http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Utility of Serum YKL-40 as a Tumor-Specific Marker of Hepatobiliary Malignancies
( Ju Dong Yang ),( Eugene Kim ),( Rachel A. Pedersen ),( W. Ray Kim ),( Surakit Pungpapong ),( Lewis R. Roberts ) 대한소화기기능성질환·운동학회 2010 Gut and Liver Vol.4 No.4
Background/Aims: Serum YKL-40 has been linked to several human cancers. We investigated the potential role of serum YKL-40 as a marker of hepatobiliary malignancies. Methods: Archived serum samples of patients undergoing liver transplantation evaluation at the Mayo Clinic Rochester were used to measure YKL-40 levels. Patients were divided into three groups: hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and end-stage liver disease (ESLD) without malignancies. The Model for ESLD (MELD) score was used to quantify the severity of liver disease. Results: The median serum YKL-40 level was highest in the ESLD group at 296 ng/mL, compared to 259 ng/mL in the HCC group and 80 ng/mL in the CCA group (p<0.01). There was a significant correlation between the MELD score and serum YKL-40 level (r=0.50, p<0.01). In a multivariate analysis, there was no significant difference in serum YKL-40 level between ESLD and HCC. CCA was associated with lower YKL-40 levels, a finding that was attributable to a lower prevalence of cirrhosis. Conclusions: The serum YKL-40 level has little utility as a cross-sectional screening tool for hepatobiliary malignancies, namely HCC and CCA. The role of YKL-40 as a surveillance marker in the follow-up of individual patients remains to be determined. (Gut Liver 2010;4:537-542)
An Empirical Analysis of ISO 9004:2000 Maturity in ISO 9001 Certified SMEs
Lewis, W.G.,Pun, K.F.,Lalla, T.R.M. The Korean Society for Quality Management 2005 The Asian Journal on Quality Vol.6 No.3
This paper empirically determines the extent to which ISO 9001 certified small and medium-sized enterprises (SMEs) were able to attain the eight quality management principles on which the ISO 9004:2000 Standard is based. It employs the Analytic Hierarchy Process approach in determining the percent weightings of these principles and the self-assessment questions which form part of the ISO 9004:2000 Standards. Of particular interest is a weakness of these enterprises in formulating policies addressing the needs and expectations of shareholders and the society in terms of the community and the public affected by the organisations or its products. This paper makes a contribution to the body of knowledge in the field of quality management in Trinidad and Tobago where such work is limited. It adds value by empirically measuring TQM implementation through determining the extent to which its criteria are implemented in ISO 9001 certified SMEs.
Lewis, W.G.,Pun, K.F.,Lalla, T.R.M. The Korean Society for Quality Management 2004 The Asian Journal on Quality Vol.5 No.2
Many researchers and practitioners have acknowledged the need to investigate the relationships amongst various criteria of implementing total quality management (TQM) in small and medium-sized manufacturing enterprises (SMMEs). There is a need to have practical research methodologies that take cognisance of the peculiarities of SMMEs and impact on their quality management practices in developing countries. This paper presents the theoretical foundation of a proposed Generative Research Methodology and configures the specification of a TQM implementation framework in SMMEs. The methodology combines rigorous research approaches, builds theory based on the dynamics of the environment and the firms' characteristics and incorporates various TQM criteria into the design of the framework. It synchronises inductive and deductive research methods in three phases and uses various means to acquire empirical evidence and examine the dependent and independent variables of TQM implementation. It is anticipated that the methodology could help SMMEs to develop, analyse and evaluate the framework for attaining quality performance goals.
Measuring Top Management Commitment in SMEs: A Self-Assessment Scale
Lewis, Winston G.,Pun, Kit F.,Lalla, Terrence R.M. The Korean Society for Quality Management 2007 The Asian Journal on Quality Vol.8 No.3
This paper describes the development of a scale for measuring top management commitment towards continual quality performance improvement in small and medium-sized enterprises (SMEs). A set of self-assessment questions of the ISO 9004: 2000 Standard was used to assess the adoption status of quality management practices. This paper investigates the inter-item reliability and the content validity of the Quality Management Principles Scale (QMPS) in an integrated improvement process in SMEs. An empirical study was conducted to acquire senior management views on the use of the QMPS in manufacturing sectors in Trinidad and Tobago. Based on 328 responses from 110 SMEs, statistical software packages were used to analyse the empirical data and determine the reliability and validity of the QMPS. The paper contributes to develop a self-assessment scale that can be used to measure top management commitment. It is anticipated that the findings would provide practical insights for evaluating the levels of maturity on performance improvement in SMEs.
Lewis R. Rambo 한국기독교교육정보학회 2011 Journal of Christian education information tech Vol.0 No.19
This paper seeks to discern themes and patterns in our search to make sense of the vicissitudes of current academic disciplines (especially religious education and pastoral psychology) through explorations of the resources of film, culture, and religion/spirituality. These resources provide cutting edge concepts, methods, and theories that can expand the horizons of religious education and pastoral psychology.