        Haddadi, Mahnaz,Muhammadnejad, Samad,Sadeghi-Fazel, Fariba,Zandieh, Zahra,Rahimi, Gohar,Sadighi, Sanambar,Akbari, Parya,Mohagheghi, Mohammad-Ali,Mosavi-Jarrahi, Alireza,Amanpour, Saeid Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

        Background: Since the survival rate of breast cancer patients has improved, harmful effects of new treatment modalities on fertility of the young breast cancer patients has become a focus of attention. This study aimed to systematically review and critically appraise all available guidelines for fertility preservation in young breast cancer patients. Materials and Methods: Major citation databases were searched for treatment guidelines. Experts from relevant disciplines appraised the available guidelines. The AGREE II Instrument that includes 23 criteria in seven domains (scope and purpose of the guidelines, stakeholder involvement, rigor of development, clarity, applicability, editorial independence, and overall quality) was used to apprise and score the guidelines. Results: The search strategy retrieved 2,606 citations; 72 were considered for full-text screening and seven guidelines were included in the study. There was variability in the scores assigned to different domains among the guidelines. ASCO (2013), with an overall score of 68.0%, had the highest score, and St Gallen, with an overall score of 24.7%, had the lowest scores among the guidelines. Conclusions: With the promising survival rate among breast cancer patients, more attention should be given to include specific fertility preservation recommendations for young breast cancer patients.

      • Correlation of Microvessel Density with Nuclear Pleomorphism, Mitotic Count and Vascular Invasion in Breast and Prostate Cancers at Preclinical and Clinical Levels

        Muhammadnejad, Samad,Muhammadnejad, Ahad,Haddadi, Mahnaz,Oghabian, Mohammad-Ali,Mohagheghi, Mohammad-Ali,Tirgari, Farrokh,Sadeghi-Fazel, Fariba,Amanpour, Saeid Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        Background: Tumor angiogenesis correlates with recurrence and appears to be a prognostic factor for both breast and prostate cancers. In the present study, we aimed to investigate the correlation of microvessel density (MVD), a measure of angiogenesis, with nuclear pleomorphism, mitotic count, and vascular invasion in breast and prostate cancers at preclinical and clinical levels. Methods: Samples from xenograft tumors of luminal B breast cancer and prostate adenocarcinoma, established by BT-474 and PC-3 cell lines, respectively, and commensurate human paraffin-embedded blocks were obtained. To determine MVD, specimens were immunostained for CD-34. Nuclear pleomorphism, mitotic count, and vascular invasion were determined using hematoxylin and eosin (H&E)-stained slides. Results: MVD showed significant correlations with nuclear pleomorphism (r=0.68, P=0.03) and vascular invasion (r=0.77, P=0.009) in breast cancer. In prostate cancer, MVD was significantly correlated with nuclear pleomorphism (r=0.75, P=0.013) and mitotic count (r=0.75, P=0.012). In the breast cancer xenograft model, a significant correlation was observed between MVD and vascular invasion (r=0.87, P=0.011). In the prostate cancer xenograft model, MVD was significantly correlated with all three parameters (nuclear pleomorphism, r=0.95, P=0.001; mitotic count, r=0.91, P=0.001; and vascular invasion, r=0.79, P=0.017; respectively). Conclusions: Our results demonstrate that MVD is correlated with nuclear pleomorphism, mitotic count, and vascular invasion at both preclinical and clinical levels. This study therefore supports the predictive value of MVD in breast and prostate cancers.

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