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Song, Seulki,Hill, Rebecca,Choi, Kyoungwon,Wojciechowski, Konrad,Barlow, Stephen,Leisen, Johannes,Snaith, Henry J.,Marder, Seth R.,Park, Taiho unknown 2018 Nano energy Vol.49 No.-
<P><B>Abstract</B></P> <P>We report flexible planar perovskite solar cells with robust electron-transport layers (ETLs) processed at low temperature. A poly(allylamine) (PAA; 0.08 wt%) solution was deposited on a C<SUB>60</SUB> layer and heated at 150 °C for 60 s, resulting in the formation of an insoluble robust C<SUB>60</SUB>–PAA electron-transport layer (ETL) on the flexible substrate. The flexible planar perovskite solar cell with the C<SUB>60</SUB>–PAA ETL exhibited excellent properties with 83% efficiency retention (η = 15.2% without hysteresis) after 600 cycles of bending. This performance is superior to that of the flexible device with a C<SUB>60</SUB> ETL fabricated without the use of PAA (65% efficiency retention; η = 9.8% with some hysteresis).</P> <P><B>Highlights</B></P> <P> <UL> <LI> A modified fullerene-based electron transport layer is proposed for stable flexible perovskite device. </LI> <LI> A poly(allylamine) (PAA; 0.08 wt%) solution was deposited on a C<SUB>60</SUB> layer to form a C<SUB>60</SUB>-PAA. </LI> <LI> C<SUB>60</SUB>–PAA electron-transport layer (ETL) is insoluble in perovskite precursor solution. </LI> <LI> Flexible planar perovskite solar cell with the C<SUB>60</SUB>–PAA ETL exhibited excellent properties with 83% efficiency retention. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
The link of unintentional weight loss to cardiac event-free survival in patients with heart failure.
Song, Eun Kyeung,Lee, Yongjik,Moser, Debra K,Dekker, Rebecca L,Kang, Seok-Min,Lennie, Terry A ASPEN PUBLISHERS INC 2014 JOURNAL OF CARDIOVASCULAR NURSING Vol.29 No.5
<P>Patients with heart failure (HF) commonly have unintentional weight loss, depressive symptoms, and elevated levels of high-sensitivity C-reactive protein (hsCRP). Each of these variables has been independently associated with shorter cardiac event-free survival. However, little data exist on the relationships of unintentional weight loss, hsCRP level, and depressive symptoms to cardiac event-free survival.</P>
miR-218 and miR-129 regulate breast cancer progression by targeting Lamins
Setijono, Stephanie Rebecca,Park, Mikyung,Kim, Goeun,Kim, Yongjo,Cho, Kae Won,Song, Su Jung Elsevier 2018 Biochemical and biophysical research communication Vol.496 No.3
<P><B>Abstract</B></P> <P>Breast cancer is the most frequently diagnosed life-threatening cancer in women. Triple-negative breast cancer (TNBC) has an aggressive clinical behavior, but the treatment of TNBC remains challenging. MicroRNAs (miRNAs) have emerged as a potential target for the diagnosis, therapy and prognosis of breast cancer. However, the precise role of miRNAs and their targets in breast cancer remain to be elucidated. Here we show that miR-218 is downregulated and miR-129 is upregulated in TNBC samples and their expressions confer prognosis to patients. Gain-of-function and loss-of-function analysis reveals that miR-218 has a tumor suppressive activity, while miR-129 acts as an oncomir in breast cancer. Notably, miR-218 and miR-129 directly target Lamin B1 and Lamin A, respectively, which are also found to be deregulated in human breast tumors. Finally, we demonstrate Lamins as the major factors in reliable miR-218 and miR-129 functions for breast cancer progression. Our findings uncover a new miRNA-mediated regulatory network for different Lamins and provide a potential therapeutic target for breast cancer.</P> <P><B>Highlights</B></P> <P> <UL> <LI> miR-218 is downregulated and miR-129 is upregulated in breast cancer. </LI> <LI> miR-218 inhibits and miR-129 promotes breast cancer proliferation and migration. </LI> <LI> Lamins are identified as a novel target of miR-218 and miR-129. </LI> <LI> miR-218 and miR-129 play their biological functions by Lamins in breast cancer. </LI> </UL> </P>
Intranasal drug delivery in pediatric emergency departments: brief review and future outlook
Christopher Hugh McClean,Mohammad Hussein Alsabri,Sania Tahir,Rebecca Song,Christopher Chin 대한소아응급의학회 2023 대한소아응급의학회지 Vol.10 No.4
This review aims to provide an overview and update of current literature on the use of intranasal (IN) drug delivery in pediatric emergency medicine (PEM), in terms of the anatomy, physiology, pharmacokinetics, limitations, drug delivery methods, necessary training, safety, contraindications, effectiveness, current indications and trends, and implications for clinical practice and future developments in IN drug administration. We evaluate how IN medication use in PEM has recently evolved, what recent research has revealed about the utility of IN drug delivery in PEM, and what the future of IN drug delivery might look like.