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Flavonoid Glycosides from Prunus armeniaca and the Antibacterial Activity of a Crude Extract
Fahima Rashid,Rehana Ahmed,Azhar Mahmood,Zaheer Ahmad,Nazia Bibi,Shahana Urooj Kazmi 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.8
Investigations on the chemical constituents of the fruits of Prunus armeniaca have led to the isolation of two new flavonoid glycosides, 4',5,7-trihydroxy flavone-7-O-[β-D-mannopyranosyl (1'''→2'')]-β-D-allopyranoside (1) and 3,4',5,7-tetrahydroxy-3',5'-di-methoxy flavone 3-O-[α-Lrhamnopyranosyl (1'''→6'')]-β-D-galactopyranoside (2), from the butanolic fraction of the fruits. The butanolic extract exhibited antibacterial activity against both Gram positive and Gram negative bacteria. The structures of these compounds were elucidated through spectral studies, including 2D-NMR (COSY, NOESY, J-resolved), HMQC and HMBC experiments.
Purunusides A-C, α-Glucosidase Inhibitory Homoisoflavone Glucosides from Prunus domestica
Shaheen Kosar,Itrat Fatima,Azhar Mahmood,Rehana Ahmed,Abdul Malik,Muhammad Iqbal Chouhdary,Sumaira Talib 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.12
Purunusides A-C (1-3), new homoisoflavone glucosides together with the known compounds β-sitosterol (4) and 6,7-methylenedioxy-8-methoxycoumarin (5) have been isolated from nbutanol and ethyl acetate soluble fractions of Prunus domestica. Their structures were assigned on the basis of spectral studies. The compounds 1-3 showed potent inhibitory activity against the enzyme α-glucosidase.
Flavonoid Glycosides from Prunus armeniaca and the Antibacterial Activity of a Crude Extract
Rashid, Fahima,Mahmood, Azhar,Ahmad, Zaheer,Bibi, Nazia,Kazmi, Shahana Urooj,Ahmed, Rehana 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.8
Investigations on the chemical constituents of the fruits of Prunus armeniaca have led to the isolation of two new flavonoid glycosides, 4',5,7-trihydroxy $flavone-7-O-[{\beta}-D-mannopyranosyl(1'{\rightarrow}2')]-{\beta}-D-allopyranoside$ (1) and 3,4',5,7-tetrahydroxy-3',5'-di-methoxy flavone $3-O-[{\alpha}-L-rhamnopyranosyl(1'{\rightarrow}6')]-{\beta}-D-galactopyranoside$ (2), from the butanolic fraction of the fruits. The butanolic extract exhibited antibacterial activity against both Gram positive and Gram negative bacteria. The structures of these compounds were elucidated through spectral studies, including 2D-NMR (COSY, NOESY, J-resolved), HMQC and HMBC experiments.