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A Cyclohexenone Derivative from Diaporthaceous Fungus PSU-H2
Ubonta Sommart,Yaowapa Sukpondma,Souwalak Phongpaichit,Nongporn Hutadilok Towatana,Potchanapond Graidist,Zuboidah Hajiwangoh,Jariya Sakayaroj,Vatcharin Rukachaisirikul 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.9
One new cyclohexenone derivative (1) was isolated from Diaporthaceous fungus PSU-H2 together with six known compounds, dothiorelone A (2), dothiorelone C (3), 2,3-dihydromycoepoxydiene (4), (+)-mycoepoxydiene (5), deacetylmycoepoxydiene (6) and tyrosol (7). The structures were elucidated by spectroscopic methods. Their cytotoxic activity against human breast cancer cell line, MCF-7, was evaluated.
Vatcharin Rukachaisirikul,Nanthaphong Khamthong,Yaowapa Sukpondma,Souwalak Phongpaichit,Nongporn Hutadilok-Towatana,Potchanapond Graidist,Jariya Sakayaroj,Kanyawim Kirtikara 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.3
Nigrosporanenes A (1) and B (2), two new cylohexene derivatives, and tyrosol (3) were isolated from the sea fan-derived fungus Nigrospora sp. PSU-F11, whereas five known compounds: 4-hydroxybenzoic acid (4), aplysiopsene D (5), 3-isochromanone (6), (-)-drimenin (7) and diketopiperazine derivative (8), were obtained from the fungus Nigrospora sp. PSU-F12. Their structures were established by spectroscopic evidence. We also tested their cytotoxic (on African green monkey kidney fibroblast and breast cancer cells), antioxidant (in the DPPH assay), and antibacterial (against the standard Staphylococcus aureus ATCC 25923 and methicillinresistant S. aureus) activities.