http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Victor N. Vasilets,박기동,Valentina A. Surguchenko,Anna S. Ponomareva,Eugene A. Nemetz,Victor I. Sevastianov,배진우 한국고분자학회 2015 Macromolecular Research Vol.23 No.2
Adhesion and proliferation of NIH/3Т3 mouse fibroblasts on the surfaces of bacterial copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and its mixture with poly(ethylene glycol) with differing crystallinity, surfaceenergy, and mean roughness was investigated. The surface mean roughness of all films on both sides, at the air interfaceand at the glass interface, measured by atomic force microscopy, was higher (from 17.0±1.4 nm to 290.8±7.0 nm)than that of the tissue culture polystyrene control (9.5±0.6 nm). The structure, surface energy, and chemical compositionof bacterial films were studied by differential scanning calorimetry, contact angle measurements, and Fouriertransform infrared (FTIR) spectroscopy. After 48 h, cell proliferation on all surfaces was significantly less than onthe control substrate; however, after 72 and 96 h, cell proliferation was comparable with control on some surfaceswith sufficient roughness. Addition of poly(ethylene glycol) resulted in an increase of adhesion and the metabolicactivity of the cells, even for relatively smooth surfaces. The complex correlation of cell metabolic activity with surfaceenergy and crystallinity for “rough” (mean roughness >100 nm) and “smooth” (mean roughness < 100 nm) surfacesis discussed.