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RISS 인기검색어
- 검색키워드
- 저자 : Ningning Ji (검색결과 5 건)
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Ningning Ji,Honghong Lou,Xinyan Gong,Ting Fu,Shimao Ni 대한심장학회 2018 Korean Circulation Journal Vol.48 No.10
Background and Objectives Appropriate inflammatory response is necessary for cardiac repairing after acute myocardial infarction (MI). Three-Bromo-4,5-dihydroxybenzaldehyde (BDB) is a potent antioxidant and natural bromophenol compound derived from red algae. Although BDB has been shown to have an anti-inflammatory effect, it remains unclear whether BDB affects cardiac remolding after MI. The aim of this study was to investigate the potential role of BDB on cardiac function recovery after MI in mice. Methods Mice were intraperitoneally injected with BDB (100 mg/kg) or vehicle control respectively 1 hour before MI and then treated every other day. Cardiac function was monitored by transthoracic echocardiography at day 7 after MI. The survival of mice was observed for 2 weeks and hematoxylin and eosin (H&E) staining was used to determine the infarct size. Macrophages infiltration was examined by immunofluorescence staining. Enzyme-linked immunosorbent assay (ELISA) was used to test the production of cytokines associated with macrophages. The phosphorylation status of nuclear factor (NF)-κB was determined by western blot. Results BDB administration dramatically improved cardiac function recovery, and decreased mortality and infarcted size after MI. Treatment with BDB reduced CD68+ macrophages, M1 and M2 macrophages infiltration post-MI, and suppressed the secretion of pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, monocyte chemoattractant protein (MCP)-1, and IL-6 in the injured hearts. Furthermore, BDB inhibited the phosphorylation of NF-κB in the infarcted hearts. Conclusions These data demonstrate, for the first time, that BDB treatment facilitated cardiac healing by suppressing pro-inflammatory cytokine secretion, and indicate that BDB may serve as a therapeutic agent for acute MI.
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Yiqi Liu,Qichao Chen,Ningning Li,Bing Xie,Jianze Wang,Yanchao Ji 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.1
In this study, we first briefly introduce the effect of circulating current control on the modulation signal of a modular multilevel converter (MMC). The maximum modulation index is also theoretically derived. According to the optimal modulation index analysis and the model in the continuous domain, different DC-side output impedance equivalent models of MMC with/without compensating component are derived. The DC-side impedance of MMC inverter station can be regarded as a series xR + yL + zC branch in both cases. The compensating component of the maximum modulation index is also related to the DC equivalent impedance with circulating current control. The frequency characteristic of impedance for MMC, which is observed from its DC side, is analyzed. Finally, this study investigates the prediction of the DC voltage ripple transfer between two-terminal MMC high-voltage direct current systems under unbalanced conditions. The rationality and accuracy of the impedance model are verified through MATLAB/Simulink simulations and experimental results.
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Yiqi Liu,Wenlong Song,Ningning Li,Linquan Bai,Yanchao Ji 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.6
This paper discusses the elimination of DC voltage deviation and the enhancement of load current sharing accuracy in multi-terminal high voltage direct current (MT-HVDC) systems. In order to minimize the power line losses in different parallel network topologies and to insure the stable operation of systems, a decentralized control method based on a modified droop control is presented in this paper. Averaging the DC output voltage and averaging the output current of two neighboring converters are employed to reduce the congestion of the communication network in a control system, and the decentralized control method is implemented. By minimizing the power loss of the cable, the optimal load current sharing proportion is derived in order to achieve rational current sharing among different converters. The validity of the proposed method using a low bandwidth communication (LBC) network for different topologies is verified. The influence of the parameters of the power cable on the control system stability is analyzed in detail. Finally, transient response simulations and experiments are performed to demonstrate the feasibility of the proposed control strategy for a MT-HVDC system.
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Liu, Yiqi,Song, Wenlong,Li, Ningning,Bai, Linquan,Ji, Yanchao The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.6
This paper discusses the elimination of DC voltage deviation and the enhancement of load current sharing accuracy in multi-terminal high voltage direct current (MT-HVDC) systems. In order to minimize the power line losses in different parallel network topologies and to insure the stable operation of systems, a decentralized control method based on a modified droop control is presented in this paper. Averaging the DC output voltage and averaging the output current of two neighboring converters are employed to reduce the congestion of the communication network in a control system, and the decentralized control method is implemented. By minimizing the power loss of the cable, the optimal load current sharing proportion is derived in order to achieve rational current sharing among different converters. The validity of the proposed method using a low bandwidth communication (LBC) network for different topologies is verified. The influence of the parameters of the power cable on the control system stability is analyzed in detail. Finally, transient response simulations and experiments are performed to demonstrate the feasibility of the proposed control strategy for a MT-HVDC system.
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Liu, Yiqi,Chen, Qichao,Li, Ningning,Xie, Bing,Wang, Jianze,Ji, Yanchao The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.1
In this study, we first briefly introduce the effect of circulating current control on the modulation signal of a modular multilevel converter (MMC). The maximum modulation index is also theoretically derived. According to the optimal modulation index analysis and the model in the continuous domain, different DC-side output impedance equivalent models of MMC with/without compensating component are derived. The DC-side impedance of MMC inverter station can be regarded as a series xR + yL + zC branch in both cases. The compensating component of the maximum modulation index is also related to the DC equivalent impedance with circulating current control. The frequency characteristic of impedance for MMC, which is observed from its DC side, is analyzed. Finally, this study investigates the prediction of the DC voltage ripple transfer between two-terminal MMC high-voltage direct current systems under unbalanced conditions. The rationality and accuracy of the impedance model are verified through MATLAB/Simulink simulations and experimental results.
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