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        Catheter Ablation of Ventricular Tachycardia in Patients with Post-Infarction Cardiomyopathy

        Babak Nazer,Edward P Gerstenfeld 대한심장학회 2014 Korean Circulation Journal Vol.44 No.4

        Monomorphic ventricular tachycardia (VT) in patients with post-infarction cardiomyopathy (CMP) is caused by reentry through slowly con-ducting tissue with in areas of myocardial scar. The use of implantable cardioverter-defibrillators (ICDs) has helped to decrease the risk ofarrhythmic death in patients with post-infarction CMP, but the symptomatic and psychological burden of ICD shocks remains significant. Experience with catheter ablation has progressed substantially in the past 20 years, and is now routinely used to treat patients with post-infarction CMP who experience VT or receive ICD therapy. Depending on the hemodynamic tolerance of VT, a variety of mapping techniquesmay be used to identify sites for catheter ablation, including activation and entrainment mapping for mappable VTs, or substrate map-ping for unmappable VTs. In this review, we discuss the pathophysiology of VT in post-infarction CMP patients, and the contemporarypractice of catheter ablation.

      • A Joint Typicality Approach to Compute–Forward

        Lim, Sung Hoon,Feng, Chen,Pastore, Adriano,Nazer, Bobak,Gastpar, Michael IEEE 2018 IEEE transactions on information theory Vol.64 No.12

        <P>This paper presents a joint typicality framework for encoding and decoding nested linear codes in multi-user networks. This framework provides a new perspective on compute–forward within the context of discrete memoryless networks. In particular, it establishes an achievable rate region for computing a linear combination over a discrete memoryless multiple-access channel (MAC). When specialized to the Gaussian MAC, this rate region recovers and improves upon the lattice-based compute–forward rate region of Nazer and Gastpar, thus providing a unified approach for discrete memoryless and Gaussian networks. Furthermore, our framework provides some valuable insights on establishing the optimal decoding rate region for compute–forward by considering joint decoders, progressing beyond most previous works that consider successive cancellation decoding. Specifically, this paper establishes an achievable rate region for simultaneously decoding two linear combinations of nested linear codewords from <TEX>$K$</TEX> senders.</P>

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        Potentiometric Back Titration of Isoniazid in Pharmaceutical Dosage Forms Using Copper Based Mercury Film Electrode

        Gajendiran, M.,Nazer, M.M. Abdul Kamal Korean Chemical Society 2011 대한화학회지 Vol.55 No.4

        구리수은막 전극(CBMFE)으로 전위차 역적정함으로써 이소니아자이드(INH)를 정량하는 간단하고 빠른 방법이다. 순수한 형태와 투약형태에 대해서 1.0-10.0 mg 범위에서 정량 할 수 있도록 적정조건을 설정하였다. 방법의 정밀도와 정확도는 통계적인 방법으로 평가되었으며, 정제와 시럽속에 함유된 INH 정량법은 F-시험과 t-시험을 통하여 영국약전(BP) 방법과 비교하였다. A simple, rapid potentiometric back titration of Isoniazid (INH) in the presence of Rifampicin (RIF) in tablets and syrups is described. The method is based on the oxidation of INH by a known excess of copper (II) ion and the back titration of unreacted copper (II) ion potentiometrically with ascorbic acid using a lab-made Copper Based Mercury Film Electrode (CBMFE). The titration conditions have been optimized for the determination of 1.0-10.0 mg of INH in pure and dosage forms. The precision and accuracy of the method have been assessed by the application of lack-of-fit test and other statistical methods. Interference was not caused by RIF and other excipients present in dosage forms. Application of the method for INH assay in tablets and syrups was validated by comparison of the results of proposed method with that of the British Pharmacopoeia (BP) method using F- and t- statistical tests of significance.

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