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Homer Nazeran 셀메드 세포교정의약학회 2015 TANG Vol.5 No.1
In this first double-blind-placebo-controlled investigation of the Aeon Patch, electrocardiographic data were acquired from 50 well-hydrated volunteers [21 females and 29 males, age: 19-79, weight: 117 - 334 lbs, height: 5'–6',3''], under 3 different conditions for a total duration of 15 min (5 min/condition). Condition1: Control (C) - while wearing no Patch, Condition 2: Placebo (P) or Active (A) - after wearing either the Placebo or the Aeon Patch for 20 min, and Condition 3: Active (A) or Placebo (P) - after wearing either the Aeon or the Placebo Patch for 20 min. There was a washout period of 15 min between Conditions 2 and 3. All involved in the investigation were blind to the (A) and (P) Patches as they looked exactly the same and were assigned in a random fashion. The hypothesis to be tested was: Wearing the Aeon Patch for 20 min reduces stress. Data were first quality assured and those subjects who showed a parasympathetic response after wearing the Patch within 20 min were identified as early responders. Thirty subjects (60%) achieved a relaxed state after wearing the Aeon Patch as early as 20 min. Statistical analysis (one-sample inference) was used to compare the spectral features of the responders. The normalized LF/HF decreased significantly (24% ± 9% after 20 min) in condition (A) compared to condition (P) with a p-value < 0.047 (n = 30) in responders. Therefore, the hypothesis that wearing the Aeon Patch for 20 min reduces stress was accepted as true.
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Reza Nazeran,Ali Hemmati,Hasan Haji Kazemi 국제구조공학회 2024 Structural Engineering and Mechanics, An Int'l Jou Vol.89 No.5
Since the cost of reconstruction is very high and the structure may have been damaged by an earthquake, we must retrofit the structure. Therefore, the importance of studying this issue is very high in order to achieve the desired resistance against the regulations. The present study involved the numerical and experimental analysis of nine concrete frames, consisting of three concrete frames, three concrete frames with bracing, and three concrete frames with a TADAS damper. The purpose of this study is to strengthen the damaged concrete frame using braces and TADAS dampers. Observations were made of the frames as they were subjected to controlled displacement. Also, ABAQUS software was used to compare numerical and experimental results. According to the results, the software was sufficiently capable of modeling the studied frames. Additionally, a parametric study was conducted on the thickness and number of bending plates. Thickness increases from 8 mm to 12 mm, 8 mm to 15 mm, and 8 mm to 20 mm, increasing the base shear by about 6.7%, 11.1%, and 25%, respectively. Furthermore, increasing the number of plates from 4 to 5, 4 to 6, and 4 to 7 increased base shears by about 4.5%, 8.4%, and 14%, respectively.
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Emily Haltiwanger,Homer Nazeran,Sherry Blake-Greenberg 셀메드 세포교정의약학회 2012 TANG Vol.2 No.1
Acupuncture works by stimulating peripheral sensory nerves and their endings causing an increase in cutaneous blood flow and microcirculation, as well as release of neurotransmitters, neuropeptides, and hormones. SP6 Patch is a nanoscale nontransdermal device that mildly stimulates Stomach 36 (zusanli) and other acupuncture points. As stimulation of these points has been indicated to have an effect on hypothalamic function, it is of great research interest to investigate the effect of SP6 Patch on the physiology of organs that are affected by hypothalamic regulation. Bioelectrical tissue impedance data indicative of cellular physiologic organ function, using an Electro Interstitial Scan (EIS) system, were acquired from hypothalamus, pancreas, liver, intestines, kidneys, thyroid and adrenal glands in 10 (1 male, 9 females) volunteers while wearing the SP6 Patch daily for 1 week. EIS testing was performed at baseline with no patch, 30 min after wearing the patch, and after wearing the patch 12 h/day for 1 week. Subjects were instructed to keep well hydrated during the study period. All subjects served as their own control. The hypothesis was: The SP6 Patch worn 12 h/day on the Stomach 36 acupuncture point for 1 week, may significantly improve cellular physiologic functional status of different organs measured by EIS. All tested organs achieved significant improvement in their functional physiologic status after wearing the SP6 Pach 12 h/day for 1 week compared to baseline with an overall average statistical power > 89%. Based upon these results the hypothesis was accepted as true.
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Effect of IceWave® organic nanoscale patches on reduction of musculoskeletal pain
Emily Piven,Rupesh Dharia,Karen Jones,Chuck Davis,Homer Nazeran 셀메드 세포교정의약학회 2013 TANG Vol.3 No.1
In this pilot dual-site study with LifeWave IceWave® patches, using subjects as their own controls, data were acquired from a convenience sample of 16 males and 24 females, 50% Caucasian-Americans, 50% Hispanic-Americans, ages 20 - 85 with neuromuscular pain. The hypothesis was: the application of IceWave® patches to the skin will reduce one’s perception of pain. Subjects were tested at baseline (without any patches), and then at 1 and 3 h on day 1 and at 1 h on days 2 - 5 after patch application. At every time point, the mean change, indicative of one’s perception of pain, was highly significantly (p < 0.0001) reduced, with a statistical power of 100% compared to baseline. Based on these findings, the hypothesis was accepted as true.
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