http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Plate, Markus,Li, Ting,Wang, Yu,Mo, Xiaoning,Zhang, Yingmei,Ma, Dalong,Han, Wenling Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.29 No.4
Human CMTM is a novel gene family consisting of CKLF and CMTM1-8. CMTM4 is the most conserved gene and has three RNA splicing forms designated as CMTM4-v1, -v2 and -v3, but in many types of tissue and cell lines, only CMTM4-v1 and -v2 could be detected. CMTM4-v2 is the full length cDNA product, which has been highly conserved during e volution. CMTM4-v1 and -v2 a re broadly expressed in normal types of tissue. They are distributed on the cell membrane and across the cytoplasm in a speckled pattern. Overexpression of CMTM4-v1 and -v2 can inhibit HeLa cell growth via G2/M phase accumulation without inducing apoptosis. Therefore, CMTM4 might be an important gene involved in cell growth and cell cycle regulation.
Markus Plate,Ting Li,Yu Wang,Xiaoning Mo,Yingmei Zhang,Dalong Ma,Wenling Han 한국분자세포생물학회 2010 Molecules and cells Vol.29 No.4
Human CMTM is a novel gene family consisting of CKLF and CMTM1-8. CMTM4 is the most conserved gene and has three RNA splicing forms designated as CMTM4-v1, -v2 and -v3, but in many types of tissue and cell lines, only CMTM4-v1 and -v2 could be detected. CMTM4-v2 is the full length cDNA product, which has been highly conserved during evolution. CMTM4-v1 and -v2 are broadly ex-pressed in normal types of tissue. They are distributed on the cell membrane and across the cytoplasm in a speckled pattern. Overexpression of CMTM4-v1 and -v2 can inhibit HeLa cell growth via G2/M phase accumulation without inducing apoptosis. Therefore, CMTM4 might be an impor-tant gene involved in cell growth and cell cycle regulation.
( Johannes F. Plate ),( John S. Shields ),( Maxwell K. Langfitt ),( Michael P. Bolognesi ),( Jason E. Lang ),( Thorsten M. Seyler ) 대한고관절학회 2017 Hip and Pelvis Vol.29 No.4
Purpose: The Paprosky classification system of acetabular defects is complex and its reliability has been questioned. The purpose of this study was to evaluate the effectiveness of different radiologic imaging modalities in classifying acetabular defects in revision total hip arthroplasty (THA) and their value of at different levels of training. Materials and Methods: Bone defects in 8 revision THAs were classified by 2 fellowship-trained adult reconstruction surgeons. A timed presentation with representative images for each case (X-ray, two-dimensional computed tomography [CT] and three-dimensional [3D] reconstructions) was shown to 35 residents from the first postgraduate year of training year of training (PGY-1 to PGY-5), 2 adult reconstruction fellows and 2 attending orthopaedic surgeons. The Paprosky classification of bone defects was recorded. The influence of image modality and level of training on classification were analyzed using chi-square analysis (alpha=0.05). Results: Overall correct classification was 30%. The level of training had no influence on correct classification (P=0.531). Using X-ray led to 37% correctly identified defects, CT scans to 33% and 3D reconstructions to 20% of correct answers (P<0.001). There was no difference in correct classification based defect type (P<0.001). Regardless of level of training or imaging, 64% of observers recognized type 1 defects, compared to only 16% correct recognition of type 3B defects. Conclusion: Using plain X-rays led to an increased number of correct classification, while regular CT scan and 3D CT reconstructions did not improve accuracy. The classification system of acetabular defects can be used for treatment decisions; however, advanced imaging may not improve its utilization.
( He Nan Li ),( Xiao Huan Guo ),( Lu Ning Shao ),( Markus Plate ),( Xiao Ning Mo ),( Yu Wang ),( Wen Ling Han ) 한국생화학분자생물학회 (구 한국생화학회) 2010 BMB Reports Vol.43 No.3
The CKLF-like MARVEL transmembrane domain-containing family (CMTM) is a novel family of proteins linking classical chemokines and the transmembrane 4 superfamily (TM4SF). Our earlier studies indicated several CMTM members (such as CKLF1 and CMTM2) have a secreted form. This is the first report of the secreted form of CMTM5-v1, the major RNA splicing form of CMTM5, which is produced as small vesicles (<100 nm diameter) and floats at a peak density of 1.19 g/ml on continuous sucrose gradients. CMTM5-v1 has no obvious co-localization with CD63 or Golgi complex. In addition, brefeldin A but not wortmannin can inhibit the secretion of CMTM5-v1. Our results suggest that CMTM5-v1 might be secreted via a different vesicle-mediated secretory pathway, which will be helpful for the studies of vesicle-mediated secretion and MARVEL domain-containing proteins. [BMB reports 2010; 43(3): 182-187]
Status of the 25 T, 100 mm Bore HTS Solenoid for an Axion Dark Matter Search Experiment
Gupta, Ramesh,Anerella, Michael,Cozzolino, John,Joshi, Piyush,Joshi, Shresht,Plate, Stephen,Sampson, William,Song, Honghai,Wanderer, Peter,Chung, Woohyun,Kim, Jingeun,Ko, Byeong Rok,Youn, Sung Woo,Sem Institute of Electrical and Electronics Engineers 2019 IEEE transactions on applied superconductivity Vol.29 No.5
<P>This paper presents the design and test results of the pancake coils for the 25 T, 100 mm bore solenoid that Brookhaven National Laboratory (BNL) is building for the Institute for Basic Science (IBS) in Korea for an Axion dark matter search. The design is based on second-generation (2G) high-temperature superconducting (HTS) tape with no-insulation winding. The major challenges in the high-field, large aperture solenoid are the large stresses and the quench protection. Moreover, the design should be robust for reliable operation in a user facility environment. The paper will also present the construction and test results of two ∼100 mm bore double pancake coils creating a peak field of up to ∼17 T and similar hoop stresses as will be in the 25 T solenoid. The coils were subject to several severe tests, including the simulations of large defects and extended quench studies at ∼4 K. The most striking part of these studies was the demonstration of how fast (a few hundred milliseconds) these coils can turn from the superconducting state to the normal state (quench or thermal runaway). This removes the past concerns of protecting high-field HTS coils because of the low quench propagation velocities.</P>